CAS: 18088-01-2; (2,6-Dimethylpyridin-4-yl)Methanol

相似化合物

54221-93-1 18206-06-9 142896-15-9

上下游产品

CAS号1073-23-0 2,6-二甲基吡啶 N-氧化物 | CAS号108-48-5 2,6-二甲基吡啶 | CAS号18206-06-9 2,6-二甲基吡啶-4-甲醛 | CAS号120739-87-9 2,6-二甲基-4-氯甲基吡啶 | CAS号79313-02-3 4-(溴甲基)-2,6-二甲基吡啶

📜2,6-二甲基吡啶 N-氧化物置于dipotassium Peroxodisulfate体系中,用 二氯甲烷,水 用作溶剂,化学反应 6.0H,反应生成2,6-二甲基-3-羟甲基吡啶
参考文献:Selective Photosensitization Through An And Logic Response: Optimization Of The Ph And Glutathione Response Of Activatable Photosensitizers
标题:Selective Photosensitization Through An And Logic Response: Optimization Of The Ph And Glutathione Response Of Activatable Photosensitizers
摘要:一个分子and逻辑门,即一种可激活的光敏剂,需要超过阈值的酸性(ph)和gsh才能发挥全部活性.
Doi:10.1039/c5Cc01261A

专利信息

专利号:US-5736535-A
优先权日:1992-04-16
标 题:1-pyrimidinylacetamide compounds which are inhibitors of human leukocyte elastase
发明人：BERNSTEIN PETER ROBERT; EDWARDS PHILIP DUKE; SHAW ANDREW; SHENVI ASHOKKUMAR BHIKKAPPA; THOMAS ROYSTON MARTIN; VEALE CHRIS ALLAN; WARNER PETER; WOLANIN DONALD JOHN
权利人:ZENECA LTD
摘要:The present invention relates to certain novel substituted derivatives which are 1-pyrimidinylacetamide derivatives of formula I, ##STR1## which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these substituted derivatives, processes for preparing the substituted derivatives, pharmaceutical compositions containing such substituted derivatives and methods for their use.

专利号:US-5254558-A
优先权日:1991-08-15
标 题:Substituted 1,3-diazines as leukocyte elastase inhibitors
发明人：BERNSTEIN PETER R; EDWARDS PHILIP D; THOMAS ROYSTON M; VEALE CHRIS A; WARNER PETER; WOLANIN DONALD J
权利人:ICI PLC
摘要:The present invention relates to certain novel substituted heterocycles which are 1-pyrimidinylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these substituted heterocycles, processes for preparing the substituted heterocycles, pharmaceutical compositions containing such substituted heterocycles and methods for their use.

专利号:US-5521179-A
优先权日:1991-04-18
标题 :Heterocyclic amides
发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.