CAS: 61-33-6; Benzylpenicillin

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CAS号551-16-6 6-氨基青霉烷酸 | CAS号5187-94-0 ampicillin Trih... | CAS号103-80-0 苯乙酰氯 | CAS号1254-56-4 benzyl 6β-pheny... | CAS号3956-31-8 benzyl (2S,5R,6... | CAS号36273-76-4 6β-(4-nitro-ben... | CAS号41731-15-1 3-cyclohexyloxy... | CAS号69-53-4 氨苄西林 | CAS号110775-95-6 Sodium 2-(2-ami... | CAS号551-16-6 6-氨基青霉烷酸 | CAS号103-82-2 苯乙酸 | CAS号52-67-5 D-青霉胺 | CAS号13057-98-2 2-Thiazolidinea... | CAS号3264-88-8 benzylpenicille... | CAS号13093-87-3 青霉素EP杂质D | CAS号113-98-4 青霉素钾 | CAS号103-81-1 2-苯乙酰胺

Penicillin G Potassium 反应生成 青霉素
参考文献:Beregszaszi,Eva;Polya,Kalman;Vig,Janos;Seres,Peter;Fabian,Ferenc;Faz+
标题:Beregszaszi,Eva;Polya,Kalman;Vig,Janos;Seres,Peter;Fabian,Ferenc;Faz+

专利信息

专利号:US-11840544-B2
优先权日:2018-07-02
标 题 :Intermediates in the synthesis of C3-substituted cephalosporins
发明人：MADELA KAROLINA
权利人:NORBROOK LAB LTD
摘要:Disclosed herein are novel and inventive methods for preparing intermediates in the synthesis of C3-substituted cephalosporins. One preferred C3-substituted cephalosporin of clinical interest is Cefovecin. Accordingly, the present invention provides for methods of preparing reactive halogen intermediates for use in the synthesis of C3-substituted cephalosporins, such as Cefovecin. In the case of Cefovecin the reactive intermediates are of the formula:

专利号:EP-2173892-B8
优先权日:2007-07-27
标题:Process for the preparation of immobilised recombinant Penicillin Acylase biocatalyst from Achromobacter sp CCM 4824 expressed in E. coli BL21 CCM 7394 and its use for the synthesis of beta-lactam antiobiotics
发明人：DATLA ANUPAMA; RAJASEKAR VYASARAYANI WILLIAMS; KYSLIK PAVEL; BECKA STANISLAV; KRISHNAKANT ASHAR TRUPTI; YOGESH ZAMBRE SUJATA; NIKUNJ KUMAR
权利人:FERMENTA BIOTECH LTD
摘要:The present invention discloses isolation of Penicillin Acylase (PA) from Achromobacter sp CCM 4824 expressed in recombinant strain E. coli BL21 CCM 7394 bearing the recombinant plasmid pKXIP1 and processing of PA into biocatalyst useful for the industrial synthesis of antibiotics. More particularly the invention discloses a synthesis of semi-synthetic β-lactam antibiotics in the reaction mixture consisting of activated acyl-donor (D-p-hydroxyphenylglycine methyl ester or amide for Amoxicillin and Cefadroxil; D-phenylglycine methyl ester or amide for Ampicillin and Cephalexin) and nucleophile (6-APA or 7-ADCA) catalyzed by PA obtained from recombinant E. coli BL21 CCM 7394 as the biocatalyst.

专利号:US-2024197774-A1
优先权日:2021-04-16
标 题:Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
发明人：LOPEZ-RIBOT JOSE; VAZQUEZ-MUNOZ ROBERTO
权利人:UNIV TEXAS
摘要:Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

专利号:US-5847116-A
优先权日:1994-12-09
标 题 :Process for the preparation of intermediates useful in the synthesis of cephalosporins
发明人：WALKER DEREK; LEE JUNNING; MARTIN CHARLES R; ZHANG HAIYAN; SOGLI LORIS; BERNASCONI ERMANNO; MENON VINOD PARAKKAL
权利人:SCHERING CORP; ANTIBIOTICOS SA
摘要:A process is described for preparing 3-exomethylene cephalosporanic acid derivatives for use in the synthesis of cephalosporin antibiotics such as ceftibuten. The process comprises electrochemical reduction of a compound of the formula (IV) ##STR1## wherein: R 3 is ##STR2## is an optional sulfoxide group; n is 2 or 3; R 1 is H and R is H or NHR 2 , where R 2 is H or a protecting group selected from C 6 H 5 CH 2 OC(O)--, C 6 H 5 C(O)-- or C 1 -C 6 alkoxy-C(O)--; or wherein R and R 1 together with the carbon atom to which they are attached comprise --C(O)--, and produces the desired 3-exomethylene compounds with low levels of the corresponding 3-methyl tautomers.

专利号:US-9085550-B2
优先权日:2005-01-21
标题 :Ligands for estrogen related receptors and methods for synthesis of said ligands
发明人：FORMAN BARRY; YU DONNA
权利人:FORMAN BARRY; YU DONNA; HOPE CITY
摘要:Estrogen-Related Receptor (ERR) modulating compounds and methods for synthesis of said compounds are described.

专利号:US-8071330-B2
优先权日:2004-12-27
标题:Process for the synthesis of cefaclor
发明人：MOODY HAROLD MONRO; DOOREN THEODORUS JOHANNES GODFRIED MARIA VAN
权利人:MOODY HAROLD MONRO; DOOREN THEODORUS JOHANNES GODFRIED MARIA VAN; DSM IP ASSETS BV
摘要:The present invention relates to a process for the synthesis of cefaclor, which process comprises reacting 7-amino-3-chloro cephalosporanic acid (7-ACCA) with D-phenylglycine in activated form (PGa) in the presence of an enzyme in a reaction mixture to form cefaclor, wherein at least part of 7-ACCA and/or PGa are added to the reaction mixture during the course of the reaction. The invention also relates to an aqueous mixture comprising an amount of cefaclor of >10 (w/w) %, an amount of 7-amino-3-chloro cephalosporanic acid of <2 (w/w) %, and an amount of D-phenyl glycine of <2 (w/w) % and a process for the recovery of cefaclor from this aqueous mixture. The invention also relates to cefaclor in crystal form having an absorbance at 400 nm (A 400 ) of less than 0.250.