CAS: 55804-67-6; 10-Acetyl-2,3,6,7-Tetrahydro-1H,5H,11H-Pyrano[2,3-F]Pyrido[3,2,1-Ij]Quinolin-11-One

上下游产品

CAS号63149-33-7 8-羟基久洛尼定-9-甲醛 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号536-90-3 间氨基苯甲醚 | CAS号63468-83-7 8-甲氧基久洛利定 | CAS号41175-50-2 8-羟基久洛里定

3-氨基苯酚置于哌啶,碳酸氢钠,三氯氧磷体系中,用 乙醇,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 19.5H,反应生成 香豆素 334
参考文献:近红外荧光染料的合成及其在活细胞中 Hso3− 快速检测中的应用
标题:近红外荧光染料的合成及其在活细胞中 Hso3− 快速检测中的应用
摘要:So 2及其衍生物(hso 3-,So 3 2-)在许多工业和生物体中发挥着重要的作用.基于香豆素和苯并吡喃糖,一种有前途的 Nir 比率荧光探针 Baoa (11-Oxo-2,2',3,3',6,7,7',8'-octahydro-1H,1'H,5H,6' H,11H-[10,12'-Bipyrano [2,3-F] Pyrido [3,2,1-Ij] Quinolin]-13'-Ium Perchlorate) 被设计和开发用于快速,灵敏地检测 Hso 3-.传感机制是迈克尔加成反应,其中强亲核的hso 3-攻击碳-碳双键并形成baoa-Hso 3.荧光比 I 490之间的优异线性校准曲线/i 722和 Hso 3-的浓度范围为 1.25-8.75 μmol/l,Lod 计算为 63.0 Nmol/l.细胞实验表明,Baoa不仅可以定位线粒体,溶酶体,内质网和高尔基体,还可以检测活细胞中的外源性hso
DOI:10.1016/j.Dyepig.2021.109753

专利信息

专利号:US-12006540-B2
优先权日:2015-09-28
标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
发明人：JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J
权利人:UNIV COLUMBIA
摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

专利号:US-11959137-B2
优先权日:2015-09-28
标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis

专利号:US-2024376536-A1
优先权日:2015-09-28
标题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

专利号:US-2022411860-A1
优先权日:2015-09-28
标题:Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

专利号:US-2023160000-A1
优先权日:2015-09-28
标 题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

专利号:US-2023028388-A1
优先权日:2015-09-28
标 题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis