CAS: 555-03-3; 3-Nitroanisole

该化合物是有机化合物,其特征是附于苯环的硝基化合物(-NO2)和甲氧化合物(-OCH3),在室温时为黄色的灰色固体,以其芳香特性而著称;硝基苯组位于与影响其反应和物理特性的甲氧基组相对的元体位置;3-硝基苯在乙醇和乙醇等有机溶剂中可溶解,但水溶性有限;主要用于合成各种化学化合物,并在生产药品和农用化学品时用作中间体;化合物具有中度毒性,在处理时应采取适当安全措施;此外,它可发生各种化学反应,包括硝化和减少,使其在有机合成中成为多用途建筑块.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

3-fluoro-1-nitrobenzene sodium methylate meta-nitrophenol methyl p-toluene sulfonate 2-chloromethyl-5-nitro-anisole 1-iodo-4-methoxy-2-nitrobenzene 2,3-dinitroanisole 6-methoxy-2-nitrophenol

合成工艺路线路线简述

    📜Syn-2-Nitro-4-Methoxyphenylazoethylether置于乙醇,Sodium Ethanolate体系中,化学反应生成 3-硝基苯甲醚
    参考文献:Reactions Of Aryl Diazonium Salts And Arylazo Alkyl Ethers. 7. Kinetic Studies Of The Decomposition Of Z Ethers Derived From Some Substituted 2-Nitrobenzenediazonium Salts
    标题:Reactions Of Aryl Diazonium Salts And Arylazo Alkyl Ethers. 7. Kinetic Studies Of The Decomposition Of Z Ethers Derived From Some Substituted 2-Nitrobenzenediazonium Salts
    摘要:
    DOI:10.1021/jo00140A017

    海关参考信息

    专利信息


    专利号:US-5512701-A
    优先权日:1995-06-07
    标题:Process for the synthesis of vinyl sulfenic acid derivatives
    发明人：HOARD DAVID W; LUKE WAYNE D
    权利人:LILLY CO ELI
    摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.

    专利号:WO-2016122325-A1
    优先权日:2015-01-30
    标 题:Methods for providing intermediates in the synthesis of atorvastatin.
    发明人：DÖMLING ALEXANDER STEPHAN SIEGFRIED
    权利人:UNIV GRONINGEN
    摘要:The invention relates to the field of medicinal chemistry, In particular, it relates to methods for providing intermediates in the synthesis of Atorvastatin, a competitive inhibitor of HMG-Co A reductase. Provided is a process for providing a compound having a Formula (I) or a pharmaceutically acceptable salt, ester, amide or stereoisomer thereof, comprising reacting in a 4 component Ugi-reaction in a single reaction mixture the compounds of formula A, formula B, formula C and formula D.

    专利号:US-6372945-B1
    优先权日:1995-06-07
    标 题 :Process for the synthesis of vinyl sulfoxides
    发明人：AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
    权利人:LILLY CO ELI
    摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides

    专利号:US-5606076-A
    优先权日:1995-06-07
    标 题 :Process for the synthesis of benzo[b]thiophenes
    发明人：AIKINS JAMES A; ZHANG TONY Y
    权利人:LILLY CO ELI
    摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.

    专利号:US-5569772-A
    优先权日:1995-06-07
    标 题:Process for the synthesis of benzo[b]thiophenes
    发明人：HOARD DAVID W; LUKE WAYNE D
    权利人:LILLY CO ELI
    摘要:The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.

    专利号:US-5606075-A
    优先权日:1995-06-07
    标 题:Process for the synthesis of benzo[b]thiophenes
    发明人：HOARD DAVID W; LUKE WAYNE D
    权利人:LILLY CO ELI
    摘要:The present invention is directed to new processes for the synthesis of 2-aryl benzo[b]thiophenes.

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    合成参考文献


    摘要:Claver, C.; Peñafiel, I.; Urrutigoïty, M.; Kalck, P., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 313.
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