CAS: 540-23-8; P-Toluidine Hydrochloride

该化合物是一种有机化合物,其特征是附于甲基代苯环的有矿功能组,它看起来像白色的离白晶晶状固体,在水中可溶解,反映其盐化形式.该化合物的分子配方包括碳和氮,表明其芳香的含汞结构.p-Tluidine主要用于染料,色素和药品的合成,它是各种化学反应的中间体.必须指出,p-tluidine可能是危险的;它被归类为潜在的致癌物,在接触时可能构成健康风险,在处理过程中需要采取适当的安全措施.该化合物的熔点和沸点可能不同,但由于其在室内温度的固体状态,它通常表现出相对较低的挥发性.

⚠️危险化学品目录(2015年版)急性毒性-经口,类别3* 《化妆品禁用原料目录》
英文名称P-Toluidine Hydrochloride
中文名称4-甲基苯胺盐酸盐
IUPAC名称4-methylaniline;hydrochloride
其它别名p-Toluidine hydr°Chloride
CAS编号540-23-8
MFCD编号:MFCD00035497
EINECS号:208-740-8
FDA UNII编号:PT5II901IF
分子式:C7H10ClN分子量:143.61
产品CID: 2500810
产品分类有机原料 → 氨基化合物 → 无环单胺、多胺及其衍生物和盐

相似结构搜索
产品信息参考;
InChIKey: JQKBUTDZZRGQDR-UHFFFAOYSA-N
InChI=1S/C7H9N.ClH/c1-6-2-4-7(8)5-3-6;/h2-5H,8H2,1H3;1H
计算化学: 氢键受体数1.0氢键供体数2.0可旋转键数0.0

MSDS等安全信息

GHS象形图
GHS符号GHS08 & GHS06 & GHS09;
注释: Health hazard & Skull and crossbones & Environment
危险类别致癌性类别2
急性毒性类别3(吸入)
急性毒性类别3(经皮)
急性毒性类别3(经口)
严重眼刺激类别2
皮肤致敏类别1
水生急性毒性类别1
急性毒性类别4(经口)
严重眼刺激类别2A
水生慢性毒性类别1
警示词Danger(危险)
危险描述H351 |怀疑致癌.
H331 |吸入会中毒.
H311 |皮肤接触会中毒.
H301 |吞咽会中毒.
H319 |造成严重眼刺激.
H317 |可能引起皮肤过敏反应.
H400 |对水生生物毒性极大.
H302 |吞咽有害.
H410 |对水生生物毒性极大并具有长期持续影响.
防范说明P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338
危险等级6.1(a)
UN编号UN 2811 6.1/PG 1
危险品标志T,N
包装等级II
安全声明28-36/37-45-61
危险类别码23/24/25-36-40-43-50
WGK Germany3

欧盟法规

统一分类与标签压力设备指令-第1组危险流体ECHA物质ECHA物质食品接触材料-禁用CMR物质化妆品禁用物质清单C&L通报工作场所安全标识要求REACH预注册废弃物危险特性清单

上下游产品

合成工艺路线路线简述

📜4-硝基甲苯置于二乙基硅烷,四(3,5-二(三氟甲基)苯基)硼酸钠,Co(Dppbsa),盐酸体系中,用甲苯,乙醚作为反应溶剂,以88 %的收率获得产物4-甲基苯胺盐酸盐
参考文献:Co(Dppbsa)-Catalyzed Reductive N,N-Dimethylation Of Nitroaromatics With Co2 And Hydrosilane
标题:Co(Dppbsa)-Catalyzed Reductive N,N-Dimethylation Of Nitroaromatics With Co2 And Hydrosilane
摘要:合成了一种新型半夹心 Co(dppbsa)([co]),并用于催化硝基芳烃与二氧化碳和氢硅烷的 N,N-二甲基化反应.该催化剂还能高效地将硝基芳烃还原成芳香胺.
DOI:10.1039/d3Gc02517A

海关参考信息

2902300000-甲苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6846922-B1
优先权日:1998-06-02
标题 :Activators for oligonucleotide synthesis
发明人：MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T
权利人:ISIS PHARMACEUTICALS INC
摘要:The present invention relates to improved methods for the preparation of nucleoside phosphoramidites and oligonucleotides. In one aspect, the methods of the invention are used to prepare phosphitylating reagents using pyridinium salts as activators. In a further aspect, the methods of the invention are used to prepare internucleoside linkages using activators which include at least one pyridinium salt and at least one substituted imidazole. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having 2â€²-substituents using imidazolium or benzimidazolium salts as an activator. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having bioreversible protecting group that confers enhanced chemical and biophysical properties, without exocyclic amine protection, using imidazolium or benzimidazolium salts as an activator.

专利号:US-11628423-B2
优先权日:2018-05-30
标题:Morphologically controlled synthesis of ferric oxide nano/micro particles

专利号:EP-1084134-A4
优先权日:1998-06-02
标题 :ACTIVATORS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES

专利号:CN-114874139-B
优先权日:2022-05-27
标题:Synthesis method of 1-benzyl or allyl 3, 4-dihydroisoquinoline