CAS: 5108-94-1; Mytatrienediol
该化合物是属于多元醇类别的化学化合物,其特点是存在多种氢氧基(-OH)组,该化合物通常具有无色至浅黄色液体等性质,其粘度相对较低;Mytatrienediol在水和各种有机溶剂中可溶解,使其具有多种用途;其结构包括三元配置,有助于其在有机合成中产生反应和潜在用途;氢氧基组的存在允许氢结合,影响其物理特性和与其他物质的相互作用;Mytatrienediol可用于生产聚合物,表面活性剂或化学合成中的中间体;然而,与任何化学物质一样,应当遵循具体的安全和处理准则,以减少其使用可能带来的危害;始终参考材料安全数据表,以了解关于处理和安全防范措施的详细资料.
- 英文名称Mytatrienediol
- 中文名称(16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇
- IUPAC名称(8R,9S,13S,14S,16S,17R)-3-methoxy-13,16-dimethyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol
- 其它别名(16S,17R)-3-Methoxy-13,16-Dimethyl-7,8,9,11,12,14,15,17-Octahydro-6H-Cyclopenta[a]Phenanthrene-16,17-Diol; 3-Methoxy-16-Methylestra-1,3,5(10)-Triene-16β,17β-Diol; 3-Methoxy-16α-Methylestra-1,3,5(10)-Triene-16β,17β-Diol; Manvene; Mytatrienediol; Estra-1,3,5(10)-Triene-16,17-Diol, 3-Methoxy-16-Methyl-, (16β,17β)-; Anvene
- CAS编号5108-94-1
- FDA UNII编号:1G3TKH1O14
- 分子式:C20H28O3分子量:316.44
- 产品CID: 1499740
- 产品分类有机原料 → 脂质和类脂质分子 → 类固醇和类固醇衍生物
物理性质
MSDS等安全信息
上下游产品
17Beta-羟基-3-甲氧基-1,3,5(10)-雌甾三烯-16-酮 3-Methoxy-17β-Hydroxy-Estra-1,3,5(10)-Trien-16-One 24721-15-1合成工艺路线路线简述
📜3-Methoxy-16-Methylene-Estra-1,3,5(10)-Trien-17-One置于sodium Hydroxide,Lithium Aluminium Tetrahydride,双氧水体系中,用 四氢呋喃,叔丁醇 作为反应溶剂,化学反应 4.0H,反应生成 (16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇
参考文献:Stereoselectivity In The Epoxidation And Cis-Hydroxylation Of 16-Methylene-Estra-1,3,5(10)-Trienes
标题:Stereoselectivity In The Epoxidation And Cis-Hydroxylation Of 16-Methylene-Estra-1,3,5(10)-Trienes
摘要:Epoxidation Of 3-Methoxy-16-Methylene-Estra-1,3,5(10)-Trien-17-One In The Presence Of Alkaline Hydrogen Peroxide Gives Rise To (16R)-And (16S)-Spiro[3-Methoxy-17-Oxoestra-1,3,5(10)-Triene-16,2'-Oxirane] In Similar Proportions. Epoxidation Of The Corresponding 16-Methlene 17 Beta-Alcohol And 16-Methylene-17 Beta-Acetate With M-Chloroperbenzoic Acid Does Not Display Any Significant Directing Effects Associated With Allylic Functionality,Whereas Sharpless Epoxidation Of The 16-Methylene 17 Beta-Alcohol Is Highly Stereoselective,Leading Exclusively To The (16R) Isomer. Cis-Hydroxylation Of The 16-Methylene 17-Ketone With Osmium Tetroxide/4-Methylmorpholine-4-Oxide Proceeds Stereoselectively To Give Mainly 16 Alpha-Hydroxy-16 Beta-Hydroxymethyl-3-Methoxyestra-1,3,5(10)-Trien-17-One. The Isomeric Addition Products Derived From These Reactions Are Correlated By Appropriate Interconversions,And The Assignments Are Corroborated By Comparative Reactivity Of Derived Products.
DOI:10.1016/0039-128X(94)90018-3
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: COOK DL, CALHOUN DW, EDGREN RA. Lipodiatic and antiatherogenic properties of mytatrienediol and various estrogenic substances. Arch Int Pharmacodyn Ther. 1962 Jan 1;135:91-104.
合成参考文献
参考文献:10.1016/j.jmgm.2006.01.007
摘要:Li H, Ung CY, Yap CW, Xue Y, Li ZR, Chen YZ. Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of Molecular Graphics and Modelling. 2006 Nov;25(3):313–23. doi: 10.1016/j.jmgm.2006.01.007.
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