CAS: 50443-60-2; Revefenacin Impurity 9

相似化合物

14925-09-8 6301-18-4 1087788-51-9

📜5-((1R)-2-Amino-1-{[Tert-Butyl(Dimethyl)Silyl]Oxy}Ethyl)-8-Hydroxyquinolin-2(1H)-One Acetate,三乙酰氧基硼氢化钠,二氯甲烷 在 水体系中,用 甲醇作为反应溶剂,反应 16.5H,获得 Biphenyl-2-Ylcarbamic Acid
参考文献:Biphenyl Derivatives
标题:Biphenyl Derivatives
摘要:本发明提供了式i的双苯基衍生物:其中r1,R2,R3,R4,R5,R6,R7,W,A,B和c如规范中所定义,或其药学上可接受的盐,溶剂或立体异构体.本发明的双苯基衍生物具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性,因此,这种双苯基衍生物可用于治疗肺部疾病,如慢性阻塞性肺疾病和哮喘.

专利信息

专利号:US-9035061-B2
优先权日:2010-07-13
标题:Process for preparing a biphenyl-2-ylcarbamic acid
发明人：COLSON PIERRE-JEAN
权利人:COLSON PIERRE-JEAN; THERAVANCE BIOPHARMA R & D IP LLC
摘要:The invention provides a process of preparing an intermediate useful in the synthesis of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and a process of preparing a crystalline freebase of the ester.

专利号:EP-1930323-A1
优先权日:2004-03-11
标 题:Biphenyl compounds useful in the synthesis of muscarinic receptor antagonists

专利号:ES-2345640-T3
优先权日:2004-03-11
标 题 :USEFUL BIFENYL COMPOUNDS IN THE SYNTHESIS OF ANTAGONISTS OF THE MUSCARINIC RECEPTOR

专利号:EP-1930323-B1
优先权日:2004-03-11
标 题:Biphenyl compounds useful in the synthesis of muscarinic receptor antagonists

专利号:WO-0056709-A1
优先权日:1999-03-24
标 题:Indolinone compounds as kinase inhibitors
发明人：TANG PENG CHO; SUN LI; MCMAHON GERALD; MILLER TODD ANTHONY; SHIRAZIAN SHAHRZAD; WEI CHUNG CHEN; HARRIS G DAVIS; XIAOYUAN LI; LIANG CONGXIN
权利人:SUGEN INC; TANG PENG CHO; SUN LI; MCMAHON GERALD; MILLER TODD ANTHONY; SHIRAZIAN SHAHRZAD; WEI CHUNG CHEN; HARRIS G DAVIS; XIAOYUAN LI; LIANG CONGXIN
摘要:The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

专利号:US-6689806-B1
优先权日:1999-03-24
标 题 :Indolinone compounds as kinase inhibitors
发明人：TANG PENG CHO; SUN LI; MCMAHON GERALD; MILLER TODD ANTHONY; SHIRAZIAN SHAHRZAD; WEI CHUNG CHEN; HARRIS JR G DAVIS; LI XIAOYUAN; LIANG CONGXIN
权利人:SUGEN INC
摘要:The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.