CAS: 4682-48-8; Lactosylceramide

该化合物是一种在细胞识别和信号过程方面起着重要作用的甘蓝素激素,由与乳糖糖糖细胞相连的彩虹脊柱组成,它有助于其细胞病原性质,使它能融入生物膜.该化合物主要存在于各种细胞类型的膜中,特别是大脑和其他...

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合成工艺路线路线简述

    📜,Cytidine-5'-Monophosphono-N-Acetylneuraminic Acid,5'-胞苷酸,Bodipy Lactosylceramide,在 Chloroform Methanol,氮体系中,用 Chloroform Methanol 作为反应溶剂,化学反应 1.67H,反应生成 乳酰基-N-脂酰基鞘氨醇(牛)
    参考文献:Drug For Preventing And Treating Atherosclerosis
    标题:Drug For Preventing And Treating Atherosclerosis
    摘要:本发明涉及一种预防/治疗动脉粥样硬化的药物,包括gm3合成酶抑制剂或抑制gm3合成酶基因表达的抑制剂,一种诊断动脉粥样硬化的诊断产品,包括针对gm3合成酶的抗体,使用gm3或gm3合成酶作为动脉粥样硬化的诊断标志物的用途等.同时还包括使用gm3合成酶抗体进行动脉粥样硬化的诊断方法等.

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    专利号:US-2024360247-A1
    优先权日:2021-08-10
    标 题:Compositions and methods for treatment of cancer
    发明人:CHATTERJEE SUBROTO
    权利人:UNIV JOHNS HOPKINS
    摘要:Compositions in the prevention and treatment of cancers, such as colorectal cancer or diseases associated with abnormal levels of β-1,4-galactosyltransferase-V (β-1,4-GalT-V), include at least one inhibitor of glycosphingolipid synthesis.

    专利号:WO-2009040816-A1
    优先权日:2007-09-26
    标题:Methods of treating lysosomal storage disorders
    发明人:HOROWITZ MIA; RON RONEN IDIT
    权利人:UNIV RAMOT; HOROWITZ MIA; RON RONEN IDIT
    摘要:The sphingolipid storage disease (SLSD) is selected from the group consisting of Gaucher' s Disease, Niemann-Pick Disease, Krabbe' s Disease (Globoid leukodystrophy), Metachromatic leukodystrophy, Ceramide lactoside lipidosis, Fabrys Disease, Tay-Sachs Disease, Sandhoffs Disease and Landing's Disease. The cholesterol synthesis inhibitor is selected from the group consisting of mevastatin, lovastatin, pravastatin, fluvastatin, simvastatin, rosuvastatin, cerivastatin and atorvastatin.

    专利号:EP-0698012-B1
    优先权日:1993-05-13
    标题:Use of deoxygalactonojirimycin derivatives for inhibiting glycolipid synthesis

    专利号:US-5656641-A
    优先权日:1993-05-13
    标题 :Method of inhibiting glycolipid synthesis

    专利号:US-6291657-B1
    优先权日:1993-05-13
    标题 :Deoxygalactonojirimycin derivatives
    发明人:PLATT FRANCES M; NEISES GABRIELLE R; DWEK RAYMOND A; BUTTERS TERRY D
    权利人:MONSANTO CO
    摘要:Novel N-alkyl derivatives of deoxygalactonojirimycin are provided in which said alkyl contains from 3-6 carbon atoms. These novel compounds are useful for selectively inhibiting glycolipid synthesis.

    专利号:US-5472969-A
    优先权日:1993-05-13
    标 题:Method of inhibiting glycolipid synthesis

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