CAS: 41411-64-7; 2,3,3',4,4',5,6-Heptachloro-1,1'-Biphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由多氯分体组成的双联苯分子组成;该化合物的特点是与双联苯结构相连的七氯原子,有助于其稳定性和环境持久性;七氯联苯的特点是其具有疏水性,低挥发性和抗降解性,这可能导致生物生物体的生物累积;它通常存在于工业应用中,尽管由于毒性影响,包括潜在的致癌性和内分泌干扰,它的使用在许多国家受到限制或禁止;该化合物经常在环境样品中进行分析,以评估污染程度及其对生态系统的影响;由于其结构复杂,七氯联苯可以表现出各种异构体形式,影响其在生物系统中的化学行为和相互作用;
- 英文名称2,3,3',4,4',5,6-Heptachloro-1,1'-Biphenyl
- 中文名称2,3,3',4,4',5,6-七氯-1,1'-联苯
- IUPAC名称1,2,3,4,5-pentachloro-6-(3,4-dichlorophenyl)benzene
- 其它别名2,3,3',4,4',5,5'-七氯联苯 Pcb-190-C; 2,3,3',4,4',5,6-Heptachlorobiphenyl
- CAS编号41411-64-7
- MFCD编号:MFCD00152526
- FDA UNII编号:M03P5STJ2P
- 分子式:C12H3Cl7分子量:395.32
- 产品CID: 1428568
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H302-H315-H319-H335
- 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
CAS号118-74-1 六氯苯 | CAS号20555-91-3 3,4-二氯碘苯 | CAS号608-93-5 五氯苯 | CAS号95-76-1 3,4-二氯苯胺合成工艺路线路线简述
📜六氯苯,3,4-二氯碘苯置于乙基溴化镁体系中,用 四氢呋喃 作为反应溶剂,化学反应生成 2,3,3',4,4',5,6-七氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:S50 | CCSCOMPEND | The Unified Collision Cross Section (CCS) Compendium | DOI:10.5281/zenodo.2658162
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. http://monographs.iarc.fr/index.php
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