CAS: 28523-86-6; Sevoflurane

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CAS号26103-07-1 2-(氯甲氧基)-1,1,1,... | CAS号373-53-5 氟碘甲烷 | CAS号920-66-1 六氟异丙醇 | CAS号373-52-4 氟溴甲烷 | CAS号593-70-4 氯氟甲烷 | CAS号406-58-6 1,1,1,3,3-五氟丁烷 | CAS号50-00-0 甲醛 | CAS号1152045-94-7 methyl 3,3,3-tr... | CAS号97614-43-2 2-脱氧-2-氟-1,3,5-... | CAS号26103-07-1 2-(氯甲氧基)-1,1,1,... | CAS号13171-18-1 六氟异丙基甲醚 | CAS号58109-34-5 1,1,3,3,3-五氟-2-...

二氯甲基醚置于brf3体系中,化学反应生成七氟烷
参考文献:Method For The Preparation Of Fluoromethyl
标题:Method For The Preparation Of Fluoromethyl
摘要:氟甲基-1,1,1,3,3,3-六氟-2-丙基醚的制备是通过溴三氟和甲基-1,1,1,3,3,3-六氯-2-丙基醚或氯甲基-1,1,1,3,3,3-六氯-2-丙基醚反应得到的.具有公式##str1##(其中x+y=3,A+b=3,Z=h Cl或f)的混合氟氯醚中间体通过与溴三氟反应转化为氟甲基-1,1,1,3,3,3-六氟-2-丙基醚.

专利信息

专利号:US-2012177593-A1
优先权日:2009-07-20
标 题 :Synthesis of dendrimer conjugates
发明人：BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH
权利人:BAKER JR JAMES R; ZHANG YUEHUA; THOMAS THOMMEY P; DESAI ANKUR MAHESH; UNIV MICHIGAN
摘要:The present invention relates to novel methods of synthesis of therapeutic and diagnostic dendrimers. In particular, the present invention is directed to novel dendrimer conjugates, novel methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer, inflammatory disease) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer conjugates of the present invention may further comprise at least two different components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. Furthermore, the novel synthesis methods of certain embodiments of the present invention provide significant advantages with regard to total reaction time and simplicity.

专利号:US-7375254-B2
优先权日:2003-01-14
标题:Process for recovery of 1,1,1,3,3,3-hexafluoroisopropanol from the waste stream of sevoflurane synthesis
发明人：ROZOV LEONID A; LESSOR RALPH A
权利人:BAXTER INT
摘要:Provided is a process of obtaining 1,1,1,3,3,3-hexafluoro-2-propanol (“HFIPâ€?) from a composition comprising an HFIP hydrolyzable precursor. The HFIP hydrolyzable precursor is a compound, other than sevoflurane itself, that has an intact 1,1,1,3,3,3-hexafluoroisopropoxy moiety[(CF 3 ) 2 CHO—], and contains one or more moieties susceptible to acidic hydrolysis, such that HFIP is released upon such treatment. The process is useful, among other things, for recovering HFIP from waste streams associated with the synthesis of the inhalation anesthetic, fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether (“sevofluraneâ€?). The process includes heating the composition with a strong protic acid to a temperature effective to hydrolyze at least some of the HFIP hydrolyzable precursor to HFIP, and then isolating the HFIP from the heated composition.

专利号:US-5705710-A
优先权日:1997-01-15
标 题 :Process for the synthesis of hexafluoroisopropyl ethers
发明人：BAKER MAX T; TINKER JOHN H; RUZICKA JAN A
权利人:UNIV IOWA RES FOUND
摘要:This invention relates to a method of synthesizing 1,1,1,3,3,3-hexafluoroisopropyl ether compounds from the reaction of methoxymalanonitrile with a bromine trifluoride composition.

专利号:US-5789630-A
优先权日:1996-02-27
标题:Process for the synthesis of hexafluoropropanes
发明人：BAKER MAX T; RUZICKA JAN A
权利人:UNIV IOWA RES FOUND
摘要:The invention relates to a method of synthesizing 1,1,1,3,3,3-hexafluoropropanes comprsing the additon of BrF 3 to malononitrile.

专利号:US-2015352230-A1
优先权日:2013-01-11
标 题:Synthesis and isolation of dendrimer based imaging systems
发明人：MULLEN DOUGLAS GURNETT; BAKER JR JAMES R; BANASZAK HOLL MARK M; HUANG BAOHUA; DOUGHERTY CASEY; BALL JACK
权利人:UNIV MICHIGAN
摘要:The present invention relates to novel methods of synthesis and isolation of antibodies conjugated with modular dendrimer nanoparticles. In particular, the present invention is directed to antibodies conjugated with novel modular dendrimer nanoparticles having precise numbers of imaging agents, methods of synthesizing the same, compositions comprising such antibodies conjugated with such modular dendrimer nanoparticles, as well as systems and methods utilizing the conjugates (e.g., in imaging settings) (e.g., in diagnostic and/or therapeutic settings) (e.g., for the delivery of therapeutics, imaging, and/or targeting agents).

专利号:US-7605291-B2
优先权日:2006-04-27
标 题 :Method for the preparation of volatile Anesthetics
发明人：MALDONADO ADALBERTO
权利人:MALDONADO ADALBERTO
摘要:The present invention is concerned with the automated control of the synthesis and purification of components useful in the synthesis and purification of volatile anesthetics. The invention is particularly useful in its application to the purification of acetone used in the purification of isoflurane.