CAS: 16940-81-1; Hexafluorophosphoric Acid

该化合物是一种很强的无机酸,其特点是酸度高,并存在六氟原子,与磷原子相连接,通常是一种无色,熏蒸的液体,具有高度腐蚀性,在接触水分时可释放出有毒烟雾.这种酸以其作为强质捐献者的能力而著称,使它成为各种化学反应中的强力酸.六氟磷酸经常用于氟化合物合成,并用作有机反应中的催化剂.其盐类,即六氟磷酸,通常用于生产离子液体和电池中的电解液,由于具有高度反应性,必须谨慎处理,使用适当的安全措施避免与皮肤接触或吸入蒸气.总的来说,六氟磷酸是工业和研究应用中的重要化合物,特别是在氟化化学领域.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    专利信息


    专利号:US-2023286918-A1
    优先权日:2020-07-02
    标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
    发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
    权利人:AKEBIA THERAPEUTICS INC
    摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

    专利号:US-11629137-B2
    优先权日:2017-04-24
    标 题:Methods of manufacturing of niraparib
    发明人:STEWART ALISTAIR; TOTO ANTHONY JOSEPH; CHEN FRANK XING; WU GEORGE
    权利人:TESARO INC
    摘要:Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.

    专利号:US-6458967-B1
    优先权日:2000-06-26
    标 题:Method for preparation of an intermediate dye product
    发明人:DETTY MICHAEL RAY; VIRKLER PETER ROBERT
    权利人:UNIV NEW YORK STATE RES FOUND
    摘要:The present invention provides a novel method for the synthesis of an intermediate dye product having the following formula: n wherein n L is S, Te, or Se; n R 1 and R 2 are either the same or different aryl or alkyl compounds; n R 3 is hydrogen or a short chain alkyl group; and n Z is an anion. n The process to formulate this intermediate compound entails reacting an R 1 -acetylene compound with an R 2 -acetylene compound (compounds A) into an enol ether compound with the R 1 and/or R 2 constituents (compound D). And from compound D, it forms into an intermediate dye compound having an L-based cyclic ring with the R 1 and/or R 2 constituents (compound F). With compound F the desired dye can be made with a greater overall yield for mass production.

    专利号:WO-2024126092-A1
    优先权日:2022-12-14
    标题:Method for producing 5-hmf by converting a syrup in a non-aqueous solvent with extraction of the syrup water upstream of the synthesis
    发明人:BOURAS MERIEM; DANG THI BICH NGOC; FERNANDEZ ESPADA PASTOR MARIA; LORCET HÉLÈNE; PAGOT ALEXANDRE; BREUIL PIERRE-ALAIN
    权利人:IFP ENERGIES NOW
    摘要:The present invention relates to a method for producing a 5-hydroxymethylfurfural (5-HMF) solution, comprising a step a) of bringing a feedstock comprising a hexose into contact with a synthesis solvent and an acid dehydration catalyst, said step being performed at a temperature of between 30 and 200°C, preferably between 50 and 180°C, more preferably between 70 and 150°C and very preferably between 90 and 130°C, and at a pressure of between 0.001 MPa and 10 MPa, preferably between 0.001 MPa and 5 MPa, more preferably between 0.01 MPa and 1 MPa, obtaining a reaction medium and concomitantly extracting the water from the reaction medium, in order to obtain a synthesis effluent comprising 5-HMF and synthesis solvent.

    专利号:WO-2024126091-A1
    优先权日:2022-12-14
    标 题:Method for producing 5-hmf via conversion of sugar in a non-aqueous solvent with water extraction during synthesis
    发明人:BOURAS MERIEM; DANG THI BICH NGOC; FERNANDEZ ESPADA PASTOR MARIA; LARMIER KIM; LORCET HÉLÈNE; PAGOT ALEXANDRE
    权利人:IFP ENERGIES NOW
    摘要:The present invention relates to a method for producing a solution of 5-hydroxymethylfurfural (5-HMF), the method comprising a step a) of bringing a feedstock comprising a hexose into contact with a synthesis solvent and a dehydration acid catalyst, carried out at a temperature of between 30 and 200°C, preferably between 50 and 180°C, more preferably between 70 and 150°C and very preferably between 90 and 130°C, and at a pressure of between 0.001 MPa and 10 MPa, preferably between 0.001 MPa and 5 MPa, and more preferably between 0.01 MPa and 1 MPa, obtaining a reaction medium and concomitantly extracting the water from the reaction medium, to obtain a synthesis effluent comprising 5-HMF and synthesis solvent.

    专利号:US-11634539-B2
    优先权日:2018-09-24
    标题:Polycarbonate block copolymers and methods thereof
    发明人:ALLEN SCOTT D; DEBNATH DIBYENDU
    权利人:SAUDI ARAMCO TECH CO
    摘要:The present disclosure relates to block copolymers comprising, and methods of making thereof, a polycarbonate chain linked to a hydrophilic polymer. Such block copolymers may have the formula B-A-B, where A is a polycarbonate or polyethercarbonate chain and B is a polyether. Provided methods are useful in reducing the amount of waste generated from the synthesis of polycarbonates and provide improved thermal stability and high primary hydroxyl content. Provided block copolymers also have utility as additives in enhanced oil recovery methods, and foam polymer applications.
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    合成参考文献


    摘要:Lu, J.-M.; Shao, L.-X., Science of Synthesis Knowledge Updates, (2020) 3, 388.
    摘要:Wei, W.; Zhao, X., Science of Synthesis Knowledge Updates, (2020) 3, 437.
    摘要:Kirk-Othmer Encyclopedia of Chemical Technology. 4th ed. Volumes 1: New York, NY. John Wiley and Sons, 1991-Present., p. V11 409
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