CAS: 144120-54-7; Fmoc-Glu-Oall

相似化合物

204251-86-5 133464-46-7 204251-33-2

上下游产品

CAS号104091-09-0 N-[(9H-芴-基甲氧基)羰... | CAS号107-18-6 烯丙醇 | CAS号71989-18-9 Fm°C-O-叔丁基-L-谷氨酸

Fmoc-O-叔丁基-L-谷氨酸置于n,N'-二环己基碳二亚胺,三氟乙酸体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 2.5H,反应生成N-芴甲氧羰基-L-谷氨酸 1-烯丙基酯
参考文献:一种新颖,便捷的三维正交策略,用于固相合成环肽
标题:一种新颖,便捷的三维正交策略,用于固相合成环肽
摘要:从头到尾的环状肽是通过有效的三维正交固相策略(fmoc / T Bu /烯丙基)制备的,其特征是侧链锚定至pac或pal载体,选择性钯(o)催化的烯丙基去除,Bop / Hobt / Diea介导的与树脂结合的环化反应.
Doi:10.1016/0040-4039(93)85003-F

专利信息

专利号:US-2017320908-A1
优先权日:2014-11-19
标题 :Solid phase synthesis of cyclic amino acid molecules
发明人：HICKEY JENNIFER L; MANCUSO JOHN; MARSAULT ERIC; ROUGHTON ANDREW L; TREDER ADAM P; TREMBLEY MARIE-CLAUDE J; YUDIN ANDREI K; ZARETSKY SERGE
权利人:ENCYCLE THERAPEUTICS; GOVERNING COUNCIL OF THE UNIV OF TORONTO; UNIV SHERBROOKE
摘要:The present invention relates to cyclic amino acid molecules and methods of preparing the same, and in particular the macrocyclization of amino acids or linear peptides bound to a solid support.

专利号:US-12024537-B2
优先权日:2018-05-31
标题 :Compositions and methods for chemical synthesis
发明人：SEIFERT COLE
权利人:SEDERMA SA
摘要:The disclosure relates to chemical compositions that can include anchor molecules for chemical synthesis. GAP anchor molecules can include GAP constituents, linker constituents, and spacer constituents. Anchor molecules can be used to synthetically manufacture peptides. A novel method of solution-phase peptide synthesis is also disclosed that utilizes novel group-assisted purification protecting groups to facilitate efficient, scalable chemistry to synthetically manufacture peptides.

专利号:US-2025289851-A1
优先权日:2022-04-22
标 题:Cyclic peptides for delivering therapeutics
发明人：DOUGHERTY PATRICK; TOTARO KYLE A; DOMBROSKI AMANDA; GIESLER RILEY; ZHOU MING; STREETER MATTHEW; GOFFIN ALEC; QIAN ZIQING
权利人:ENTRADA THERAPEUTICS INC
摘要:The present disclosure relates to the synthesis of cyclic peptides that are able to effectively deliver cargo, e.g., a therapeutic moiety (TM), inside a cell to treat a variety of conditions and diseases.

专利号:EP-3221335-A1
优先权日:2014-11-19
标 题 :Solid phase synthesis of cyclic amino acid molecules

专利号:CA-2967750-A1
优先权日:2014-11-19
标题 :Solid phase synthesis of cyclic amino acid molecules

专利号:EP-1658282-B1
优先权日:2003-08-29
标题:Novel chelating agents and chelates and their use
发明人：HOVINEN JARI; MUKKALA VELI-MATTI; HAKALA HARRI; PEURALAHTI JARI
权利人:WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.