CAS: 140-80-7; 2-Amino-5-Diethylaminopentane

该化合物是一种有机化合物,其特征是其脂态矿体结构,其特点是氮原子的两个乙基组,这些组位于五碳链终端端,该化合物一般没有颜色,可粉色黄色液体,有独特的矿泉味,在水和有机溶剂中溶解,可应用于多种用途.N,N-Di乙-1,4-五溴二苯醚主要用作环氧树脂的固化剂,在聚合物配方中作为硬化剂使用,其化学特性包括由于有地雷功能组的存在而参与核分裂反应的能力,这些功能组也可以参与氢联结.安全考虑很重要,因为接触时可能会对皮肤,眼睛和呼吸系统产生刺激.建议在经过适当通风的地区进行适当处理和储存,以减轻与该化合物相关的健康风险.

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ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号105-14-6 5-二乙氨基-2-戊酮 | CAS号101881-56-5 bis-(4-diethyla... | CAS号39749-10-5 diethyl-(4-chlo... | CAS号5412-69-1 5-二乙基胺基-2-戊醇 | CAS号5426-96-0 (NZ)-N-(5-dieth... | CAS号32314-21-9 diethylamino-ac... | CAS号136571-69-2 5-diethylamino-... | CAS号67-56-1 甲醇 | CAS号7664-41-7 氨 | CAS号7647-01-0 盐酸 | CAS号2007-01-4 1,4-Pentanediam... | CAS号27228-62-2 1,4-Pentanediam... | CAS号3295-64-5 1,2,3,4-四氢啶 | CAS号1243-14-7 N-[5-(diethylam... | CAS号54-05-7 氯喹 | CAS号35471-59-1 5-diethylamino-... | CAS号109-89-7 二乙胺 | CAS号25844-57-9 1,4-Pentanediam... | CAS号74861-78-2 1-((4-(Diethyla...

合成工艺路线路线简述

    5-二乙氨基-2-戊酮置于氨,氢气体系中,化学反应 24.0H,以89%的收率获得2-氨基-5-二乙基氨基戊烷
    参考文献:合成关键中间体 Novoldiamine 和 Hydroxynovaldiamine 的可扩展工艺及其在氯喹,羟氯喹和 Mepacrine 合成中的应用
    标题:合成关键中间体 Novoldiamine 和 Hydroxynovaldiamine 的可扩展工艺及其在氯喹,羟氯喹和 Mepacrine 合成中的应用
    摘要:摘要 一种高效且可扩展的合成酚醛二胺和羟基酚醛二胺的工艺是由乙酰丙酸完成的,乙酰丙酸很容易从天然原料中获得.这些二胺被用作合成氯喹,羟氯喹和甲巴林的关键中间体.该过程涉及的关键步骤是乙酰丙酸与仲胺在1,1'-羰基二咪唑的辅助下偶联和肟-酰胺官能团的一锅还原得到相应的二胺.
    Doi:10.1080/00397911.2022.2061358

    海关参考信息

    专利信息


    专利号:US-4988806-A
    优先权日:1988-06-13
    标 题:Nitrogen-containing derivatives of carboxymethylcellulose, their synthesis and their use in cosmetic preparations
    发明人:GRUENING BURGHARD; HOFFMANN KLAUS; KOERNER GOETZ; KOLLMEIER HANS-JOACHIM
    权利人:GOLDSCHMIDT AG TH
    摘要:Derivatives of carboxymethylcellulose are disclosed in which all or a portion of the carboxymethyl groups are replaced by groups of the general formula in which R1 is a hydrogen or methyl group, R2 is a divalent aliphatic hydrocarbon group with 2 to 5 carbon atoms, R3, R4 are alkyl groups with 1 to 4 carbon atoms, R5 is an alkyl group with 1 to 4 carbon atoms or a benzyl group, X is a halogen or sulfate group or a sulfonic acid group, with the proviso that, on the average, at least 0.1 quaternary ammonium groups are contained per anhydroglucose unit of the polymeric molecule. The invention furthermore relates to derivatives of carboxymethylcellulose, in which all or a portion of the carboxymethyl groups are replaced by groups of the general formula in which the substituents R1, R2, R3 and R4 have the above meaning, with the proviso that, on the average, at least 0.1 tertiary amino groups are contained per anhydroglucose unit of the polymeric molecule, as intermediates for the synthesis of the aforementioned derivatives. The invention furthermore is directed to a method for the synthesis of the derivatives of carboxymethylcellulose and their use in cosmetic preparations, especially for the care of hair.

    专利号:US-5023246-A
    优先权日:1988-06-13
    标 题:Betaine group-containing derivatives of carboxymethylcellulose, their synthesis and their use in cosmetic preparations
    发明人:GRUENING BURGHARD; HOFFMANN KLAUS; KOERNER GOETZ; KOLLMEIER HANS-JOACHIM
    权利人:GOLDSCHMIDT AG TH
    摘要:Betain group-containing derivatives of carboxymethylcellulose are disclosed. They are characterized in that all or a portion of the carboxymethyl groups are or is replaced by groups of the general formula wherein R1 is hydrogen or methyl group, R2 is a divalent aliphatic hydrocarbon group with 2 to 5 carbon atoms, R3, R4 is an alkyl group with 1 to 4 carbon atoms, R5 is a divalent aliphatic hydrocarbon group with 1 to 10 carbon atoms, with the proviso that, on the average, at least 0.1 betaine groups are contained for each anhydroglucose unit of the polymeric molecule. Also, a method for the synthesis of these compounds and their use in cosmetic preparations, especially for the care of hair, are disclosed. In addition, novel derivatives of carboxymethylcellulose with tertiary amino groups are taught as intermediates. In these derivatives, all or a portion of these groups are or is replaced by groups of the general formula in which the substituents R1, R2, R3 and R4 have the above meaning, with the proviso that, on the average, at least 0.1 tertiary amino groups are contained per anhydroglucose unit of the polymeric molecule.

    专利号:US-4412075-A
    优先权日:1981-01-16
    标题 :Process for the preparation of quinolin-4-ones
    发明人:BAUDOUIN MICHEL; DESBOIS MICHEL
    权利人:RHONE POULENC SANTE
    摘要:1,2,3,4-Tetrahydroquinolin-4-ones of the formula: ##STR1## wherein R represents a hydrogen or halogen atom, an alkyl radical (1 to 4 carbon atoms), an alkoxy radical (1 to 4 carbon atoms) or the trifluoromethyl radical, and R 1 represents a hydrogen atom, an alkyl radical (1 to 4 carbon atoms) or the trifluoromethyl radical, are prepared by cyclizing a 3-anilinopropionic acid of the formula: ##STR2## (wherein R and R 1 are as hereinbefore defined) in a mixture of hydrofluoric acid and boron trifluoride. n The quinolinone products are useful intermediates in the synthesis of therapeutically active substances.

    专利号:US-2013102730-A1
    优先权日:2010-04-02
    标 题:Polyamine-containing polymers and methods of synthesis and use
    发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
    权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
    摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).

    专利号:WO-0053579-A2
    优先权日:1999-03-10
    标 题:Solid phase synthesis of 4-aminoproline derivatives and/or combinatorial libraries thereof

    专利号:US-6417195-B1
    优先权日:1999-02-22
    标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
    发明人:LEBL MICHAL
    权利人:LION BIOSCIENCE AG
    摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.
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    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 34.
    摘要:Scholz, U.; Dong, W.; Feng, J.; Shi, W., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 76.
    摘要:Adriaensen, K.; De Vos, D., Science of Synthesis, (2022) , 167.
    摘要:J. C. Gage. J. Chem. Soc. 1949, 1458.
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