N-Methyl-Thioformamid置于四丁基高碘酸铵体系中,用 二氯甲烷 用作溶剂,化学反应 0.75H,以86%的收率获得n-甲基甲酰胺 参考文献:Facile Desulfurization Of Thioamides And Thioureas With Tetrabutylammonium Periodate Under Mild Conditions 标题:Facile Desulfurization Of Thioamides And Thioureas With Tetrabutylammonium Periodate Under Mild Conditions 摘要:Thioamides And Thioureas Were Reacted With Tetrabutylammonium Periodate At Room Temperature To Afford The Corresponding Amides And Ureas,Respectively,Under Aprotic Conditions. Doi:10.1007/s00706-005-0289-8
专利号:US-9012625-B2 优先权日:2009-04-07 标 题 :Method for the synthesis of a trisaccharide 发明人:DÉKANY GYULA; Ã?GOSTON KÃ?ROLY; BAJZA ISTVAN; BOUTET JULIEN; BØJSTRUP MARIE; FANEFJORD METTE; PÉREZ FIGUEROA IGNACIO; HEDEROS MARKUS; HORVATH FERENC; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; OLSSON JOHAN; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS 权利人:DÉKANY GYULA; Ã?GOSTON KÃ?ROLY; BAJZA ISTVAN; BOUTET JULIEN; BØJSTRUP MARIE; FANEFJORD METTE; PÉREZ FIGUEROA IGNACIO; HEDEROS MARKUS; HORVATH FERENC; KOVÃ?CS-PÉNZES PIROSKA; KRÖGER LARS; OLSSON JOHAN; RÖHRIG CHRISTOPH; SCHROVEN ANDREAS; VRASIDAS IOANNIS; GLYCOM AS 摘要:The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates.
专利号:US-2012215002-A1 优先权日:2009-10-09 标 题:Synthesis of optically active intermediate for the preparation of montelukast 发明人:LEFORT LAURENT 权利人:LEFORT LAURENT 摘要:The present invention relates to the synthesis of optically active alcohols by means of enantioselective hydrogenation of ketones in biphasic systems. In particular the present invention relates to the synthesis of an optically active alcohol of general formula (1).
专利号:US-10253153-B2 优先权日:2015-04-24 标题 :Linker and support for solid phase synthesis of nucleic acid, and production method of nucleic acid using said support 发明人:MAETA ERI; MORI KENJIRO; HORIE SHOHEI; ITO TAKAHIKO; SAITO SHOICHIRO; NAGAO RYUHEI 权利人:NITTO DENKO CORP 摘要:The present invention provides a linker for solid phase synthesis of nucleic acid, which consists of a compound represented by the formula (I) or the formula (II), a support for solid phase synthesis of nucleic acid, which has a structure represented by the formula (III), and a production method of a nucleic acid, which uses the support: n nwherein each symbol is as defined in the SPECIFICATION.
专利号:US-10696622-B2 优先权日:2016-08-29 标题 :Synthesis of N-vinyl carboxylic acid amides 发明人:DUMOLEIJN KIM; MOONEN KRISTOF; Henricot Alexis; Han Cai Xing Simon 权利人:TAMINCO BVBA; EASTMAN CHEM CO 摘要:Processes and systems for producing N-vinyl carboxylic acid amides are provided herein. According to some aspects of the present invention, a process for producing an N-vinyl carboxylic acid amide is described that eliminates interim solids handling steps during formation of the intermediate compounds, thereby increasing efficiency and reducing cost. The processes and system described herein may be used for the synthesis of N-vinylformamide and its intermediates, including 1-hydroxyethylformamide and 1-alkoxyethylformamide, or for the synthesis of N-methyl,N-vinylformamide and its intermediates, including N-methyl,1-hydroxyethylformamide and N-methyl,1alkoxyethylformamide.
专利号:US-8252928-B2 优先权日:2008-09-16 标题:Processes for the synthesis of five and six membered heterocyclic rings 发明人:WANG PETER X; JIANG TAO; BERBERICH DAVID W 权利人:WANG PETER X; JIANG TAO; BERBERICH DAVID W; MALLINCKRODT LLC 摘要:The present invention provides processes for the synthesis of five and six membered rings. In particular, the present invention provides processes for the synthesis of five and six membered rings in alkaloids.
专利号:US-11999757-B2 优先权日:2017-11-01 标 题:Synthesis of boronate ester derivatives and uses thereof 发明人:BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J 权利人:MELINTA SUBSIDIARY CORP 摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.
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合成参考文献
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