CAS: 103-03-7; 2-Phenylhydrazinecarboxamide

该化合物是一种有机化合物,其特征是附于一个苯环的半碳氨功能组,一般是白色到白外晶状固体,以其在水中的中等溶性以及乙醇和丙酮等有机溶剂中的高溶性而著称.该化合物的分子配方为C8H10N4O,表明碳,氢,氮和氧原子的存在.该化合物主要用于有机合成,并作为试剂用于确定碳基化合物,形成稳定的半碳基.1-苯基-苯基甲酸酯具有类似有机化合物特征的熔点和沸点等特性,并可能发生各种化学反应,包括凝聚和替代.在处理该化合物时,应当采取安全防范措施,因为如果摄入或吸入,可能会对健康造成危害.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

3,5-dimethylpyrazole-1-carboxamide phenylhydrazine N-phenyl-N-nitrosourea acetone-(2-phenyl semicarbazone) 5-(3-nitro-phenyl)-1-phenyl-1,2-dihydro-[1,2,4]triazol-3-one 1,5-diphenyl-1,2-dihydro-[1,2,4]triazol-3-one 1-benzoyl-1-phenyl semicarbazide N,N'-dicarboxylic acid N'-amid-N-anilidephenyl-hydrazine-N,N'-dicarboxylic acid N'-amid-N-anilide

合成工艺路线路线简述

  • 合成目标产物 1-Phenylsemicarbazide 主要起始原料 Phenylurethane And 4-Fluorobenzhydrazide
  • (文献来源)合成步骤主要原料 Phenylurethane 和 4-Fluorobenzhydrazide
📜苯肼置于水,溶剂黄146体系中,化学反应生成1-苯基氨基脲
参考文献:Widman,Chemische Berichte,1893,Vol. 26,P. 2616
标题:Widman,Chemische Berichte,1893,Vol. 26,P. 2616

专利信息


专利号:US-3888844-A
优先权日:1971-09-10
标 题:Halogenated esters of phosphorus-containing acids (ii)
发明人:D ALELIO GAETANO F
权利人:ALELIO GAETANO F D
摘要:This invention deals with new phosphorus containing polymeric esters having pendent groups therein of the formula OBTAINED BY THE REACTION OF A POLYMER HAVING AT LEAST 2 AND PREFERABLY AT LEAST 4 HYDROXY GROUPS THEREIN WITH A PHOSPHORUSHALOGEN COMPOUND OF THE FORMULA XP(O) (ORCX CXR'')2 wherein: R represents a divalent hydrocarbon radical containing 1-20 carbon atoms; R'' represents X, hydrogen or R''''; R'''' represents a monovalent hydrocarbon radical containing 1-20 carbon atoms; and X represents chlorine or bromine. Somewhat related polymers are also disclosed as derived by the reaction of WHEREIN Q'' is an organic moiety, n'' has a value of at least one, n'''' is one or two, R'''''' represents hydrogen or a monovalent hydrocarbon group of 1-20 carbon atoms, and the other symbols have the same meaning as defined above. Also disclosed are the reaction products of the phosphite compound HOP(ORCX CXR'')2 with an aldehyde and an organic nitrogen compound having one or two hydrogen atoms on the nitrogen, or with a compound having an ethylenic group therein. These new ester polymers and compounds are useful particularly as fire retardants, agricultural chemicals, fuel additives, plasticizers, monomers and intermediates for the synthesis of other useful derivatives.

专利号:US-3985835-A
优先权日:1973-07-30
标题 :Halogenated esters of phosphorus-containing acids
发明人:D ALELIO GAETANO F
权利人:ALELIO GAETANO F D
摘要:This invention deals with new phosphorus-containing esters having the formula R'''2NP(O) (ORCX=CXR')2 wherein X represents Cl or Br; R represents a divalent hydrocarbon radical of 1-20 carbon atoms; R' represents H, X or R''; R'' represents a monovalent hydrocarbon radical of 1-20 carbon atoms; R''' represents hydrogen, a monovalent hydrocarbon radical of 1-20 carbon atoms, a divalent saturated aliphatic hydrocarbon group having 5 carbon atoms between valencies and forming a cyclic structure with the N, or a derivative of said monovalent hydrocarbon radical in which the derivative group is hydroxy, NH2, NHR'', NR''2, -NR''''K, R''''NHNHC(O)-, R''''NHC(O)NH-, -(N-R-)n-NR'''' , ¦¦ KK R''COO-, R''CONH- or R''O, R'''' represents hydrogen or R''; n represents an integer having a value of 0-50; and K represents hydrogen, R'' or -P(O) (ORCX=CXR')2. These new esters are useful particularly as fire retardants, agricultural chemicals, fuel additives, plasticizers, monomers and intermediates for the synthesis of other useful derivatives.

专利号:US-3886237-A
优先权日:1971-09-10
标题 :Halogenated phosphonates
发明人:D ALELIO GAETANO F
权利人:ALELIO GAETANO F D
摘要:This invention deals with new phosphorus-containing esters having the formula AND DERIVATIVES THEREOF OBTAINED BY REACTION WITH AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATTACHED TO THE NITROGEN OF THE AMINE, WHEREIN R represents a divalent hydrocarbon radical containing 1-20 carbon atoms; R'' represents X, hydrogen or R''''; R'''' represents a monovalent hydrocarbon radical containing 1-20 carbon atoms; and X represents chlorine or bromine. These new esters are useful particularly as fire retardants, agricultural chemicals, fuel additives, plasticizers, monomers and intermediates for the synthesis of other useful derivatives.

专利号:CN-116375608-A
优先权日:2022-12-29
标题:Synthesis of phenylsemicarbazone and identification of iron ions by phenylsemicarbazone

专利号:CN-115974728-B
优先权日:2022-12-29
标 题 :Synthesis of phenylsemicarbazone and identification of hexavalent chromium ions by phenylsemicarbazone

专利号:CN-102936222-A
优先权日:2012-11-20
标 题 :Synthesis and Application of Pyrazolone Thermochromic Compounds

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis Of Nitrogen‐containing Goniothalamin Analogues With Higher Cytotoxic Activity And Selectivity Against Cancer Cells
作者:Matheus A. Meirelles,Carolyne B. Braga,Catia Ornelas,Ronaldo A. Pilli |发布日期:2019.8.6
摘要:Goniothalamin Analogues Displaying Nitrogen‐containing Groups Were Designed And Synthesized. A Total Of 19 Novel Analogues Were Evaluated Against A Panel Of Four Different Cancer Cell Lines, Along With The Normal Prostate Cell Line Pnt2 To Determine Their Selectivity. Among Them, Goniothalamin Chloroacrylamide 13 E Displayed The Lowest Ic50 Values For Both Mcf‐7 (0.5 μm) And Pc3 (0.3 μm) Cells, About 26‐fold

合成参考文献


参考文献:10.1039/c1pp05110e
摘要:Yuan H, Guo J, Jia D, Guo M, Liu L, Wu D, Li F. Photochromism of a pyrazolone derivative in crystalline state and in HPMC composite film. Photochemical & Photobiological Sciences. 2011 Oct;10(10):1562–7. doi: 10.1039/c1pp05110e.
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