CAS: 870718-07-3; 3-Benzyloxy-2,6-Difluorophenylboronic Acid
该化合物是一种有机体化合物,其特点是存在一种碱性酸功能组,众所周知,该组能够与二醇形成可逆的共价结合,从而在包括有机合成和药用化学在内的各种应用中发挥作用.该组具有二氟联苯共振特性,可增强它的电子特性并影响它的再活性和溶性.苯氧基组有助于分子的整体稳定性和脂性,有可能改善它在制药方面的生物利用率.该组通常用于交叉反应,例如铃木-米亚鲁交织,这是在复合有机分子合成中形成碳-碳联结的关键方法.其独特结构允许选择性的再活动,使它成为各种化学实体发展的宝贵中间体.和许多碳酸一样,必须谨慎地处理这一化合物,因为它对水和空气具有敏感性,可能影响其稳定性和再活性.
- 英文名称3-Benzyloxy-2,6-Difluorophenylboronic Acid
- 中文名称3-苄氧基-2,6-二氟苯硼酸
- IUPAC名称(3-(benzyloxy)-2,6-difluorophenyl)boronic acid
- 其它别名3-苄氧基-2,6-二氟苯基硼酸; [3-(Benzyloxy)-2,6-Difluorophenyl]Boronic Acid
- CAS编号870718-07-3
- MFCD编号:MFCD06200705
- EINECS号:874-611-3
- 分子式:C13H11BF2O3分子量:264.04
- 产品CID: 1875444
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2905110000-甲醇
2906210000-苄醇
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
