CAS: 7418-19-1; 2,2,5,5-Tetramethyl-2,5-Disila-1-Azacyclopentane

相似化合物

17882-94-9 14579-90-9 2117-18-2

上下游产品

1,2-bis-(chlorodimethylsilyl)ethane 1,2-bis(dimethylsilyl)ethane trimethylphosphane 1-methyl-3-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentyl)-4-phenyl-2-azetidinone

📜1,2-双(氯二甲基硅基)乙烷置于氨体系中,用 乙醚 作为反应溶剂,以57%的收率获得产物2,2,5,5-四甲基-2,5-二硅基-1-杂氮环戊烷
参考文献:Hosomi,Akira; Kohra,Shinya; Tominaga,Yoshinori,Chemical And Pharmaceutical Bulletin,1988,Vol. 36,P. 2342-2345
标题:Hosomi,Akira; Kohra,Shinya; Tominaga,Yoshinori,Chemical And Pharmaceutical Bulletin,1988,Vol. 36,P. 2342-2345

专利信息

专利号:US-8431712-B2
优先权日:2004-02-09
标 题 :Methods for the synthesis of pyridoxamine
发明人：KHALIFAH RAJA G; KEILITZ ROLAND; KOELLNER CHRISTOPH; DEGENHARDT THORSTEN; BRAND STEPHEN ROBERT
权利人:KHALIFAH RAJA G; KEILITZ ROLAND; KOELLNER CHRISTOPH; DEGENHARDT THORSTEN; BRAND STEPHEN ROBERT; NEPHROGENEX INC
摘要:The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): n nand salts thereof.n nThe invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.

专利号:EP-0442576-A1
优先权日:1990-02-13
标 题:Synthesis of cis-beta-lactams with the aid of an alkali metal compound
发明人：VAN KOTEN GERARD; VAN DER STEEN FREDERIK HENDRIK; JASTRZEBSKI JOHANN TONNS BARTH; KLEIJN HENK
权利人:UNIV UTRECHT
摘要:A synthesis of cis -β-lactams in a nearly quantitative yield by a condensation reaction of an alkali metal enolate, a substituted glycine ester and an alkali metal base, with an activated imine, is provided.

专利号:US-2025206743-A1
优先权日:2022-03-25
标 题:Tyk2 inhibitor synthesis and intermediates thereof
发明人：MASSE CRAIG E; PHADKE AVINASH S; LAWSON JON P; LEVY STUART; YANG XIAOWEI; WU GUISHENG; FAN SHUFENG
权利人:TAKEDA PHARMACEUTICALS CO
摘要:Described herein are methods of synthesis of a tyrosine-protein kinase 2 (TYK2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. Also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.

专利号:US-2025197439-A1
优先权日:2022-03-18
标 题:Decarboxylative acetoxylation using mn(ii) or mn(iii) reagent for synthesis of 4'-acetoxy-nucleoside and use thereof for synthesis of corresponding 4'-(dimethoxyphosphoryl)methoxy-nucleotide
发明人：VAGLE KURT EDRIC; BHADURI SAYANTAN; YANG GUOHAN
权利人:DICERNA PHARMACEUTICALS INC
摘要:The present invention relates to the preparation of nucleic acids, nucleosides, nucleotides, and analogues thereof useful as potent and stable RNA interference agents. The present invention provides improved yields and avoids the use of lead tetraacetate for decarboxylative acetylation which decreases the overall cost of production by removing the need for lead remediation and offers a significant reduction in the environmental costs in production.

专利号:US-8268936-B2
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

专利号:US-2012196989-A1
优先权日:2005-02-11
标题:Synthesis of homopolymers and block copolymers
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.