CAS: 6436-62-0; Isoxazole-4-Carboxylic Acid

相似化合物

102790-36-3 80370-40-7 65373-53-7

上下游产品

CAS号80370-40-7 4-异噁唑甲酸乙酯 | CAS号6455-40-9 4-溴甲基异噁唑 | CAS号62348-15-6 1,2-oxazole-4-c...

专利信息

专利号:US-5086182-A
优先权日:1985-04-12
标题:Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
发明人：VYAS DOLATRAI M; SKONEZNY PAUL M
权利人:BRISTOL MYERS CO
摘要:There is provided a novel and efficient stereoselective total synthesis of epiodophyllotoxin and related epipodophyllotoxin compounds of the general formula wherein R1 and R2 are independently hydrogen or (lower)-alkoxy, or R1 and R2, taken together, is methylenedioxy; R4 and R6 each are independently hydrogen or (lower) alkoxy; and R5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present invention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents.

专利号:US-4728740-A
优先权日:1985-04-12
标 题:Intermediates for the production of epipodophylotoxin and related compounds and processes for the preparation and use thereof
发明人：VYAS DOLATRAI M; SKONEZNY PAUL M
权利人:BRISTOL MYERS CO
摘要:There is provided a novel and efficient stereoselective total synthesis of epipodophyllotoxin and related epipodophyllotoxin compounds of the general formula wherein R1 and R2 each are independently hydrogen or (lower)alkoxy, or R1 and R2, taken together, is methylenedioxy; R4 and R6 each are independently hydrogen or (lower)alkoxy; and R5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present invention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents.

专利号:US-5011948-A
优先权日:1985-04-12
标 题:Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
发明人：VYAS DOLATRAI M; SKONEZNY PAUL M
权利人:BRISTOL MYERS CO
摘要:There is provided a novel and efficient stereoselective total synthesis of epipodophyllotoxin and related epipodophyllotoxin compounds of the general formula wherein R1 and R2 each are independently hydrogen or (lower)alkoxy, or R1 and R2, taken together, is methylenedioxy; R4 and R6 each are independently hydrogen or (lower)alkoxy; and R5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present invention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents.

专利号:US-5120862-A
优先权日:1985-04-12
标 题:Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
发明人：VYAS DOLATRAI M; SKONEZNY PAUL M
权利人:BRISTOL MYERS CO
摘要:There is provided a novel and efficient stereoselective total synthesis of epipodophyllotoxin and related epipodophyllotoxin compounds of the and present invention wherein R1 and R2 each are independently hydrogen or (lower)alkoxy, or R1 ll and R2, taken together, is methylenedioxy; R4 and R6 each are independently hydrogen or (lower)alkoxy; and R5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present ivnention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents.

专利号:CN-104725329-A
优先权日:2015-01-13
标题:A kind of isoxazole carboxylic acid compound with antitumor activity and its synthesis method

专利号:CN-104803934-B
优先权日:2015-05-04
标 题:A kind of phenylisoxazole carboxylic acid compound with antitumor activity and its synthesis method and application