CAS: 628-99-9; 2-Nonyl Alcohol

该化合物是一种属于非氨醇异构体类别的手性酒精,其特点是长碳链,由9个碳原子组成,与第二个碳相连,具有氢氧基(OH)功能组.该化合物一般是一种无色液体,具有舒适,脂肪味,在香味和口味行业有用.其分子式为C9H20O,其挥发性相对较低,有助于其各种应用的稳定性.2-诺诺醇在有机溶剂中溶解,但由于其水性碳链,在水中溶性有限.该化合物显示出典型的酒精特性,包括参与氢结合的能力,影响其沸点和熔点.此外,它可以氧化成相应的keton或 aldehydes,使其在有机合成中成为具有多种特性的中间体.在处理该物质时,应当注意安全防范措施,因为与皮肤或眼睛接触时可能会引起刺激.

结构式图片

相似化合物

821-55-6 123-96-6 1653-30-1

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

methyl magnesium iodide °Ctanal 2-Nonanone methylmagnesium bromide 2-bromononane 2-nonene 2-Nonanone 2-nonanyl acetate

合成工艺路线路线简述

    2-壬酮置于氢氧化钾,Gold On Titanium Oxide,异丙醇体系中,化学反应 8.0H,反应生成 2-壬醇
    参考文献:在转移加氢条件下,用负载型金催化剂高效,化学选择性地还原羰基化合物.
    标题:在转移加氢条件下,用负载型金催化剂高效,化学选择性地还原羰基化合物.
    摘要:一种新型的非均相催化转移加氢(cth)系统,由不易燃的负载au催化剂和2-丙醇作为氢供体组成,已被证明可有效地将多种芳香族酮和醛化学选择性还原为相应的芳香族酮和醛.酒精.
    DOI:10.1039/b807608A

    海关参考信息

    专利信息


    专利号:US-7247752-B2
    优先权日:2004-10-01
    标 题 :Methods for the synthesis of astaxanthin
    发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
    权利人:CARDAX PHARMACEUTICALS INC
    摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

    专利号:US-2004018598-A1
    优先权日:2000-05-30
    标题 :Bio-intermediates for use in the chemical synthesis of polyketides
    发明人:SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
    摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKSâ€?) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediatesâ€?) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.

    专利号:WO-2015193910-A1
    优先权日:2014-06-20
    标题:Asymmetric synthesis of 2-substituted indolines and 3-substituted cinnolines
    发明人:KUMAR BOOPATHY SENTHIL; SUDALAI ARUMUGAM
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention relates to a novel one step proline catalyzed process for synthesis of chiral hydrazine and its derivatives from o-bromo hydro cinamaldehyde. Further, it relates to a novel one step process for the synthesis of substitued indolines and cinnolines from chiral hydrazines and its derivatives.

    专利号:US-7368568-B2
    优先权日:2001-08-03
    标 题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use
    发明人:WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
    权利人:BAYER SCHERING PHARMA AG
    摘要:The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroarnides for the synthesis of edothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

    专利号:US-6384228-B2
    优先权日:1998-05-26
    标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof
    发明人:NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO
    权利人:NIHON MEDIPHYSICS CO LTD
    摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.

    专利号:US-8507562-B2
    优先权日:2004-07-07
    标 题 :Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof
    发明人:HUANG LAN
    权利人:HUANG LAN; HYWE PHARMACEUTICALS INC
    摘要:The present invention provides convergent processes for preparing (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, and (−)-beta-elemene fluoride and analogues thereof. Also provided are intermediates useful for preparing (−)-beta-elemene. The present invention further provides novel compositions based on analogues of (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride and methods for the treatment of cancer, such as brain tumor, lung cancer, breast cancer, prostate cancer, ovarian cancer, colorectal cancer, gastric intestional cancer, and stomach cancer. n The inventors propose a combination therapy using 1) one or more of the following anti-cancer agents: including, but not limited to, Cisplatin, 5-FU, Taxol, Taxol derivatives, and any anti-cancer agent, and 2) one or more of the following (−)-beta-elemene and its analogs, including (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride, and their analogs, and (−)-beta-elemene's intermediate in its chemical synthesis, for the treatment of cancer, especially for the treatment of brain tumor, lung cancer, ovarian cancer, bladder cancer, cervical cancer, colon cancer, breast cancer, and prostate cancer.
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    主要参考文献

    [参考文献]: Fabien Démares, Et Al. Differential Involvement Of Glutamate-Gated Chloride Channel Splice Variants In The Olfactory Memory Processes Of The Honeybee Apis Mellifera. Pharmacol Biochem Behav. 2014 Sep:124:137-44.

    合成参考文献


    参考文献:10.1107/s1600536811008257
    摘要:Hussen RSD, Heidelberg T, Rodzi NZM, Ng SW, Tiekink ERT. 4-Formylphenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside. Acta Crystallogr E Struct Rep Online. 2011 Mar 09;67(4):o826. doi: 10.1107/s1600536811008257.
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