专利号:US-6235944-B1 优先权日:1999-01-21 标 题:Production of secondaryalkoxy-1-alkenes 发明人:JOHN THOMAS V; SUBRAMANIAM CHITOOR S; WANG ZHENG; KUCERA JR RICHARD J 权利人:CREANOVA INC 摘要:The present invention relates to a general synthesis for producing secondaryalkoxy-1-alkenes in commercial quantities in good yields by reacting cyclic and acyclic ketones and the corresponding alcohol with a secondary alkyl orthoformate ester in the presence of an acid catalyst, a Lewis acid, ferric chloride being preferred, and recovering the produce as a liquid of high purity.
专利号:US-4990602-A 优先权日:1986-12-17 标 题:Erythromycin A derivatives 发明人:MORIMOTO SHIGEO; ADACHI TAKASHI; MATSUNAGA TOHRU; KASHIMURA MASATO; ASAKA TOSHIFUMI; WATANABE YOSHIAKI; SOTA KAORU; SEKIUCHI KAZUTO 权利人:TAISHO PHARMACEUTICAL CO LTD 摘要:Erthromycin A derivatives represented by the general formula ##STR1## wherein R 1 is a group of the formula R 7 CH 2 -- (wherein R 7 is a hydrogen group or a lower alkyl group) or a group of the formula R 8 O-- (wherein R 8 is a lower alkyl group), R 2 is R 8 , a cycloalkyl group, a phenyl group or an aralkyl group.), or R 2 and R 7 together form an alkylene group, R 3 is a hydrogen atom, a lower alkyl group, a phenyl group or an aralkyl group, or R 3 and R 7 together form an alkylene group, or R 2 and R 3 together form an alkylene group, R 4 is a lower alkyl group, R 5 is a substituted silyl group, and R 6 is a hydrogen atom or R 5 , are disclosed. These compounds are useful as intermediates for the synthesis of antibacterial agents.
参考标题:An Efficient Synthesis Of Ketone Enol Ethers Mediated ByN-(1-Alkoxyalkyl)Benzotriazoles 作者:Alan R. Katritzky,Shibli I. Bayyuk,Stanislaw Rachwal 摘要:A New General Method For The Transformation Of Ketones Into Their Enol Ethers In Good Yield Is Developed Via Elimination Of Benzotriazole From N-(1-Alkoxyalkyl)Benzotriazole Intermediates.