CAS: 5445-17-0; Methyl 2-Bromopropanoate

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20047-41-0 32644-15-8 598-18-5

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CAS号27871-49-4 L-乳酸甲酯 | CAS号67-56-1 甲醇 | CAS号598-72-1 2-溴丙酸 | CAS号563-76-8 2-溴丙酰溴 | CAS号79-03-8 丙酰氯 | CAS号7148-74-5 2-溴丙酰氯 | CAS号67-56-1 甲醇 | CAS号598-72-1 2-溴丙酸 | CAS号595-37-9 2,2-二甲基丁酸 | CAS号940-31-8 2-苯氧基丙酸 | CAS号51338-27-3 禾草灵 | CAS号17639-93-9 2-氯丙酸甲酯 | CAS号20609-71-6 3-溴-2-甲基丙酸甲酯 | CAS号199384-57-1 (2-bromo-1-meth... | CAS号554-12-1 丙酸甲酯 | CAS号17422-12-7 2-甲基-3-氧代戊酸甲酯

L-乳酸甲酯置于甲基磺酰氯,三乙胺,Lithium Bromide体系中,用 二氯甲烷,四氢呋喃 作为反应溶剂,化学反应 2.0H,以74%的收率获得产物2-溴丙酸甲酯
参考文献:在温和条件下通过相应的磺酸盐从烷醇中制备伯烷基卤和仲烷基卤的有效方法
标题:在温和条件下通过相应的磺酸盐从烷醇中制备伯烷基卤和仲烷基卤的有效方法
摘要:该研究本文中所呈现显示,磺酸盐/卤化物交换可以有利地在thf中,当反应是由具有一个c手性烷基磺酸盐或衬底进行执行,以避免几副反应,例如消除和差向异构化 ħ酸性手性中心.发现该方法的主要限制是仲烷基磺酸盐向烷基氯化物的转化.在这种情况下,加入催化量的氯化锰明显加快了反应速度和效率.
DOI:10.1002/adsc.201100736

专利信息

专利号:US-4288608-A
优先权日:1978-06-01
标题:Synthesis of anthracyclines
发明人：JOHNSON FRANCIS; KIM KYOUNG S
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivitive adriamycin.

专利号:US-6610802-B2
优先权日:2001-05-29
标题 :Process for synthesis of polymer compositions, polymer compositionS obtainable by the process, and use of the same
发明人：ROOS SEBASTIAN; EISENBERG BORIS; HARPE CAROLIN
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to a process for synthesis of polymer compositions with reduced catalyst content, wherein ethylenically unsaturated monomers containing less than 0.5 wt % of ethylenically unsaturated monomers with at least one carboxylic group, sulfonic acid group and/or at least one phosphonic acid group relative to the total weight of the ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts and, after the polymerization, the catalyst contained in the polymer is at least partly separated. For this purpose, the polymer composition is filtered, after the polymerization, in the presence of at least one filter aid which contains at least 0.5 wt %, relative to the total weight of the filter aid, of repeating units that contain at least one carboxylic acid group, sulfonic acid group and/or at least one phosphonic acid group.

专利号:US-6610801-B1
优先权日:2000-11-13
标题:Processes for synthesis of polymer compositions
发明人：SCHERER MARKUS
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to processes for synthesis of poly(meth)acrylate compositions, wherein ethylenically unsaturated monomers are transformed to polymers by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, wherein ethylenically unsaturated monomers containing 50 to 100 wt %, relative to the total weight of ethylenically unsaturated monomers, of (meth)acrylates of formula (I) are polymerizedwherein R denotes hydrogen or methyl, R1 denotes a straight-chain or branched alkyl group with 8 to 40, carbon atoms, R2 and R3 independently denote hydrogen or a group of the formula -COOR1, wherein R' denotes hydrogen or a straight-chain or branched alkyl group with 8 to 40, carbon atoms, in the presence of copper, the total concentration of copper of oxidation numbers (I) and (II) in the polymerization composition being <=200 ppm relative to the total weight of the composition.

专利号:US-6639029-B1
优先权日:2000-11-13
标 题 :Process for continuous synthesis of polymer compositions as well as use of same
发明人：SCHERER MARKUS; BOLLINGER JOSEPH MARTIN; COOPER JR DAVID J; TILLERY LARRY STEPHEN; WOODRUFF ROBERT
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to a process for synthesis of polymer compositions, wherein ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable atom or group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, the process being characterized in that the polymerization takes place by means of continuous process operation.

专利号:US-12053529-B2
优先权日:2018-08-01
标题:Amino-reactive positively charged ATRP initiators that maintain their positive charge during synthesis of biomacro-initiators
发明人：RUSSELL ALAN J; MURATA HIRONOBU
权利人:UNIV CARNEGIE MELLON
摘要:Provided herein are materials and methods that include utilizing atom transfer radical polymerization (ATRP) initiator molecules that maintain a positive charge during biomacro-initiator synthesis.

专利号:US-5013412-A
优先权日:1989-04-28
标题:Process for the electrosynthesis of a beta,gamma-unsaturated ester
发明人：CONAN ANNIE; D INCAN ESTHER; PERICHON JACQUES; SIBILLE SOLINE
权利人:POUDRES ET EXPLOSIES SNPE SOC
摘要:The invention relates to a process for the electrosynthesis of a beta,gamma-unsaturated ester by electrolysis, in a cell having only a single compartment, of a mixture of an alpha,beta-unsaturated halide and an alpha-halogenated ester in the presence of an amount which is less than the stoichiometric amount for the reaction between the halide and the ester of a catalyst based on nickel complexed with a binitrogenous bidentate organic ligand. The anode, which is consumed by the electrochemical reaction of which it is the center, is made of a metal chosen from the group comprising the reducing metals and their alloys and is preferably made of zinc, aluminum or magnesium. This process, which is simple and economical, in particular permits the synthesis of arylacetates and arylpropionates, which are intermediates in the synthesis of pharmaceutical or plant protection products.