CAS: 54314-85-1; [3-(Benzyloxy)Propyl]Triphenylphosphonium Bromide

上下游产品

1-[(3-bromopropoxy)methyl]-benzene triphenylphosphine 3-benzyloxypropan-1-ol -3.3-dimethylcyclobutane-1α-carboxylic Acid2α-6-(Benzyloxy)-3-methyl-3-hexenyl-3.3-dimethylcyclobutane-1α-carboxylic Acid methyl 8-benzyloxy-3,3-dimethyl-5-°Ctenoate benzenonaphthacene1,15-bis(4-(phenylmethoxy)-1-butenyl)-5,12-dihydro-5,121',2'benzenonaphthacene

3-苄氧基-1-丙醇置于甲基磺酰氯,三乙胺,Lithium Bromide体系中,用 甲苯 作为反应溶剂,化学反应 13.5H,反应生成 (3-苄氧基丙基)三苯基溴化鏻
参考文献:无环非对映选择作为类苦参素的合成途径:基于克莱森重排的布鲁斯汀策略
标题:无环非对映选择作为类苦参素的合成途径:基于克莱森重排的布鲁斯汀策略
摘要:La Synthese De La Bruceantine(-) Pourrait S'Effectuer A Partir D'Un Acide Oxo-3 Perhydronaphtoique
DOI:10.1021/ja00295A027

专利信息

专利号:US-2001024798-A1
优先权日:1998-06-11
标题:Biomimetic combinatorial synthesis
发明人：SHAIR MATTHEW D; LINDSLEY CRAIG W; PELISH HENRY E; SHEEHAN SCOTT M; GOESS BRIAN C; LAYTON MARK E; CHAN LAWRENCE K; CHEN CHUO; WESTWOOD NICHOLAS J
摘要:The present invention provides biomimetic compounds and libraries thereof, as well as methods for their production. In general, the inventive method involves the selection of a desired biological synthetic pathway and mimics that synthetic pathway utilizing modern synthetic tools. The structures formed from this method are preferably generated in fewer than four steps. These scaffold structures can then be functionalized to yield biomimetic compounds and libraries of compounds. In preferred embodiments, biomimetic compounds and libraries are generated from an oxidative phenolic coupling reaction. In other particularly preferred embodiments, the compounds and libraries of compounds are generated from cascade reactions to yield bicyclo [n. 3.1 ] ring systems, medium ring systems, and fused ring systems. In addition to compounds, libraries and methods for their production, the present invention also provides pharmaceutical compositions and methods and kits for determining one or more biological activities of the library members.