CAS: 49863-47-0; (2R,3S,4R,5R,6S)-5-Amino-6-(((1R,2S,3S,4R,6S)-4,6-Diamino-3-(((2R,3R,4R,5R)-3,5-Dihydroxy-5-Methyl-4-(Methylamino)Tetrahydro-2H-Pyran-2-yl)Oxy)-2-Hydroxycyclohexyl)Oxy)-2-((R)-1-Hydroxyethyl)Tetrahydro-2H-Pyran-3,4-Diol

化学文摘社编号为498663-47-00..遗传物质对食堂细胞特别有效,使它成为选择含有新菌抗性基因的颗粒体的转基因细胞的宝贵工具.复合物抑制蛋白合成,导致细胞在非抗性细胞中死亡.遗传物质通常在细胞培养中使用,其浓度不同,取决于细胞类型和具体试验条件.必须谨慎地处理遗传物质,因为如果不适当使用,对目标细胞和非目标细胞都会有毒.此外,其在水溶液中的稳定性和溶解性使其适合各种实验室应用.

结构式图片

上下游产品

链霉素 Streptomicin 57-92-1

合成工艺路线路线简述

    📜,Lipofectamine,,Penicillin G Potassium,链霉素,G418 Disulfate 以to Obtain A Stable,G418-Resistant Strain的收率获得产物遗传霉素
    参考文献:2H-Chromene Compound And Derivative Thereof
    标题:2H-Chromene Compound And Derivative Thereof
    摘要:提供了一种2H-色烯化合物或其衍生物,具有优异的s1P1激动剂作用.该2H-色烯化合物或衍生物特别适用于预防和/或治疗由不良淋巴细胞浸润引起的疾病或由细胞异常增殖或堆积引起的疾病.

    专利信息


    专利号:EP-0386563-B1
    优先权日:1989-03-09
    标 题:Antisense-oligonucleotides for inhibiting the transactivator target sequence (TAR) and the synthesis of the transactivator protein (Tat) of HIV-I, and their use
    发明人:STROPP UDO DR; BAUMGARTEN JOERG DR; LOEBBERDING ANTONIUS DR; SPRINGER WOLFGANG DR; PIEL NORBERT DR; KRETSCHMER AXEL DR; KOELBL HEINZ DR Z ZT MOBAY COR; FROMMER WERNER PROF DR
    权利人:BAYER AG
    摘要:The present invention relates to chemically modified antisense oligonucleotides for inhibiting the transactivator target sequence (TAR) and the synthesis of the transactivator protein (tat) of HIV-1 and to the use thereof in pharmaceuticals. The chemically modified antisense oligonucleotides have antiviral effects. The pharmaceuticals can be used for the therapy of HIV infections. The antisense oligonucleotides are suitable as gene probes for detecting HIV.

    专利号:WO-0012554-A1
    优先权日:1998-08-28
    标题:Method for marked chemokine synthesis, marked chemokine and analysis kit
    发明人:VITA CLAUDIO; VIZZAVONA JEAN; GLUCKMAN JEAN CLAUDE; BENJOUARD ABDELAZIZ
    权利人:COMMISSARIAT ENERGIE ATOMIQUE; UNIV PARIS CURIE; VITA CLAUDIO; VIZZAVONA JEAN; GLUCKMAN JEAN CLAUDE; BENJOUARD ABDELAZIZ
    摘要:The invention concerns a method for the homogeneous synthesis of a marked chemokine in a specific position. The invention also concerns a chemokine obtained by said method, a composition and a kit comprising said chemokine. The invention is characterised in the method for the synthesis of the marked chemokine comprises a step which consists in a solid phase chemical synthesis of the chemokine or a modified sequence thereof.

    专利号:US-7411003-B1
    优先权日:2007-07-09
    标 题:Inhibition of Hepatitis B virus by cyclohexenone compounds from Antrodia camphorata
    发明人:LIU SHENG-YUN; KUO MAO-TIEN; WEN WU-CHE
    权利人:GOLDEN BIOTECHNOLOGY CORP
    摘要:The present invention relates to a compound of Antrodia camphorata used to inhibit HBV, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated from Antrodia camphorata, and its use in inhibiting HBV effectively. The cyclohexenone compound according to the present invention showed cytotoxicity on HBV-secreting human hepatoma cell line HepG2 2.2.15, decreased synthesis of HBV particles, further inhibited synthesis of HbsAg and HbeAg effectively to achieve the goal of HBV inhibition.

    专利号:US-7700332-B1
    优先权日:1999-05-21
    标 题:Methods for the synthesis of lactic acid using crabtree-negative yeast transformed with the lactate dehydrogenase gene
    发明人:RAJGARHIA VINEET; HATZIMANIKATIS VASSILY; OLSON STACEY; CARLSON TING; STARR JOHN N; KOLSTAD JEFFREY J; EYAL AHARON
    权利人:CARGILL INC
    摘要:The invention provides methods and materials related to the production of lactic acid. Specifically, the invention provides methods for producing lactic acid using a crabtree-negative yeast, such as of the Kluyveromyces, Pichia, Candida, Trichosporon and Yamadazmya genera, which have been transformed with a lactate dehydrogenase gene.

    专利号:US-8007994-B2
    优先权日:1998-12-10
    标题:Compositions and methods of modulating cholesterol metabolism
    发明人:MANGELSDORF DAVID J; REPA JOYCE J; TURLEY STEPHEN D; DIETSCHY JOHN M
    权利人:UNIV TEXAS
    摘要:The present invention relates to compositions and methods for reducing cholesterolemia and its effects. More specifically, the invention is directed, in one embodiment, to methods for screening for compounds that affect cholesterol levels generally, and in particular, that affect the absorption of cholesterol. The invention also is directed to methods of screening for compounds that increase bile acid synthesis. In so doing, the inventors describe useful transgenic cells and animals which lack one or both alleles of the LXRα gene. Also provided are therapeutic methods designed to reduce cholesterol levels in suitable subjects. The reduction may be effected by decreasing cholesterol absorption, increasing bile acid synthesis, or combinations thereof. Particularly useful in decreasing cholesterol absorption are RXR agonists, for example, rexinoid compounds. Therapeutic intervention in cholesterol biosynthesis and diet are additional adjunct therapies. In addition, the present invention relates to candidate compounds that modulate the expression of ABC-1 in a cell that expresses RXR. Methods of identifying and making a modulator of ABC-1 are disclosed.

    专利号:US-2013102730-A1
    优先权日:2010-04-02
    标 题:Polyamine-containing polymers and methods of synthesis and use
    发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN
    权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES
    摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:CRC Handbook of Antibiotic Compounds, Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980, 1(177), 1980
    参考文献:10.1021/jm060288o
    摘要:Yang G, Trylska J, Tor Y, McCammon JA. Binding of aminoglycosidic antibiotics to the oligonucleotide A-site model and 30S ribosomal subunit: Poisson-Boltzmann model, thermal denaturation, and fluorescence studies. J Med Chem. 2006 Sep 07;49(18):5478–90. doi: 10.1021/jm060288o.
    参考文献:10.1128/aac.01444-09
    摘要:Toth M, Frase H, Chow JW, Smith C, Vakulenko SB. Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. Antimicrob Agents Chemother. 2010 Apr;54(4):1590–5.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知