CAS: 41789-95-1; 1-(3-Methoxyphenyl)-N-Methylmethanamine

上下游产品

methylamine hydr°Chloride 3-methoxy-benzaldehyde methylamine 1-bromomethyl-3-methoxybenzene (3-methoxy-benzyl)-(4-methoxy-benzyl)-methyl-amine 2-[(3-Methoxy-benzyl)-methyl-amino]-6,6-dimethyl-4-oxo-cyclohex-2-enecarbonitrile N-methyl-3-methoxybenzylammonium chloride N-nitroso-N-(3-methoxybenzyl)methylamine

3-甲氧基溴苄置于palladium On Activated Charcoal 氢气体系中,用 四氢呋喃,甲苯 作为反应溶剂,化学反应生成 N-甲基-3-甲氧基苄胺
参考文献:Valentini,Piero; Rampa,Angela; Bisi,Alessandra,Medicinal Chemistry Research,1995,Vol. 5,# 4,P. 255-264
标题:Valentini,Piero; Rampa,Angela; Bisi,Alessandra,Medicinal Chemistry Research,1995,Vol. 5,# 4,P. 255-264

专利信息

专利号:WO-2011050245-A1
优先权日:2009-10-23
标 题:Bicyclic heteroaryls as kinase inhibitors
发明人：FENG YANGBO; CHEN YEN TING; SESSIONS HAMPTON; MISHRA JITENDRA K; CHOWDHURY SARWAT; YIN YAN; LOGRASSO PHILIP; LUO JUN-LI; BANNISTER THOMAS; SCHROETER THOMAS
权利人:FENG YANGBO; CHEN YEN TING; SESSIONS HAMPTON; MISHRA JITENDRA K; CHOWDHURY SARWAT; YIN YAN; LOGRASSO PHILIP; LUO JUN-LI; BANNISTER THOMAS; SCHROETER THOMAS
摘要:The invention is directed to heteroaryl compounds useful as inhibitors of various kinase enzymes. In various embodiments, the invention provides a heteroaryl compound having inhibitory bioactivity with respect to a Rho kinase, an AKT kinase, a p70S6K kinase, a LIM kinase, an IKK kinase, a Flt kinase, an Aurora kinase, or a Src kinase, or any combination thereof. Compounds of the invention include bicyclic heteroaryl compounds of formula (I), which can contain a bridging nitrogen atom at a ring junction. The invention further provides methods of synthesis of compounds of the invention, pharmaceutical compositions, pharmaceutical combinations, and methods of treatment of malconditions using compounds of the invention.

专利号:US-10766863-B2
优先权日:2014-11-17
标 题 :Monocarboxylate transport modulators and uses thereof
发明人：SANDANAYAKA VINCENT; WU QIONG
权利人:NIROGYONE THERAPEUTICS INC
摘要:The invention generally relates to the field of monocarboxylate transport modulators, e.g., monocarboxylate transport inhibitors, and more particularly to new substituted-quinolone compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in treating, modulating, forestalling and/or reducing physiological conditions associated with monocarboxylate transport activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, obesity, diabetes, cardiovascular diseases, tissue and organ transplant rejection, and malaria.

专利号:US-2008194590-A1
优先权日:2005-03-28
标 题:4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , X 2k , R 2l , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.