专利号:US-6712949-B2 优先权日:2001-07-22 标 题:Electrochemical synthesis of hydrogen peroxide 发明人:GOPAL RAMANATHAN 权利人:ELECTROSYNTHESIS CO INC 摘要:Improved methods and devices for the synthesis of hydrogen peroxide employing redox catalysts in a gas diffusion electrode or membrane electrode assembly in a semi-chemical/electrochemical system for the production of high purity, stable, usually acidic, aqueous solutions of peroxide at high conversion efficiencies without requiring organic solvents.
专利号:US-5962515-A 优先权日:1997-05-29 标题 :Process for isolation and synthesis of 1-(3,4 methylenedioxy-phenyl)-1E-tetradecene and its analogues and their activities against tumors and infections 发明人:UPADHYAY SHAKTI N; VISHWAKARMA RAM A; GHOSAL SABARI; SHUKLA SUPRIYA; BOSE CHANDA; KAMRA ANITA 权利人:NAT INST IMMUNOLOGY 摘要:Process for isolation of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene from Piper longum. Processes for synthesis of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene; its stereoisomers and analogues are disclosed. The compounds isolated and synthesized according to this invention have immunomodulatory properties and can be used to treat tumors and infections.
专利号:US-5112990-A 优先权日:1988-05-26 标 题 :Ruthenium-catalyzed production of cyclic sulfates 发明人:SHARPLESS K BARRY; GAO YUN 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones.
专利号:US-2009198084-A1 优先权日:2006-05-02 标题:Process for the deprotection of protected amines 发明人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES 权利人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES 摘要:The present invention relates to a process for the deprotection of protected amine compounds, wherein the protected amine compound is contacted with an electrophilic oxidating agent that is optionally formed in situ, said electrophilic oxidating agent being selected from the group of I 2 , Br 2 , Cl 2 and compounds comprising a halogen atom having a formal oxidation state of 1+, 3+, 5+ or 7+, provided that the electrophilic oxidating agent is not iodobenzene diacetate. The process can be conveniently employed in the synthesis of 1,3-amino alcohols, β-amino acids and heterocyclic compounds, in particular β-amino acids.
专利号:US-5248779-A 优先权日:1991-06-17 标 题 :Synthesis of nojirimycin derivatives 发明人:FLEET GEORGE W J 权利人:MONSANTO CO 摘要:Nojirimycin δ-lactam and deoxynojirimycin are each synthesized from 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-L-idofuranose as a divergent intermediate by a method which comprises formation of the piperidine ring by connection of nitrogen between C-1 and C-5 with inversion of configuration at C-5 to form nojirimycin δ-lactam or between C-2 and C-6 with inversion of configuration at C-2.
专利号:US-5200523-A 优先权日:1990-10-10 标 题 :Synthesis of nojirimycin derivatives 发明人:FLEET GEORGE W J 权利人:MONSANTO CO 摘要:Nojirimycin δ-lactam and deoxynojirimycin are each synthesized from 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-L-idofuranose as a divergent intermediate by a method which comprises formation of the piperidine ring by connection of nitrogen between C-1 and C-5 with inversion of configuration at C-5 to form nojirimycin δ-lactam or between C-2 and C-6 with inversion of configuration at C-2.
参考文献:10.1055/s-0031-1289638 摘要:Gooßen L, Rudzki M, Alcalde-Aragonés A, Dzik W, Rodríguez N. Selective Copper- or Silver-Catalyzed Decarboxylative Deuteration of Aromatic Carboxylic Acids. Synthesis. 2011 Dec 05;2012(02):184–93. doi: 10.1055/s-0031-1289638.