CAS: 33963-55-2; 2-(Methylsulfonyl)Benzoic Acid

该化合物是一种代苯酸衍生物,其分子式为C8H8O4S.该化合物的特点是,在苯甲酸环的2位置上存在甲烷硫磺酰胺组,这增强了其在有机合成中的回作用和效用.该化合物是制药和农用化学应用的多种中间体,特别是在合成磺酰胺化合物方面.甲烷硫酰胺组具有电镀特性,有利于核细胞替代反应.其晶体固体形式和极地有机溶剂中的中度溶性使其适合受控反应.该化合物因其稳定性和多步骤合成工艺的一贯性而受到重视.

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CAS号14092-00-3 2-甲苄基硫醇 | CAS号3724-10-5 2-甲硫基苯甲酸 | CAS号19093-34-6 2-(甲基亚磺酰)苯甲酸 | CAS号61670-15-3 benzo[b]thiophe... | CAS号623-11-0 对硝基甲苯 | CAS号49639-13-6 2-Methylsulfono... | CAS号412345-55-2 3-hydroxy-1,1-d... | CAS号89942-56-3 2-甲砜基苯腈 | CAS号5395-89-1 2-甲砜基苯甲醛 | CAS号3112-85-4 甲基苯基砜 | CAS号124-38-9 二氧化碳 | CAS号13736-79-3 1-甲氧基-2-(甲磺酰基)苯 | CAS号632339-04-9 1-(4-methylphen...

合成工艺路线路线简述

    📜3-Methoxy-Benzo[b]Thiophene-1,1-Dioxide置于sodium Hydroxide体系中,化学反应生成2-甲基磺酰苯甲酸
    参考文献:Arndt; Martius,Justus Liebigs Annalen Der Chemie,1932,Vol. 499,P. 228,283
    标题:Arndt; Martius,Justus Liebigs Annalen Der Chemie,1932,Vol. 499,P. 228,283

    海关参考信息

    专利信息


    专利号:US-6712949-B2
    优先权日:2001-07-22
    标 题:Electrochemical synthesis of hydrogen peroxide
    发明人:GOPAL RAMANATHAN
    权利人:ELECTROSYNTHESIS CO INC
    摘要:Improved methods and devices for the synthesis of hydrogen peroxide employing redox catalysts in a gas diffusion electrode or membrane electrode assembly in a semi-chemical/electrochemical system for the production of high purity, stable, usually acidic, aqueous solutions of peroxide at high conversion efficiencies without requiring organic solvents.

    专利号:US-5962515-A
    优先权日:1997-05-29
    标题 :Process for isolation and synthesis of 1-(3,4 methylenedioxy-phenyl)-1E-tetradecene and its analogues and their activities against tumors and infections
    发明人:UPADHYAY SHAKTI N; VISHWAKARMA RAM A; GHOSAL SABARI; SHUKLA SUPRIYA; BOSE CHANDA; KAMRA ANITA
    权利人:NAT INST IMMUNOLOGY
    摘要:Process for isolation of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene from Piper longum. Processes for synthesis of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene; its stereoisomers and analogues are disclosed. The compounds isolated and synthesized according to this invention have immunomodulatory properties and can be used to treat tumors and infections.

    专利号:US-5112990-A
    优先权日:1988-05-26
    标 题 :Ruthenium-catalyzed production of cyclic sulfates
    发明人:SHARPLESS K BARRY; GAO YUN
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones.

    专利号:US-2009198084-A1
    优先权日:2006-05-02
    标题:Process for the deprotection of protected amines
    发明人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
    权利人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
    摘要:The present invention relates to a process for the deprotection of protected amine compounds, wherein the protected amine compound is contacted with an electrophilic oxidating agent that is optionally formed in situ, said electrophilic oxidating agent being selected from the group of I 2 , Br 2 , Cl 2 and compounds comprising a halogen atom having a formal oxidation state of 1+, 3+, 5+ or 7+, provided that the electrophilic oxidating agent is not iodobenzene diacetate. The process can be conveniently employed in the synthesis of 1,3-amino alcohols, β-amino acids and heterocyclic compounds, in particular β-amino acids.

    专利号:US-5248779-A
    优先权日:1991-06-17
    标 题 :Synthesis of nojirimycin derivatives
    发明人:FLEET GEORGE W J
    权利人:MONSANTO CO
    摘要:Nojirimycin δ-lactam and deoxynojirimycin are each synthesized from 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-L-idofuranose as a divergent intermediate by a method which comprises formation of the piperidine ring by connection of nitrogen between C-1 and C-5 with inversion of configuration at C-5 to form nojirimycin δ-lactam or between C-2 and C-6 with inversion of configuration at C-2.

    专利号:US-5200523-A
    优先权日:1990-10-10
    标 题 :Synthesis of nojirimycin derivatives
    发明人:FLEET GEORGE W J
    权利人:MONSANTO CO
    摘要:Nojirimycin δ-lactam and deoxynojirimycin are each synthesized from 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-L-idofuranose as a divergent intermediate by a method which comprises formation of the piperidine ring by connection of nitrogen between C-1 and C-5 with inversion of configuration at C-5 to form nojirimycin δ-lactam or between C-2 and C-6 with inversion of configuration at C-2.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1055/s-0031-1289638
    摘要:Gooßen L, Rudzki M, Alcalde-Aragonés A, Dzik W, Rodríguez N. Selective Copper- or Silver-Catalyzed Decarboxylative Deuteration of Aromatic Carboxylic Acids. Synthesis. 2011 Dec 05;2012(02):184–93. doi: 10.1055/s-0031-1289638.
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