1H-十三氟己烷置于四溴化碳体系中,化学反应 24.0H,以38%的收率获得1-溴全氟乙烷 参考文献:Réactivité Par Voie Thermique De Rfh 标题:Réactivité Par Voie Thermique De Rfh 摘要:Hydroperfluoroalkanes Are Well Known As Being Rather Inert Chemically. Hydroperfluoroalkanes React At High Temperature With Carbon Tetrabromide And Carbon Tetrachloride To Yield Bromoperfluoroalkanes And Chloroperfluoroalkanes. Doi:10.1016/0022-1139(94)03137-O
专利号:US-5057633-A 优先权日:1989-11-24 标题 :Synthesis of perfluoroalkyl bromides 发明人:DRIVON GILLES; DURUAL PIERRE; GHENASSIA ELIE 权利人:ATOCHEM 摘要:The invention relates to the preparation of perfluoroalkyl bromides or bromoperfluoroalkanes C n F 2n+1 -Br (n=1 to 20). n A perfluoroalkanesulphonyl chloride C n F 2n+1 -SO 2 Cl is reacted with a compound of formula: ##STR1## in which X represents a nitrogen or phosphorus atom and R 1 , R 2 , R 3 and R 4 , which may be identical or different, each represent an optionally substituted hydrocarbon radical, it also being possible for one of these symbols to be a hydrogen atom.
专利号:US-2011104052-A1 优先权日:2007-12-03 标 题 :Methods of synthesis and use of chemospheres 发明人:BARNETT BRADLEY POWERS; GESCHWIND JEFFREY 权利人:UNIV JOHNS HOPKINS 摘要:The present invention provides, in general, compositions comprising a hydrogel and an agent, for example a therapeutic agent or an imaging agent, for locoregional delivery. In certain preferred embodiments of the invention, the hydrogel compositions are detectable by Magnetic Responance and CT Scan and are used for locoregional delivery of therapeutic agents, for example chemotherapeutic agents. The invention also features polymer matrix compositions comprising nanoparticles that can be loaded after polymerization with bioactive agents, for example a diagnostic agent or therapeutic agent.
专利号:JP-H03176435-A 优先权日:1989-11-24 标 题:Synthesis of perfluoroalkyl bromide
专利号:AU-635985-B2 优先权日:1989-11-24 标题:Synthesis of perfluoroalkyl bromides
专利号:EP-2229147-A2 优先权日:2007-12-03 标 题 :Methods of synthesis and use of chemospheres
专利号:WO-2009073193-A2 优先权日:2007-12-03 标题 :Methods of synthesis and use of chemospheres
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合成参考文献
摘要:Sawamura, M.; Ohmiya, H., Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis, (2019) 1, 105. 摘要:S25 | OECDPFAS | List of PFAS from the OECD | DOI:10.5281/zenodo.2648775 摘要:Luo, Y.-C.; Zhang, X., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 6. 摘要:Luo, Y.-C.; Zhang, X., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 15.