CAS: 2800-80-8; 3,3-Bis(3-Bromo-4-Hydroxyphenyl)-3H-Benzo[c][1,2]Oxathiole 1,1-Dioxide

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CAS号143-74-8 苯酚红 | CAS号81-08-3 2-磺基苯甲酸酐 | CAS号95-56-7 2-溴苯酚

酚红置于双氧水,Sodium Bromide体系中,用 Phosphate Buffer 用作溶剂,化学反应 5.83H,反应生成溴酚红,溴酚蓝
参考文献:Chemical Bromination Of Phenol Red By Hydrogen Peroxide Is Possible In The Absence Of Haloperoxidases
标题:Chemical Bromination Of Phenol Red By Hydrogen Peroxide Is Possible In The Absence Of Haloperoxidases
摘要:The Dye Phenol Red (Phenolsulphonphthalein) Was Chemically Brominated To Bromophenol Blue (3',3 ",5',5 "-Tetrabromophenolsulphonphthalein) Directly By Hydrogen Peroxide (20 Mm Or Higher) Under Acidic Ph (0.5-4.5) And Moderate Temperature (30 Degrees C). Since This Bromination Reaction Takes Place In The Absence Of Any Chemical Or Biological Catalyst,The Results Represent An Important Warning Concerning A Commonly Used Assay For Detecting Or Screening Haloperoxidases. Bromophenol Red (5',5 "-Dibromophenolsulphonphthalein) And Another Unidentified Compound Were Observed As Temporary Intermediates. Incubation Of The Reaction Mixture With Kcl Instead Of Nabr Did Not Yield Any Chlorinated Products Under The Same Conditions.. (C) 1998 Elsevier Science Ltd.
Doi:10.1016/s0045-6535(97)10032-7

专利信息

专利号:US-9976179-B2
优先权日:2011-03-30
标 题 :Nucleic acid sequencing technique using a pH-sensing agent
发明人：HAUSHALTER ROBERT C
权利人:PARALLEL SYNTHESIS TECH; PARALLEL SYNTHESIS TECH INC
摘要:The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.

专利号:US-4256727-A
优先权日:1978-09-18
标 题:Synthesis and use of diagnostic radio-pharmaceuticals comprising radioactive isotopes of bromine with dyes
发明人：TRIPLETT JOHN W; SMITH RANDALL B
权利人:UNIV KENTUCKY RES FOUND
摘要:A process for preparing bromine-containing dyes labelled with gamma-emitting isotopes of bromine, and the product thereof which is useful as an imaging agent for the hepato-biliary system, particularly in dynamic imaging methods. The dyes prepared are from the class of triarylmethane dyes, and also from the phthalein subclass of the class of xanthene dyes, and the labelling thereof is effected with 76Br, 77Br or 82Br. The process for preparing these dyes involves reacting the non-brominated dye precursor with either 76Br2, 77Br2 or 82Br2. This is a substitution type of reaction in which a ring hydrogen is substituted by either 76Br, 77Br or 82Br.

专利号:JP-H09503790-A
优先权日:1993-10-15
标题:Inhibition of extracellular matrix synthesis by antisense compounds directed to the nuclear oncogene.