专利号:US-5488167-A 优先权日:1993-10-18 标题 :Synthesis of sphingosines 发明人:HUDLICKY TOMAS 权利人:VIRGINIA TECH INTELL PROP 摘要:Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to obtain the desired sphingosine or derivative thereof.
专利号:US-2008214386-A1 优先权日:2004-03-01 标题:Catalyst for Cyclic Carbonate Synthesis 发明人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 权利人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 摘要:Provided are a solid catalyst which gives a cyclic carbonate at a high yield and a high selectivity, which is stable and which may be readily separated after reaction; and a method of industrially advantageous, inexpensive and safe production of a cyclic carbonate by the use of the catalyst. The catalyst contains an inorganic solid substance having a surface modified with an ionic substance containing a Group 15 element; or contains an ionic substance containing a Group 15 element, and an inorganic solid substance. The modifying group for surface modification of an inorganic solid substance is an ionic substance containing a Group 15 element. The ionic substance containing a Group 15 element is at least one substance selected from organic phosphonium salts, organic ammonium salts, organic arsonium salts and organic antimonium salts.
专利号:WO-9511222-A1 优先权日:1993-10-18 标题:Synthesis of sphingosines
专利号:JP-4224049-B2 优先权日:1993-10-18 标 题:Synthesis of sphingosine
专利号:JP-H09503786-A 优先权日:1993-10-18 标题:Synthesis of sphingosine
专利号:JP-3783730-B2 优先权日:1993-10-18 标 题 :Synthesis of sphingosine
参考标题:Asymmetric Synthesis Of Vicinal Amino Alcohols: Xestoaminol C, Sphinganine And Sphingosine 作者:Elin Abraham,Stephen G. Davies,Nicholas L. Millican,Rebecca L. Nicholson,Paul M. Roberts,Andrew D. Smith 摘要:Beta-Unsaturated Esters, Via Conjugate Addition Of Lithium (S)-N-Benzyl-N-(Alpha-Methylbenzyl)Amide And Subsequent In Situ Enolate Oxidation With (+)-(Camphorsulfonyl)Oxaziridine, Has Been Used As The Key Step In The Asymmetric Synthesis Of N,O-Diacetyl Xestoaminol C (41% Yield Over 8 Steps), N,O,O-Triacetyl Sphinganine (30% Yield Over 8 Steps) And N,O,O-Triacetyl Sphingosine (30% Yield Over 7 Steps)