CAS: 23627-87-4; 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One

上下游产品

uridine 5'-diphospho-D-galactose kaempferol UDP-glucoseD-Galactose kaempferol hepta-O-acetyltrifolin 4-hydroxy-benzoic acid

📜Kaempferol-3-O-(6-O-Galloyl-β-D-Galactopyranoside)置于sodium Carbonate体系中,用 甲醇,二甲基亚砜 用作溶剂,化学反应 3.33H,以22 Mg的收率获得三叶豆苷
参考文献:Isolation And Antioxidant Activity Of Galloyl Flavonol Glycosides From The Seashore Plant,Pemphis Acidula
标题:Isolation And Antioxidant Activity Of Galloyl Flavonol Glycosides From The Seashore Plant,Pemphis Acidula
摘要:在生长于亚热带海滨的一种植物--酸蚜的叶提取物中发现了四种没食子酰黄酮醇苷.通过光谱和化学分析,阐明了它们的化学结构为槲皮素或山奈酚 6''-O-没食子酰-β-D-苷.其中一种黄酮醇,即山奈酚-3-O-(6-O-烯丙基-β-D-吡喃半乳糖苷),是新近从天然来源中分离出来的,本次研究完全确定了其结构.通过 Dpph 抗自由基活性,抑制亚油酸甲酯氧化和抑制氧化性细胞死亡,考察了五倍子黄酮的抗氧化活性.这些结果与相应的非没食子酰化黄酮醇苷及其苷元的结果进行了比较.与相应的黄酮醇苷相比,五倍子酰基黄酮类化合物显示出更有效的活性,但在所应用的三种检测方法中,五倍子酰基黄酮类化合物的活性并不高于相应的苷元.
Doi:10.1271/bbb.65.1302

专利信息

专利号:US-2025257331-A1
优先权日:2024-02-09
标题 :FLAVONOID GLYCOSIDE GLYCOSYLTRANSFERASE LbUGT71BX1 IN LAPORTEA BULBIFERA AS WELL AS THE CODING GENE AND THE USE THEREOF
发明人：WU LAN; XIANG LI; GAO RANRAN; CHEN SHILIN; SHI YUHUA; YIN QINGGANG; WANG MENGYUE; CHU YANG; WANG WENTING
权利人:INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS
摘要:The invention discloses a flavonoid glycoside glycosyltransferase LbUGT71BX1 in laportea bulbifera as well as the coding gene and the use thereof. The amino acid sequence of the flavonoid glycoside glycosyltransferase LbUGT71BX1 is shown as SEQ ID NO: 2. The nucleotide sequence of the coding gene of the flavonoid glycoside glycosyltransferase LbUGT71BX1 is shown as SEQ ID NO: 1. According to the invention, on the basis of relevant results of the second-generation transcriptome and the third-generation full-length transcriptome sequencing of the laportea bulbifera , the last-step key enzyme LbUGT71BX1 for the synthesis of the flavonoid glycoside in the laportea bulbifera is screened and identified by using a reverse genetics method, filling the terminal blank of the biosynthesis pathway of the flavonoid glycoside in the laportea bulbifera.

专利号:EP-1493431-B1
优先权日:2003-07-03
标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
发明人：WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
权利人:MERCK PATENT GMBH
摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.