CAS: 1996-29-8; 1-Bromo-4-Chloro-2-Fluorobenzene

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CAS号57946-56-2 4-氯-2-氟苯胺 | CAS号160591-91-3 4-氯-2-氟苯硼酸 | CAS号117573-47-4 1,4-Epoxynaphth... | CAS号886615-30-1 3-溴-6-氯-2-氟苯甲醛

4-氯-2-氟苯胺置于氢溴酸,Sodium Nitrite,Copper(I) Bromide体系中,用 水 用作溶剂,化学反应 0.83H,反应生成1-溴-4-氯-2-氟苯
参考文献: 1-Aryl-4-Substituted Piperazines Derivatives For Use As Ccr1 Antagonists For The Treatment Of Inflammation And Immune Disorders[fr] Derives De Piperazines 1-Aryl-4-Susbtitues Utilises En Tant Qu'Antagonistes Du Ccr1 Dans Le Traitement De L'Inflammation Et Des Troubles Immunitaires
标题: 1-Aryl-4-Substituted Piperazines Derivatives For Use As Ccr1 Antagonists For The Treatment Of Inflammation And Immune Disorders[fr] Derives De Piperazines 1-Aryl-4-Susbtitues Utilises En Tant Qu'Antagonistes Du Ccr1 Dans Le Traitement De L'Inflammation Et Des Troubles Immunitaires
摘要:提供了作为ccr1受体强效拮抗剂的化合物,并且已经在动物炎症测试中进一步确认,炎症是ccr1的典型疾病状态之一.这些化合物通常是芳基哌嗪衍生物,在制药组合物,治疗ccr1介导疾病的方法以及用于鉴定竞争性ccr1拮抗剂的检测中具有用途.

专利信息

专利号:US-2010120784-A1
优先权日:2007-04-20
标题 :Novel heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LACHANCE NICOLAS; LI CHUN SING; LECLERC JEAN-PHILPPE; RAMTOHUL YEEMAN K
权利人:LACHANCE NICOLAS; LI CHUN SING; LECLERC JEAN-PHILPPE; RAMTOHUL YEEMAN K
摘要:Heteroaromatic compounds of structural formula (I) or a pharmaceutically acceptable salt thereof, wherein W is a substituted heteroaryl, X and Y are each independently a bond, —O—, —S—, —S(O)—, —S(O) 2 —, —NR 6 —, —C(O)—, —C(CH 3 )(OH)— or —C(CH 3 )â•?CH—, u (I) is an integer from 1 to 4, and Ar is an optionally substituted phenyl or naphtyl, are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD) The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis, obesity, Type 2 diabetes, insulin resistance, hyperglycemia, Metabolic Syndrome, neurological disease, cancer, and liver steatosis

专利号:CN-117466744-A
优先权日:2023-11-02
标 题:A method for photochemical iron-catalyzed synthesis of aromatic amine compounds