CAS: 1469-48-3; Cis-3A,4,7,7A-Tetrahydro-1H-Isoindole-1,3(2H)-Dione

相似化合物

85-40-5 130076-29-8 122131-81-1

上下游产品

CAS号21850-12-4 顺式-全氢异吲哚 | CAS号7506-66-3 顺式环己-1,2-二甲酰亚胺 | CAS号130076-29-8 2-BENZYL-3A,4,7... | CAS号1444-94-6 六氢邻苯二甲酰亚胺 | CAS号1470-99-1 顺式全氢异吲哚 | CAS号474925-37-6 顺式-3a,4,7,7a-四氢...

📜Cis-1,2,3,6-Tetrahydrophthalic Anhydride置于sodium Acetate,氯化铵体系中,用 溶剂黄146 用作溶剂,化学反应 72.0H,反应生成四氢酞酰亚胺
参考文献:的非还原对映体选择性开环ñ-二异丙与α,α,α',α'-四芳基-1,3-二氧戊环-4,5-Dimethanolate(甲基磺酰基)二甲
标题:的非还原对映体选择性开环ñ-二异丙与α,α,α',α'-四芳基-1,3-二氧戊环-4,5-Dimethanolate(甲基磺酰基)二甲
摘要:二环丙氧基钛taddolate将双环和三环内消旋-N-(甲基磺酰基)二甲酰亚胺1A-F对映体转化为异丙基[(磺酰胺基)羰基]-羧酸盐2A-F(产率为75-92%;参见方案3).产物的对映体比例在86:14至97:3之间,并且从ch 2 Cl 2 /己烷中重结晶得到对映体纯的磺酰胺基酯2(方案3).对映选择性与所用taddol的对映体过量显示线性关系(图3).还原酯基和羧酰胺基(lialh 4)和酰亚胺开环的产物2中磺酰胺基(red-Al)的额外还原裂解分别得到羟基磺酰胺3和氨基醇4(流程4).磺酰胺基酯2的绝对构型是通过化学相关性(与2A,B;方案6),对3E的樟脑酸酯的x射线分析(图1)以及对羟基苯甲酸酯的19 F-NMR分析确定的羟基磺酰胺3的较硬酯(表1).对于伯醇和胺的的绝对构型的分配的一般建议式hxch 2 Chr 1-[r 2,X = O,Nh,建议(见11在表1中).从2
Doi:10.1002/hlca.19960790328

专利信息

专利号:US-9944644-B2
优先权日:2013-03-14
标 题 :Octahydropyrrolopyrroles their preparation and use
发明人：PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI
权利人:PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI; UNIV COLUMBIA
摘要:The present invention provides compounds comprising variously substituted octahydropyrrolopyrroles, their synthesis, methods of making, methods of using, compositions and formulations thereof.

专利号:CN-111454196-A
优先权日:2020-05-12
标 题:A kind of production and synthesis method of cis-1,2,3,6-tetrahydrophthalimide

专利号:CN-115353481-A
优先权日:2022-08-31
标 题:A kind of catalytic synthesis method of cis-1,2,3,6-tetrahydrophthalimide

专利号:CN-115353481-B
优先权日:2022-08-31
标 题 :A catalytic synthesis method of cis-1,2,3,6-tetrahydrophthalimide

专利号:CN-108689910-B
优先权日:2018-05-18
标题 :Synthesis method of 1-cyclohexene-1, 2-dicarboximide