CAS: 1435-55-8; (S)-((1S,2R,4S,5R)-5-Ethylquinuclidin-2-yl)(6-Methoxyquinolin-4-yl)Methanol

相似化合物

522-66-7 522-66-7 5962-19-6

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CAS号56-54-2 奎尼丁 | CAS号612-11-3 3,4-二乙吡啶 | CAS号41037-26-7 6-甲氧基-4-甲基喹啉水合物 | CAS号86-68-0 6-甲氧基喹啉-4-甲酸 | CAS号113162-02-0 O-(4-氯苯甲酰)氢奎并啶 | CAS号140853-10-7 氢化奎宁 1,4-(2,3-二... | CAS号135042-89-6 氢化奎尼定 4-甲基-2-喹啉甲醚

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于sodium Ethanolate,氢化铝体系中,化学反应生成氢化奎尼定
参考文献:Rabe,Justus Liebigs Annalen Der Chemie,1932,Vol. 492,P. 242,255
标题:Rabe,Justus Liebigs Annalen Der Chemie,1932,Vol. 492,P. 242,255

专利信息

专利号:US-9126995-B2
优先权日:2011-11-08
标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
发明人：TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
权利人:NISSAN CHEMICAL IND LTD
摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-7173059-B2
优先权日:2003-05-08
标题:Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same
发明人：ALBIZATI KIM FRANCIS; BABU SRINIVASAN
权利人:AGOURON PHARMA
摘要:Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are disclosed.

专利号:US-6700001-B2
优先权日:2001-10-05
标 题:Process for stereoselective synthesis of 2-hydroxymethyl chromans
发明人：GROSS JONATHAN L; STACK GARY P
权利人:WYETH CORP
摘要:A process for the stereoselective synthesis of 2-hydroxymethyl-chromans of formula (II) is providedwhere R, R<1>, R<2 >and R<3 >are as defined herein. The compound of formula (II) is prepared using an optically active benzene compound of formula (I)where R<0 >is as defined herein. The 2-hydroxymethyl-chroman compounds of formula (II) are useful as intermediates for preparing a variety of medicinal agents.

专利号:US-5434152-A
优先权日:1993-11-08
标题:Asymmetric synthesis of (S)-(-)-6-chloro-4- cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone
发明人：HUFFMAN MARK A; YASUDA NOBUYOSHI; DECAMP ANN E; GRABOWSKI EDWARD J J
权利人:MERCK & CO INC
摘要:An asymmetric synthesis of (S)-(-)-6-chloro-4-cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone comprises the chiral addition of 2-pyridylacetylide to N 1 -protected 6-chloro-4-cyclopropyl-2-quinazolinone followed by removal of the protecting group.

专利号:US-9505733-B2
优先权日:2011-11-18
标题:Single step enantioselective process for the preparation of 3-substituted chiral phthalides
发明人：REDDY REKULA SANTOSH; NAGA CHITHANYA KIRAN INDUKURU; ARUMUGAM SUDALAI
权利人:COUNCIL SCIENT IND RES
摘要:The present invention discloses single step, highly enantioselective catalytic oxidative cyclization process for the synthesis of 3-substituted chiral phthalides. In particular, the invention discloses asymmetric synthesis of chiral phthalides via synergetic nitrile accelerated oxidative cyclization of o-cyano substituted aryl alkenes in high yield and enantiomeric excess (ee) in short reaction time. Also, disclosed herein is “one-potâ€? asymmetric synthesis of biologically important natural compounds having 3-substituted chiral phthalide structural framework in the molecule.