📜普拉克索置于氧气,孟加拉红内酯体系中,用 甲醇 用作溶剂,化学反应 2.0H,反应生成普拉克索杂质16
参考文献:Photo-Degradation Products Of Pramipexole
标题:Photo-Degradation Products Of Pramipexole
摘要:Two Pyrrolidine Compounds (1 And 2) Were Isolated From Photo-Degradation Of Bi-Sifrol Tablets. Compound 1 Was Esterified To P-Bromophenacyl Ester As Single-Crystal,And Then The Structure Was Elucidated By Single-Crystal X-Ray Study. Compound 2 Was Determined By 2D NMR And Mass Spectra. Otherwise,We Established That The Photo-Degradation Of Pramipexole Was Smoothly Carried Out In The Methanol Solution,And Elucidate The Degradation Mechanism. (C) 2012 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2012.02.044