CAS: 1020-31-1; 3,5-Di-Tert-Butylcatechol

该化合物是一种在化学应用中广泛用作有效聚合抑制剂和抗氧化剂的催化阻力,其主要优点包括高热稳定性和抗氧化降解性,使其特别适合稳定存储和加工过程中的聚苯乙烯,如苯乙烯,丙烯酸盐和其他乙烯化合物;三丁基乙基乙基乙醇组加强了其抑制性,提高了其清扫自由基的效率,防止过早聚合;该化合物还用于特殊化学合成和生产润滑剂和燃料抗氧化剂的中间体,其强劲的性能使它在严格的条件下成为工业用途的可靠选择.

结构式图片

相似化合物

98-29-3 5374-06-1 143767-20-8

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合成工艺路线路线简述

  • 90-05-1 = 1020-31-1 + 120-95-6 + 1620-98-0 + 4130-42-1 + 94-71-3 + 876-20-0 + 2934-05-6 + 5076-72-2 + 59056-76-7 + 52417-48-8 + 33963-27-8 + 87-97-8 + 79-74-3 + 2050-46-6 + 17540-75-9 + 2934-07-8 + 131358-04-8 + 21112-37-8 + 2078-54-8
    反应条件:1.1 Catalysts: Tungstic Acid (H2Wo4); Rt -> 300 °C; 6 H,300 °C
    标题:Highly Selective Conversion Of Guaiacol To Tert-Butylphenols In Supercritical Ethanol Over A H2Wo4 Catalyst
    作者:Mai,Fuhang; Et Al
    参考文献:Rsc Advances 日期:2019 卷标:9(5) 页码:2764-2771
3,6-Di-Tert-Butylbenzene-1,2-Diol置于硫酸体系中,用 苯 用作溶剂,化学反应 1.0H,反应生成3,5-二叔丁基邻苯二酚
参考文献:邻苯二酚-叔丁醇-硫酸-苯中邻苯二酚的烷基化
标题:邻苯二酚-叔丁醇-硫酸-苯中邻苯二酚的烷基化
摘要:邻苯二酚与烷基化叔丁基苯在硫酸的存在下醇,得到3,5-二-叔在比在具有类似的反应更高的收率丁苯-1,2-二醇叔丁基醇.通过降低释放的水的抑制作用,形成非均相系统以及在非极性有机相中发生烷基化过程,可以使该结果合理化.鉴定出中间产物,发现它们经历了分子内和分子间叔丁基的转移,形成了更稳定的3,5-二叔丁基苯-1,2-二醇.形成p-二-叔丁基苯表明苯参与了交叉烷基化过程.
Doi:10.1134/s1070428011090089

海关参考信息

专利信息


专利号:WO-2024189634-A1
优先权日:2023-03-13
标 题 :Highly atom economical process for synthesis of novel co-initiator for photo-induced radical polymerisation
发明人:KAPAT DR AJOY; AHMAD ASRAR; MITTAL GARVISHA
权利人:SHIV NADAR INSTITUTION OF EMINENCE DEEMED TO BE UNIV
摘要:The present invention relates to a base catalyzed sequential conjugate addition reaction for the synthesis of a novel and efficient co-initiator for Photo Induced Radical Polymerization. The process comprises synthesis of new co-initiator having 6,5 and 6,6-bicyclic scaffolds as central core. The process comprises reacting thiocarboxylic acid, catechol, thiocatechol, benzodithiol, benzothiocatechol and binol with ketone substrates at room temperature with a base and a solvent to yield the novel co-initiator compound of Formula 3, Formula 5, Formula C and Formula Z.

专利号:US-3663578-A
优先权日:1969-10-18
标题 :Catalytic oxidation of alkyl-substituted hydroquinones to the corresponding p-benzoquinones
发明人:KUTEPOW NIKOLAUS VON; MAGIN AUGUST; JOSCHEK HANS-INGO
权利人:BASF AG
摘要:AIR OXIDATION OF ALKYL-SUBSTITUTED HYDROQUINONES IN THE PRESENCE OF HEAVY METAL SALTS AS CATALYSTS IN A LIQUID MIXED PHASE CONSISTING OF AN AQUEOUS PHASE AND AN ORGANIC PHASE. THE AQUEOUS PHASE CONTAINS DISSOLVED CATALYST AND ADDITIVES FOR SETTING UP A PH BELOW 7, AND THE ORGANIC PHASE IS A SELECTIVE SOLVENT FOR THE ALKYL-SUBSTITUTED PBENZOQUINONE FORMED IN THE OXIDATION. THE PROCESS ENABLES 2,3,6-TRIMETHYLHYDROQUINONE, AN IMPORTANT INTERMEDIATE IN THE SYNTHESIS OF VITMIN E, TO BE SEPARATED FROM MIXTURES OF METHYL-SUBSTITUTED HYDROQUINONES.

专利号:WO-0078740-A1
优先权日:1999-06-23
标 题 :Solid-supported initiators and functional polymers for use in organic synthesis and combinatorial chemistry
发明人:HARIKRISHNAN LALGUDI SANKARAN; HODGES JOHN COOKE; LINDSLEY CRAIG WILLIAM
权利人:WARNER LAMBERT CO; HARIKRISHNAN LALGUDI SANKARAN; HODGES JOHN COOKE; LINDSLEY CRAIG WILLIAM
摘要:Solid-supported initiator and functional polymers are described as well as methods for the preparation and use in solution phase, solid-phase organic synthesis, and combinational chemistry including use as initiators of solid-supported free-radical polymerization, as solid-supported scavengers for purification of crude solution phase reaction mixtures, as a stationary phase for solid-phase organic synthesis, and as solid-supported reagents in solution-phase organic synthesis.

专利号:US-2007098676-A1
优先权日:2005-08-10
标 题 :Functionally diverse macromolecules and their synthesis
发明人:SIMANEK ERIC E; HOLLINK EMILY
权利人:SIMANEK ERIC E; HOLLINK EMILY
摘要:Functionally diverse macromolecules and synthetic routes for obtaining the same are disclosed. In certain embodiments, the synthesis proceeds in a divergent manner. In other embodiments, the routes rely on the differential reactivity of monomeric electrophilic triazine building blocks that display protected or unprotected groups. This diversity permits the facile introduction of a variety of diversity groups at multiple positions of these macromolecules, thereby setting the stage for further generational growth of the macromolecule and/or incorporation of other diversity groups such as biocompatible targeting groups.

专利号:US-10407676-B2
优先权日:2014-12-09
标题 :High efficiency, small volume nucleic acid synthesis
发明人:POEHMERER THOMAS; KUHN PHILLIP; NOTKA FRANK; ZEIDLER ANDREAS; HEIL KORBINIAN; TREFZER AXEL; FONNUM GEIR; KATZEN FEDERICO; ANDERSSON KRISTIAN
权利人:LIFE TECHNOLOGIES CORP; THERMO FISHER SCIENT GENEART GMBH; LIFE TECH AS
摘要:The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).

专利号:FR-3086659-A1
优先权日:2018-09-27
标题 :CATALYTIC PROCESS FOR SYNTHESIS OF MUCONIC ACID
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主要参考文献

[参考文献]: Caterina Lacava, Et Al. 3,5-Di-T-Butyl Catechol Is A Potent Human Ryanodine Receptor 1 Activator, Not Suitable For The Diagnosis Of Malignant Hyperthermia Susceptibility. Pharmacol Res. 2012 Jul;66(1):80-7.
[参考文献]: F Jensen, Et Al. Chemistry Of Singlet Oxygen--48. Isolation And Structure Of The Primary Product Of Photooxygenation Of 3,5-Di-T-Butyl Catechol. Photochem Photobiol. 1987 Sep;46(3):325-30.
[参考文献]: Fabio Fusi, Et Al. 3,5-Di-T-Butylcatechol (Dtcat) As An Activator Of Rat Skeletal Muscle Ryanodine Receptor Ca2+ Channel (Ryrc). Biochem Pharmacol. 2005 Feb 1;69(3):485-91.
[参考文献]: Jacky Chen, Et Al. Synthesis, Structure, Redox Properties And Azide Binding For A Series Of Biphenyl-Based Cu(Ii) Complexes. Dalton Trans. 2007 Jun 28:(24):2571-9.
[参考文献]: Kazi Sabnam Banu, Et Al. Catechol Oxidase Activity Of A Series Of New Dinuclear Copper(Ii) Complexes With 3,5-Dtbc And Tcc As Substrates: Syntheses, X-Ray Crystal Structures, Spectroscopic Characterization Of The Adducts And Kinetic Studies. Inorg Chem. 2008 Aug 18;47(16):7083-93.

合成参考文献


参考文献:10.1039/c0dt01598a
摘要:Sundaravel K, Suresh E, Saminathan K, Palaniandavar M. Iron(III) complexes of N2O and N3O donor ligands as functional models for catechol dioxygenase enzymes: ether oxygen coordination tunes the regioselectivity and reactivity. Dalton Trans. 2011 Aug 28;40(32):8092–107. doi: 10.1039/c0dt01598a.
参考文献:10.1021/ic200409d
摘要:Majumder S, Sarkar S, Sasmal S, Sañudo EC, Mohanta S. Heterobridged dinuclear, tetranuclear, dinuclear-based 1-d, and heptanuclear-based 1-D complexes of copper(II) derived from a dinucleating ligand: syntheses, structures, magnetochemistry, spectroscopy, and catecholase activity. Inorg Chem. 2011 Aug 15;50(16):7540–54. doi: 10.1021/ic200409d.
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