CAS: 55-52-7; Pheniprazine

该化合物是一种含有苯丙丙基主干体的氢氮衍生物,使其成为有机合成和制药应用的多用途中间体,其结构允许在形成氢氮酮,乙基循环和其他含氮化合物时有选择性的反应.该化合物因其苯丙基替代物而特别有助于合成生物活性分子,包括潜在的CNS目标剂.该化合物在控制功能化方面有优势,有利于对......

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C&L通报REACH预注册

合成工艺路线路线简述

    📜苯基丙酮 反应生成 苯异丙肼
    参考文献:Anderson,F.E. Et Al.,Journal Of Medicinal And Pharmaceutical Chemistry,1962,Vol. 5,# 2,P. 221-230
    标题:Anderson,F.E. Et Al.,Journal Of Medicinal And Pharmaceutical Chemistry,1962,Vol. 5,# 2,P. 221-230

    海关参考信息

    专利信息


    专利号:US-10925977-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
    发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
    权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
    摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

    专利号:US-8487134-B2
    优先权日:2008-10-09
    标 题:Process for the synthesis of amphetamine derivatives
    发明人:MEUDT ANDREAS; WISDOM RICHARD; HELMKE JASON; QIU QUOFANG; MEEK PAUL
    权利人:MEUDT ANDREAS; WISDOM RICHARD; HELMKE JASON; QIU QUOFANG; MEEK PAUL; ARCHIMICA INC
    摘要:The invention relates to processes for preparing acylated amphetamine, methamphetamine and dexamphetamine derivatives by reacting the parent amine with the to be-coupled acid or a salt of the to-be coupled acid which acid is optionally protected, in the presence of an alkylphosphonic acid anhydride as coupling agent and, if the acid was protected then cleaving the protecting group(s), in a one-pot reaction or in two or more separate steps.

    专利号:US-11377359-B2
    优先权日:2018-10-11
    标题:Process for producing liquid polysilanes and isomer enriched higher silanes
    发明人:NIKIFOROV GRIGORY; HUSSON GUILLAUME; ITOV GENNADIY; WANG YANG
    权利人:AIR LIQUIDE; AIR LIQUIDE AMERICAN
    摘要:Synthesis of silanes with more than three silicon atoms are disclosed (i.e., SinH(2n+2) with n=4-100). More particularly, the disclosed synthesis methods tune and optimize the isomer ratio by selection of process parameters such as temperature, residence time, and the relative amount of starting compounds, as well as selection of proper catalyst. The disclosed synthesis methods allow facile preparation of silanes containing more than three silicon atoms and particularly, the silanes containing preferably one major isomer. The pure isomers and isomer enriched mixtures are prepared by catalytic transformation of silane (SiH4), disilane (Si2H6), trisilane (Si3H8), and mixtures thereof.

    专利号:US-10814013-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Matveychuk D, Nunes E, Ullah N, Aldawsari FS, Velázquez-Martínez CA, Baker GB. Elevation of rat brain tyrosine levels by phenelzine is mediated by its active metabolite β-phenylethylidenehydrazine. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Aug 4;53:67-73. doi: 10.1016/j.pnpbp.2014.02.011. Epub 2014 Mar 6. Epub 2007 Apr 3. Review. Review. Polish. Japanese.

    合成参考文献


    参考文献:10.4103/0019-5545.82567
    摘要:Ramachandraih CT, Subramanyam N, Bar KJ, Baker G, Yeragani VK. Antidepressants: From MAOIs to SSRIs and more. Indian J Psychiatry. 2011 Apr;53(2):180–2.
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