CAS: 541-48-0; 3-Aminobutanoic Acid

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3775-73-3 3775-72-2 158851-30-0

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上下游产品

3-[Hydroxy-((S)-1-phenyl-ethyl)-amino]-butyric acid methyl ester

合成工艺路线路线简述

    📜3-Methyl-N-(S)-(1-Phenylethyl)Isoxazolidin-5-One置于palladium On Activated Charcoal 氢气体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 16.0H,以94%的收率获得产物dl-3-氨基-N-丁酸
    参考文献:合成异恶唑烷丁五酮的一般程序
    标题:合成异恶唑烷丁五酮的一般程序
    摘要:将n-取代的羟胺共轭添加到α,β-不饱和酯中,然后用双(三甲基甲硅烷基)氨基化锂将加合物环化,提供了合成异恶唑烷-5-酮的第一种通用方法,其n-苄基衍生物可以进行羟基化β-氨基酸.
    DOI:10.1016/s0040-4020(01)98811-8

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    专利信息


    专利号:US-6955915-B2
    优先权日:1989-06-07
    标题 :Apparatus comprising polymers
    发明人:FODOR STEPHEN P A; STRYER LUBERT; PIRRUNG MICHAEL C; READ J LEIGHTON; HOEPRICH PAUL D
    权利人:AFFYMETRIX INC
    摘要:A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protecting groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Cohen, Et Al. Local And Systemic Control Of Phytophthora Infestans In Tomato With Dl-3-Aminobutanoic Acid. Phytopathology. Volume: 84. Issue: 1. Pages: 55-9. Journal
    [参考文献]: J Gamir, Et Al. Identification Of Indole-3-Carboxylic Acid As Mediator Of Priming Against Plectosphaerella Cucumerina. Plant Physiol Biochem. 2012 Dec:61:169-79.
    [参考文献]: Jolanta Floryszak-Wieczorek, Et Al. Nitric Oxide-Mediated Stress Imprint In Potato As An Effect Of Exposure To A Priming Agent. Mol Plant Microbe Interact. 2012 Nov;25(11):1469-77.
    [参考文献]: Juhan Kim, Et Al. Cloning And Characterization Of A Novel Beta-Transaminase From Mesorhizobium Sp. Strain Luk: A New Biocatalyst For The Synthesis Of Enantiomerically Pure Beta-Amino Acids. Appl Environ Microbiol. 2007 Mar;73(6):1772-82.
    [参考文献]: Lennart Eschen-Lippold, Et Al. Dl-Beta-Aminobutyric Acid-Induced Resistance Of Potato Against Phytophthora Infestans Requires Salicylic Acid But Not Oxylipins. Mol Plant Microbe Interact. 2010 May;23(5):585-92.

    合成参考文献


    摘要:Hwang BY, Ko SH, Park HY, Seo JH, Lee BS, Kim BG. Identification of ω-aminotransferase from Caulobacter crescentus and site-directed mutagenesis to broaden substrate specificity. J Microbiol Biotechnol. 2008 Jan;18(1):48–54.
    参考文献:10.1128/jb.187.17.5910-5917.2005
    摘要:Geueke B, Namoto K, Seebach D, Kohler HP. A novel beta-peptidyl aminopeptidase (BapA) from strain 3-2W4 cleaves peptide bonds of synthetic beta-tri- and beta-dipeptides. J Bacteriol. 2005 Sep;187(17):5910–7.
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