CAS: 4569-86-2; 3-Amino-7-(Diethylamino)-5-Phenylphenazin-5-Ium Chloride

该化合物是属于三卤甲烷染料类的合成染料,其特征是其充满活力的紫色,这是其复杂的分子结构导致广泛共聚,导致可见频谱的强光吸收;这种染料在水中溶解,在各种条件下具有良好稳定性,适合各种应用,包括纺织品,生物污点和pH指标;甲基紫色3RAX具有与蛋白质和核酸结合的能力,在组织学和微生物研究中特别有用;然而,与许多合成染料一样,它可能对环境和健康造成危险,需要谨慎处理和处置;由于潜在的毒性,在某些地区对其使用进行管制,因此在与该化合物合作时必须遵守安全准则.

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2869-83-2 81-93-6 477-73-6

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上下游产品

aniline N,N-diethylaniline 41H40N9O2(1+)*C2F3O2(1-)C41H40N9O2(1+)*C2F3O2(1-) 39H41N11O7S*C2HF3O2C39H41N11O7S*C2HF3O2 31H32N9(1+)*C2F3O2(1-)C31H32N9(1+)*C2F3O2(1-)

合成工艺路线路线简述

    📜苯胺,N,N-二乙基对苯二胺置于盐酸,Potassium Dichromate体系中,用 Aq. Acetate Buffer 作为反应溶剂,化学反应 3.0H,以35%的收率获得产物氯化3-氨基-7-(二乙氨基)-5-苯基吩嗪翁
    参考文献:Methylene Violet 3Rax-Conjugated Porphyrin For Photodynamic Therapy: Synthesis,Dna Photocleavage,And Cell Study
    标题:Methylene Violet 3Rax-Conjugated Porphyrin For Photodynamic Therapy: Synthesis,Dna Photocleavage,And Cell Study
    摘要:一种具有出色生物医学特性的新型光动力疗法光敏剂可以简单地制备.
    DOI:10.1039/c7Ra13176C

    海关参考信息

    专利信息


    专利号:US-4118384-A
    优先权日:1976-02-21
    标题 :Process for preparation of azo dyestuffs by coupling in presence of aromatic sulphonic acid-formaldehyde reaction product
    发明人：MOLLS HANS-HEINZ; SCHIWY WILLY; HORNLE REINHOLD; NEBELING REINHARD
    权利人:BAYER AG
    摘要:Dyestuff dispersions and dyestuff solutions free from salt or at least having a low salt content are obtained in that the diazotization is carried out with addition of free dispersing agent acid to which, after the synthesis, either no basic agents are added or basic agents are added only up to a pH value of 3. The disclosed process gives dyestuff compositions of low salt content and results in readily dispersible dyestuffs when water insoluble dyestuffs are prepared and stable solutions when water soluble dyestuffs are prepared. The process is widely applicable and chemical constitution of the dyestuffs is conventional.

    专利号:EP-2333113-B1
    优先权日:2000-05-09
    标题:Covalent conjugates of nucleic acids with 1,4-bis-phenylazo-benzene and phenylazo-phenazine derivatives as dark quenchers of donor acceptor energy transfer for use e.g. in automated nucleic acid synthesis

    专利号:CN-112480098-A
    优先权日:2020-12-02
    标 题:A kind of methylene violet derivative fluorescent probe and its synthesis method and application

    专利号:CN-112480098-B
    优先权日:2020-12-02
    标题 :A kind of methylene violet derivative fluorescent probe and its synthesis method and application

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    主要参考文献

    [参考文献]: Onder S, Et Al. The Kinetics Of Inhibition Of Human Acetylcholinesterase And Butyrylcholinesterase By Methylene Violet 3Rax. Chem Biol Interact. 2019 Dec 1;314:108845.
    [参考文献]: Si Yao, Et Al. Methylene Violet 3Rax-Conjugated Porphyrin For Photodynamic Therapy: Synthesis, Dna Photocleavage, And Cell Study. Rsc Advances. 2022,12, 21004-21013.
    [参考文献]: S Brenner, Et Al. Supravital Staining Of Mitochondria With Phenosafranin Dyes. Biochim Biophys Acta. 1953 Aug;11(4):480-6.

    合成参考文献


    参考文献:10.1016/j.bbrc.2023.08.050
    摘要:Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and Biophysical Research Communications. 2023 Oct;679():116–21. doi: 10.1016/j.bbrc.2023.08.050.
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