CAS: 4175-77-3; 2,4-Dibromothiazole

上下游产品

CAS号2295-31-0 2,4-噻唑烷二酮 | CAS号2682-49-7 1,3-四氢噻唑-2-酮 | CAS号57314-13-3 2.4.5-三溴噻唑 | CAS号1062589-73-4 2-Bromo-5-(trib... | CAS号1078734-03-8 4-溴-2-(4-甲氧基苯基)噻唑 | CAS号34259-99-9 4-溴噻唑 | CAS号141305-40-0 4-溴-2-苯基噻唑 | CAS号376585-97-6 4-溴-2-(1-甲基乙基)噻唑 | CAS号208264-53-3 4-溴-2-乙酰基噻唑 | CAS号288-47-1 噻唑 | CAS号88982-82-5 4-溴-1,3-噻唑-2-羧酸 | CAS号761447-63-6 4-溴-2-(2-羟基-2-丙... | CAS号139669-96-8 2,4-二溴-5-噻唑羧酸

2,4-噻唑烷二酮置于四磷十氧化物,四丁基溴化铵体系中,化学反应生成 2,4-二溴噻唑
参考文献:吡咯并[2,3-D:5,4-D ']双噻唑:替代合成途径和对类似稠环联噻吩的比较研究
标题:吡咯并[2,3-D:5,4-D ']双噻唑:替代合成途径和对类似稠环联噻吩的比较研究
摘要:已开发出新的合成方法,用于从2,4-噻唑烷二酮制备4-烷基-和4-芳基-吡咯并[2,3-D:5,4-D ']双噻唑(pbtz)结构单元.所得的pbtz产品已通过结构,电子和光学方法进行了全面表征,因此可以与以前报道的双硫杂[3,2-B:2',3'-D]吡咯(dtp)类似物进行全面比较.然后,这种比较允许详细讨论用于调整父dtp构建块的属性的各种方法的相对电子效果.
DOI:10.1021/acs.Joc.7B02570

专利信息

专利号:US-6603015-B2
优先权日:1999-03-29
标题:Synthesis of epothilones
发明人：GEORG GUNDA I; NAIR SAJIV K; REIFF EMILY; TUNOORI ASHOK RAO
权利人:UNIV KANSAS
摘要:Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared using starting nitriles, which can alternately be oxidized to ketones and converted, or reacted to form the diol with subsequent conversion to the segment. Segment A precursors are prepared by reacting a starting enone with a chiral catalyst to give an intermediate alcohol in high enantomeric excess, followed by conversion of the alcohol to the desired Segment A precursor.

专利号:WO-2025010390-A1
优先权日:2023-07-05
标题 :Synthesis of pyruvate kinase activators
发明人：FANDRICK DANIEL; LEUNG CHUN YUEN; CRANE SHELDON; LACHANCE NICOLAS; LE ROUX ANTOINE; PATEL JIGNESH; VALAMALE ASHALATHA
权利人:AGIOS PHARMACEUTICALS INC
摘要:Provided herein are methods for preparing activators of Pyruvate Kinase (PK) or a salt or a hydrate thereof.

专利号:US-6457303-B1
优先权日:1999-03-29
标题:Synthesis of epothilones
发明人：GEORG GUNDA I; NAIR SAJIV K; REIFF EMILY; TUNOORI ASHOK RAO; HENRI JOHN T
权利人:UNIV KANSAS
摘要:Various epothilone precursors needed for the preparation of final epothilones are provided.

专利号:US-2002156289-A1
优先权日:1999-03-29
标 题 :Synthesis of epothilones

专利号:US-2002165415-A1
优先权日:1999-03-29
标 题:Synthesis of epothilones

专利号:US-6211412-B1
优先权日:1999-03-29
标题:Synthesis of epothilones