CAS: 292870-04-3; Benzyl 5-Amino-4-((Tert-Butoxycarbonyl)Amino)-5-Oxopentanoate
- 英文名称Benzyl 5-Amino-4-((Tert-Butoxycarbonyl)Amino)-5-Oxopentanoate
- 中文名称5-氨基-4-((叔丁氧基羰基)氨基)-5-氧代戊酸苄酯
- IUPAC名称benzyl 5-amino-4-((tert-butoxycarbonyl)amino)-5-oxopentanoate
- 其它别名Benzyl 5-Amino-4-[(Tert-Butoxycarbonyl)Amino]-5-Oxopentanoate; T-Boc-L-Isoglutamine-Alpha-Benzyl Ester; (S)-Benzyl 4-Amino-5-(Aminocarbonyl)Pentanoate, N4-Boc Protected; Benzyl L-Isoglutaminate, N-Boc Proteced; N4-Boc-(S)-Benzyl 4-Amino-5-(Aminocarbonyl)Pentanoate; (S)-N-(Benzyloxycarbonyl)Glutamic Amide Gamma-Benzyl Ester; Pentanoic Acid, 5-Amino-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-5-Oxo-, Phenylmethyl Ester; Benzyl 5-Amino-4-[(Tert-Butoxycarbonyl)Amino]-5-Oxopentanoate Usp/ep/bp
- CAS编号292870-04-3
- MFCD编号:MFCD01073597
- FDA UNII编号:C27S4SRN7U
- 分子式:C17H24N2O5分子量:336.39
- 产品CID: 1274890
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
55592-81-9 63091-89-4 18800-75-4物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2905122000-异丙醇
2905143000-叔丁醇
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专利信息
专利号:US-10927147-B2
优先权日:2015-12-10
标 题:Muramyl peptide derivative compound, synthesis and uses thereof
发明人：ELLA KRISHNA MURTHY; BRUNDA GANNERU; KUMAR HALMATHUR MAHABALARAO SAMPATH; SREEKANTH MIRYALA
权利人:BHARAT BIOTECH INT LTD; COUNCIL SCIENT IND RES
摘要:The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof. n n n n n n n n n n Wherein, R can be both linear and branched alkyl, aryl, substituted aryl and alkoxy alkyl. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.
专利号:US-10576147-B2
优先权日:2015-12-15
标题:Muramyl peptide derivative compound, synthesis and uses thereof
发明人：ELLA KRISHNA MURTHY; BRUNDA GANNERU; KUMAR HALMATHUR MAHABALARAO SAMPATH; SREEKANTH MIRYALA
权利人:BHARAT BIOTECH INT LTD; COUNCIL SCIENT IND RES
摘要:The invention relates to novel Muramyl Dipeptide (MDP) derivative compound of structural Formula-VIII, a process for synthesis, intermediates used in the synthesis and use thereof; n nwherein R 1 and R 2 both are hydrogen; or R 1 is hydrogen and R 2 is alkyl or aryl; or R 1 is alkyl or aryl and R 2 is hydrogen; or R 1 and R 2 both are alkyl or aryl (same or different groups); wherein alkyl group constitute C1-C6 alkyl or higher (both linear and branched) with or without heteroatoms; and aryl group constitute phenyl, substituted phenyl, heteraryl, arylalkyl and polynuclear aromatics. These compounds possess excellent pharmacological properties, in particular immunomodulating properties for use as adjuvant in vaccine formulations. These compounds are, particularly useful as adjuvants in vaccines.
