CAS: 28544-77-6; Pyridazine-3(2H)-Thione

相似化合物

53896-49-4 176658-62-1 5788-47-6

3-哒嗪酮置于tetraphosphorus Decasulfide体系中,用 吡啶 用作溶剂,化学反应 1.0H,以48%的收率获得哒嗪-3-硫醇
参考文献: Parp Inhibitors[fr] Inhibiteurs De Parp
标题: Parp Inhibitors[fr] Inhibiteurs De Parp
摘要:本申请披露了式i的化合物,其中变量r1和r2如本文所述,这些化合物是parp的抑制剂,并提供了含有式i化合物的化合物和组合物.本申请还提供了使用披露的parp抑制剂治疗parp介导的疾病和疾病的方法.

专利信息

专利号:US-3998816-A
优先权日:1973-04-16
标题 :7-[5-N-(n-Butoxyethoxy carbonyl and 2-chloroethoxy carbonyl)-amino] cephalosporins C
发明人：SEKI SHIGEO; ISHIMARU TOSHIYASU
权利人:MEIJI SEIKA KAISHA
摘要:New and useful cephem compounds derived from cephalosporin C are provided by this invention, which are valuable as intermediate for the synthesis of another bacteriocidally active cephem derivatives and which are readily extractable from its aqueous solution by means of an organic solvent and enable the cephalosporin C content in the aqueous fermentation broth filtrate to be recovered at an improved yield. Cephalosporin C present in the fermentation broth may be converted into the cephem compounds of this invention by reacting with a substituted chloroformate compound within said filtrate, and the cephem compounds so formed may then be extracted therefrom with an organic solvent. The cephem compounds of this invention further may be converted into a 7-acylamidocephalosporanic acid or 7-aminocephalosporanic acid through some successive reactions.