CAS: 2578-57-6; (S)-2-(Pyrrolidine-2-Carboxamido)Acetic Acid

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CAS号2766-18-9 Z-Pro-Gly-OH | CAS号7536-45-0 carbobenzyloxyp... | CAS号1148-11-4 N-CBZ-L-脯氨酸 | CAS号2766-31-6 Cbz-Pro-Gly-OEt | CAS号61350-60-5 Cbz-proline chloride | CAS号147-85-3 脯氨酸 | CAS号3705-27-9 环(甘氨酸-L-脯氨酸)二肽 | CAS号490-01-7 N-(1-trifluoroa... | CAS号33256-35-8 H-Pro-Gly-OMe | CAS号2966-05-4 N-trifluoroacet... | CAS号3705-27-9 环(甘氨酸-L-脯氨酸)二肽 | CAS号675-20-7 2-氮己环酮 | CAS号2766-18-9 Z-Pro-Gly-OH | CAS号2441-63-6 H-Gly-Pro-Gly-OH | CAS号72122-62-4 β-酪啡肽,牛

甲基1-{[(2-甲基-2-丙基)氧基]羰基}-L-脯氨酰甘氨酸酯置于三氟乙酸,Sodium Hydroxide体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 7.0H,反应生成(吡咯烷-2-羰基)-氨基-乙酸
参考文献:Aggregation Propensity Of Amyloidogenic And Elastomeric Dipeptides Constituents
标题:Aggregation Propensity Of Amyloidogenic And Elastomeric Dipeptides Constituents
摘要:This Study Demonstrates The Self-Assembly Of N-And C-Terminal Protected Dipeptides Phe-Gly And Pro-Gly Which Were Derived From Amyloidogenic And Elastomeric Peptide Sequences. These Constituents Afforded Nanostructured Supramolecular Ensembles Through Various Non-Covalent Interactions In The Solid State Which Can Be Directly Correlated With Their Fibrillation Event In Solution Phase. Interestingly Microscopic Observations Revealed That The Amyloidogenic Dipeptide Constituents Assembled Into Hollow Tubular Structures Whereas The Elastomeric Dipeptide Constituents Assembled Into The Feather Or Sheet Like Structures. (C) 2016 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tet.2016.07.022

专利信息

专利号:US-4242256-A
优先权日:1977-03-15
标 题 :Synthesis of peptide analogues
发明人：SHARPE ROBERT; SZELKE MICHAEL
权利人:SHARPE ROBERT; SZELKE MICHAEL
摘要:Compounds being analogues of a dipeptide in which the nitrogen atom of the linking amide group of the dipeptide is replaced by trivalent group ##STR1## and in which, optionally, the carbonyl function of this linking group is replaced by the divalent group --CH 2 -- are of value in the synthesis of isosterically modified peptides.

专利号:US-9556108-B2
优先权日:2014-07-10
标题 :Process for preparing substituted phenylalkanes
发明人：LIAO SUBO; MCCLURG JOSEPH; TRAWICK BOBBY
权利人:MALLINCKRODT LLC
摘要:The invention provides methods for preparing substituted phenylalkanes. In particular, the processes comprise reacting a phenyl boronic compound with an α-β unsaturated carbonyl-containing compound via an asymmetric 1,4-addition reaction. The processes may be useful in the synthesis of tapentadol.

专利号:CN-113912524-B
优先权日:2021-10-25
标题:A kind of sulfur amide-containing polypeptide compound and its synthesis method