CAS: 2388-73-0; 2-Methoxythioanisole

上下游产品

CAS号529-28-2 邻碘苯甲醚 | CAS号67-68-5 二甲基亚砜 | CAS号1073-29-6 2-羟基茴香硫醚 | CAS号74-88-4 碘甲烷 | CAS号17733-22-1 2-氯茴香硫醚 | CAS号124-41-4 甲醇钠 | CAS号38452-13-0 1-methoxy-2-met... | CAS号624-92-0 二甲基二硫醚 | CAS号100-66-3 苯甲醚 | CAS号7217-59-6 邻甲氧基苯硫酚 | CAS号18619-21-1 (2-Methoxy-phen... | CAS号27489-33-4 2-(甲基磺酰)苯酚 | CAS号7217-59-6 邻甲氧基苯硫酚 | CAS号1073-29-6 2-羟基茴香硫醚 | CAS号578-58-5 邻甲基苯甲醚 | CAS号100-66-3 苯甲醚 | CAS号1121-24-0 2-羟基苯硫酚 | CAS号13736-79-3 1-甲氧基-2-(甲磺酰基)苯 | CAS号84413-73-0 1-methoxy-2-[(S... | CAS号84413-74-1 (R)-1-methoxy-2...

1-Methylsulfinyl-2-Methoxybenzene置于[ir(Df(Cf3)Ppy)2(Dtbbpy)](Pf6),三苯基膦体系中,用 二氯甲烷 用作溶剂,化学反应 24.0H,以25%的收率获得2-甲氧基茴香硫醚
参考文献:使用可见光对亚砜进行光催化脱氧:机理研究和合成应用.
标题:使用可见光对亚砜进行光催化脱氧:机理研究和合成应用.
摘要:报道了通过ir [(df(cf 3)ppy)2(dtbbpy)] Pf 6或fac-Ir(ppy)3促进的亚砜的光催化脱氧生成硫化物.机理研究表明,自由基链机理起作用,其通过由自由基/极性交叉过程产生的磷酰基自由基进行.发现自由基链的引发通过两种相反的光催化猝灭机理进行,从而提供互补的反应性.自由基脱氧过程的温和性质使得能够以通常的高分离收率还原多种官能化的亚砜,包括那些含有酸敏感基团的亚砜.
Doi:10.1021/acscatal.0C00690

专利信息

专利号:US-8367871-B2
优先权日:2007-03-09
标 题 :Process for production of optically active sulfoxide compound using iron-salan complex catalyst
发明人：KATSUKI TSUTOMU; EGAMI HIROMICHI
权利人:NISSAN CHEMICAL IND LTD; KATSUKI TSUTOMU; EGAMI HIROMICHI
摘要:An optically active sulfoxide compound that is useful as an intermediate for synthesis or an active ingredient of a physiologically active substance such as a pharmaceutical agent is produced at a high optical purity. A process for producing an optically active sulfoxide compound of formula (4) comprises oxidizing a sulfide compound of formula (3) in the presence of an optically active metal complex of formula (1), (1′), (2) or (2′) by using an oxidizing agent. The present invention is also directed to the optically active metal complex.

专利号:US-8754237-B2
优先权日:2006-02-14
标题:Bifunctional histone deacetylase inhibitors
发明人：BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L
权利人:BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.

专利号:US-8304451-B2
优先权日:2006-05-03
标题 :Histone deacetylase and tubulin deacetylase inhibitors
发明人：MAZITSCHEK RALPH; KWIATKOWSKI NICHOLAS PAUL; BRADNER JAMES ELLIOT
权利人:MAZITSCHEK RALPH; KWIATKOWSKI NICHOLAS PAUL; BRADNER JAMES ELLIOT; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel inhibitors of histone deacetylases, tubulin deacetylases, and/or aggresome inhibitors, and pharmaceutically acceptable salts and derivatives thereof. The inventive compounds fall into two classes—“isotubacinâ€? class and “isoisotubacinâ€? class—all of which include a 1,3-dioxane core. The present invention further provides methods for treating disorders regulated by histone deacetylase activity, tubulin deacetylase activity, and/or the aggresome (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, protein degradation disorders, protein deposition disorders, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.

专利号:US-8178579-B2
优先权日:2001-05-09
标 题:Dioxanes and uses thereof
发明人：SCHREIBER STUART L; STERNSON SCOTT M; WONG JASON C; GROZINGER CHRISTINA M; HAGGARTY STEPHEN J; KOELLER KATHRYN M
权利人:SCHREIBER STUART L; STERNSON SCOTT M; WONG JASON C; GROZINGER CHRISTINA M; HAGGARTY STEPHEN J; KOELLER KATHRYN M; HARVARD COLLEGE
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I): n nand pharmaceutically acceptable derivatives thereof, wherein R 1 , R 2 , R 3 , n, X and Y are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. The present invention further provides compounds capable of inhibiting histone deacetylatase activity and methods for treating disorders regulated by histone deacetylase activity (e.g., cancer and protozoal infections) comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof. The present invention additionally provides methods for modulating the glucose-sensitive subset of genes downstream of Ure2p. The present invention also provides methods for preparing compounds of the invention.