合成目标产物 6-Benzylaminopurine 主要起始原料 6-Chloropurine And Benzylamine
(文献来源)合成步骤主要原料 6-Chloropurine 和 Benzylamine
7-Benzyl-6-Benzylamino-2-Chloropurine置于palladium On Activated Charcoal 氢氧化钾,氢气体系中,用 乙醇 用作溶剂,化学反应 15.0H,以69%的收率获得6-苄氨基嘌呤 参考文献:Synthesis Of N6-Substituted Adenines From 3-Methylxanthine 标题:Synthesis Of N6-Substituted Adenines From 3-Methylxanthine 摘要: Doi:10.1007/bf02269545
专利号:US-2003159164-A1 优先权日:1998-05-29 标 题:Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products 发明人:KOPCHICK JOHN JOSEPH; KELDER BRUCE; HUANG YUNG-SHENG; KIRCHNER STEPHEN J; MUKERJI PRADIP 摘要:The invention generally relates to synthesis of essential fatty acids and their derivatives, long-chain polyunsaturated fatty acids (LC-PUFAs) and eicosanoids in transfected cells and in transgenic animals.
专利号:US-5344775-A 优先权日:1991-11-15 标题 :Synthesis of taxanes in culture using pseudocalluscells 发明人:SMITH RICHARD J 权利人:ESCAGENETICS CORP 摘要:A method of synthesis of taxanes from pseudocallus of Taxus species, particularly T. baccata , and methods for pseudocallus production are described. Pseudocallus of the invention can be distinguished from callus tissue and cell suspensions by (1) its unique morphology which is characterized by an amorphous aggregation of cells lacking both differentiated tissues and clearly defined meristematic zones; by (2) very poor intercellular adhesion resulting in marked tissue friability; and by (3) relatively high initial rate of mass doubling. Production of taxanes is achieved by culturing the pseudocallus on support culture medium.
专利号:US-4849513-A 优先权日:1983-12-20 标 题 :Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups 发明人:SMITH LLOYD M; FUNG STEVEN; KAISER ROBERT J 权利人:CALIFORNIA INST OF TECHN 摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.
专利号:US-5118802-A 优先权日:1983-12-20 标 题:DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside 发明人:SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J 权利人:CALIFORNIA INST OF TECHN 摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.
专利号:US-7429657-B2 优先权日:1994-11-10 标 题 :DNA molecules encoding enzymes involved in starch synthesis, vectors, bacteria, transgenic plant cells and plants containing these molecules 发明人:KOSSMANN JENS; SPRINGER FRANZISKA; ABEL GERNOT J 权利人:BAYER CROPSCIENCE AG 摘要:The present invention relates to DNA molecules encoding enzymes which are involved in the starch synthesis of plants. These enzymes represent two different isotypes of the soluble starch synthase as well as a starch granule-bound starch synthase. This invention furthermore relates to vectors, bacteria, as well as to plant cells transformed with the DNA molecules described and to plants regenerated from them. n Furthermore, the invention relates to starch that can be isolated from plants having an increased or reduced activity of the proteins described.
专利号:US-7541172-B2 优先权日:1998-08-27 标题:Transgenic amorpha-4, 11-diene synthesis 发明人:WALLAART THORVALD EELCO; BOUWMEESTER HENDRIK JAN 权利人:INST ONEWORLD HEALTH 摘要:The present invention relates to an isolated DNA sequence encoding a polypeptide having the biological activity of amorpha-4,11-diene synthase. This DNA sequence can be used for the transformation of bacteria, yeasts and plants for the production of amorpha-4,11-diene, a specific precursor in the synthesis of artemisinin, in the respective organisms. The invention also relates to these organisms.
1: Křikavová R, Hošek J, Suchý P Jr, Vančo J, Trávníček Z. Diverse in vitro and in vivo anti-inflammatory effects of trichlorido-gold(III) complexes with N6-benzyladenine derivatives. J Inorg Biochem. 2014 May;134:92-9. doi: 10.1016/j.jinorgbio.2014.02.002. Epub 2014 Feb 14.
合成参考文献
参考文献:10.1007/s00299-005-0074-5 摘要:Li Y, Sun M, Liu J, Yang Z, Zhang Z, Shen G. High expression of foot-and-mouth disease virus structural protein VP1 in tobacco chloroplasts. Plant Cell Rep. 2006 Apr;25(4):329–33. doi: 10.1007/s00299-005-0074-5. 参考文献:10.1007/s10265-011-0442-x 摘要:Wang XL, Liu D, Li ZQ. Effects of the coordination mechanism between roots and leaves induced by root-breaking and exogenous cytokinin spraying on the grazing tolerance of ryegrass. J Plant Res. 2012 May;125(3):407–16. doi: 10.1007/s10265-011-0442-x. 参考文献:10.1007/s00122-011-1651-3 摘要:Ma H, Kong Z, Fu B, Li N, Zhang L, Jia H, Ma Z. Identification and mapping of a new powdery mildew resistance gene on chromosome 6D of common wheat. Theor Appl Genet. 2011 Nov;123(7):1099–106. doi: 10.1007/s00122-011-1651-3. 参考文献:10.1094/mpmi-05-11-0142 摘要:Heckmann AB, Sandal N, Bek AS, Madsen LH, Jurkiewicz A, Nielsen MW, Tirichine L, Stougaard J. Cytokinin induction of root nodule primordia in Lotus japonicus is regulated by a mechanism operating in the root cortex. Mol Plant Microbe Interact. 2011 Nov;24(11):1385–95. doi: 10.1094/mpmi-05-11-0142. 参考文献:10.1007/s00709-011-0304-3 摘要:Seung D, Risopatron JP, Jones BJ, Marc J. Circadian clock-dependent gating in ABA signalling networks. Protoplasma. 2012 Jul;249(3):445–57. doi: 10.1007/s00709-011-0304-3.