CAS: 1193-62-0; Methyl 1H-Pyrrole-2-Carboxylate

上下游产品

吡咯-2-羧酸 Pyrrole-2-Carboxyl Acid 634-97-9

L-脯氨酸甲酯盐酸盐置于β-环糊精,2-碘酰基苯甲酸体系中,用 水 用作溶剂,化学反应 4.0H,以89%的收率获得2-吡咯甲酸甲酯
参考文献:O-Iodoxybenzoic Acid (Ibx): A Versatile Reagent For The Synthesis Of N-Substituted Pyrroles Mediated By β-Cyclodextrin In Water
标题:O-Iodoxybenzoic Acid (Ibx): A Versatile Reagent For The Synthesis Of N-Substituted Pyrroles Mediated By β-Cyclodextrin In Water
摘要:O-Iodoxybenzoic Acid (Ibx),A Very Mild And Efficient Hypervalent Iodine(V) Reagent,Aromatizes Diversely Substituted 1-Benzylpyrrolidines And N-Substituted L-Proline Analogues To The Corresponding Substituted Pyrroles In Good To Excellent Yields Under Mild Conditions Mediated By Beta-Cyclodextrin In Water At Room Temperature. To The Best Of Our Knowledge,This Is The First Report On Ibx,Promoting Complete Aromatization Leading To N-Benzylpyrroles From The Corresponding Saturated Five Membered Heterocyclic Derivatives In Water Medium. (C) 2011 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2011.06.077

专利信息

专利号:US-10919904-B2
优先权日:2016-08-17
标 题 :Northern-southern route to synthesis of bacteriochlorins
发明人：LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU
权利人:UNIV NORTH CAROLINA STATE
摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).

专利号:US-2019256521-A1
优先权日:2016-08-17
标题:Northern-southern route to synthesis of bacteriochlorins

专利号:WO-2018035281-A1
优先权日:2016-08-17
标 题:Northern-southern route to synthesis of bacteriochlorins

专利号:US-6514997-B2
优先权日:1999-12-03
标题:Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
发明人：DRAGOVICH PETER S; PRINS THOMAS J; ZHOU RU; JOHNNSON JR THEODORE O
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the picornaviral 3C protease. Also disclosed are compounds of the formula: n where the formula variables are as defined herein that advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as rhinovirus 3C proteases. Intermediates and synthetic methods for preparing such compounds are also described.

专利号:US-4075225-A
优先权日:1976-06-29
标 题:Pyrrolo[2,1-b][3]benzazepines
发明人：ROKACH JOSHUA; ATKINSON JOSEPH G; ROONEY CLARENCE S
权利人:MERCK & CO INC
摘要:6,11-Dihydro-5H-Pyrrolo[2,1-b][3]benzazepin-11-one and derivatives thereof are generally prepared by Friedel-Crafts ring closure of a N-phenethylpyrrole-2-carboxylic acid halide. They are useful intermediates in the synthesis of skeletal muscle relaxants and tranquilizers such as 11-(3-dimethylaminopropylidene)-6,11-dihydro-5H-pyrrolo[2,1-b][3]benza zepine.

专利号:US-4056536-A
优先权日:1976-06-29
标 题:Pyrrolo[2,1-b][3]benzazepines
发明人：ATKINSON JOSEPH G; BELANGER PATRICE C; ROONEY CLARENCE S; BRITCHER SUSAN F
权利人:MERCK & CO INC
摘要:11H-Pyrrolo[2,1-b][3]benzazepin-11-one and derivatives thereof are generally prepared by Friedel-Crafts ring closure of a N-styrylpyrrole-2-carboxylic acid derivative. They are useful intermediates in the synthesis of skeletal muscle relaxants and tranquilizers such as 11-(3-dimethylaminopropylidene)-2-cyano-11H-pyrrolo[2,1-b][3]benzazepi ne.