CAS: 112-63-0; (9Z,12Z)-Methyl Octadeca-9,12-Dienoate

相似化合物

2541-61-9 506-21-8 60-33-3

上下游产品

CAS号67-56-1 甲醇 | CAS号544-35-4 亚油酸乙酯 | CAS号60-33-3 亚油酸 | CAS号1360168-38-2 1-D-arabinitol ... | CAS号124-41-4 甲醇钠 | CAS号64833-94-9 linoleic acid i... | CAS号62439-44-5 methyl °Ctadeca... | CAS号1190-63-2 十八烷酸十六烷基酯 | CAS号17673-53-9 °Ctadecyl (9Z,1... | CAS号33001-45-5 1,2-异亚丙基-3-油酰基-sn-甘油 | CAS号127592-95-4 1-油烯基-2,3-异亚丙基-... | CAS号18418-21-8 Hexadecanoic ac... | CAS号544-35-4 亚油酸乙酯 | CAS号506-43-4 亚麻醇 | CAS号14606-78-1 methyl 10-hydro... | CAS号553-90-2 草酸二甲酯 | CAS号627-93-0 己二酸二甲酯 | CAS号1732-10-1 壬二酸二甲酯 | CAS号1119-40-0 戊二酸二甲酯

📜甲基十八碳-9,12-二炔酸酯置于乙醇,钯,苯体系中,化学反应生成亚油酸甲酯
参考文献:Sarytschewa Et Al.,Zhurnal Obshchei Khimii,1959,Vol. 29,P. 2318,2321; Engl. Ausg. S. 2283,2285
标题:Sarytschewa Et Al.,Zhurnal Obshchei Khimii,1959,Vol. 29,P. 2318,2321; Engl. Ausg. S. 2283,2285

专利信息

专利号:US-2024294462-A1
优先权日:2023-02-15
标题:Method for the Synthesis of Ionizable Lipids Using a Doubly Alkylated Intermediate
发明人：SAADATI FARIBA; TRAN HUY; CIUFOLINI MARCO; ATMURI N D PRASAD
权利人:NANOVATION THERAPEUTICS INC
摘要:Provided herein is a method for the preparation of ionizable, cationic amino lipids using a doubly alkylated nucleophilic intermediate to produce a ketone. The ketone, or a corresponding alcohol, is subjected to one or more synthesis steps to add an ionizable moiety thereto. The method can be advantageously employed for the synthesis of unsymmetrical analogues of the above lipids that would be considerably more difficult to make by alternative strategies. The method can also be used to prepare symmetrical ionizable, cationic amino lipids with fewer steps and/or with the use of fewer hazardous chemicals than known synthesis methods.

专利号:US-5872245-A
优先权日:1992-09-30
标题 :Continuous process for the synthesis of sucrose fatty acid esters
发明人：WILSON DONALD C
权利人:OPTIMA TECHNOLOGIES GROUP
摘要:This present invention pertains to a process for the synthesis of sucrose fatty acid esters by reacting sucrose and a purified specific fatty acid ester under substantially solvent free conditions in the presence of a transesterification stationary catalyst and mechanical emulsification. The process is continuous, yielding selected individual products of separated simple sucrose fatty acid esters of mono-, di-, tri- and polyesters while recycling the unwanted ester fractions, the unreacted sucrose and fatty acid ester.

专利号:US-2005233427-A1
优先权日:2004-03-31
标题 :Processes for the production of triglycerides of unsaturated fatty acids in the presence of enzymes
发明人：SCHOERKEN ULRICH; MEYER CAROLIN; BOTH SABINE; HORLACHER PETER
权利人:SCHOERKEN ULRICH; MEYER CAROLIN; BOTH SABINE; HORLACHER PETER
摘要:Processes for the enzyme-catalyzed synthesis of triglycerides containing polyunsaturated fatty acids in which the synthesis is preceded by a pre-hydrolysis in which (a) C 1-4 alkyl esters of polyunsaturated fatty acids are completely or partly hydrolyzed in vacuo with continuous addition of water or are partly hydrolyzed in several stages without vacuum, (b) after the hydrolysis, the water is removed by separation or distillation and (c) the synthesis of the polyunsaturated fatty acids with glycerol in vacuo in the presence of an enzyme to form their triglycerides is carried out under low-water conditions, (d) the enzymes are removed from the triglyceride by separation or filtration and (e) the remaining fatty acids and/or possible residues of C 1-4 alkyl esters are removed from the triglyceride by distillation or refining; the pre-hydrolysis and the subsequent synthesis preferably being carried out as a one-pot process in the same reactor and in the presence of the same enzyme.

专利号:US-6342619-B2
优先权日:1999-04-01
标题:Synthesis of conjugated fatty acid
发明人：SEIDEL MICHAEL C
摘要:A synthesis process is disclosed for producing a conjugated fatty acid at specified temperature in high yield, including providing an ester of a fatty acid having somewhere in its carbon chain a chain of four carbon atoms such that carbon one bears one hydrogen and one hydroxyl group, carbon two bears two hydrogen atoms, and a double bond is positioned between carbon three and carbon four and reacting with a chloride selected from the group consisting of toluenesulfonyl chloride, methanesulfonyl chloride, benzenesulfonyl chloride, alkylsulfonyl chloride, and arylsulfonyl chloride at a temperature in the range of 10° C.-100° C., preferably 20° C.-50° C. The synthesis process provides a conjugated fatty acid formed from the ester reacted with diazabicycloundecene. In one aspect, the ester is formed in a pyridine solvent. In one aspect, a mesylate is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the reaction with diazabicyclo-undecene is conducted in a polar, non-hydroxylic solvent of acetonitrile to form a preferred isomer at the specified temperature in high yield.

专利号:US-6160141-A
优先权日:1997-02-18
标 题 :Synthesis of conjugated eicosadienoic acid
发明人：SEIDEL MICHAEL C
摘要:A synthesis process for producing 11-cis, 13-trans eicosadienoic acid at room temperature in high yield is disclosed, including providing a tosylate or mesylate of a methyl lesquerolate and 11-cis, 13-trans eicosadienoic acid formed when the tosylate or mesylate reacts with diazabicyclo-undecene. In one aspect, the tosylate of the methyl lesquerolate is formed with tosyl chloride in a pyridine solvent. In one aspect, the mesylate of the methyl lesquerolate is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the tosylate or mesylate is reacted with diazabicyclo-undecene in a polar, non-hydroxylic solvent of acetonitrile to form the preferred isomer of 11-cis, 13-trans eicosadienoic acid at room temperature in high yield.

专利号:US-5892074-A
优先权日:1997-02-18
标 题:Synthesis of conjugated linoleic acid (CLA)
发明人：SEIDEL MICHAEL C
摘要:A synthesis process for producing 9-cis, 11-trans octadecadienoic acid at room temperature in high yield is disclosed, including providing a tosylate or mesylate of a methyl ester of ricinoleic acid and 9-cis, 11-trans octadecadienoic acid formed when the tosylate or mesylate reacts with diazabicyclo-undecene. In one aspect, the tosylate of the methyl ester of ricinoleic acid is formed with tosyl chloride in a pyridine solvent. In one aspect, the mesylate of the methyl ester of ricinoleic acid is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the tosylate or mesylate is reacted with diazabicyclo-undecene in a polar, non-hydoxylic solvent of acetonitrile to form the preferred isomer of 9-cis, 11-trans octadecadienoic acid at room temperature in high yield.