CAS: 1078-28-0; 6-Methoxy-2-Methylquinoline

该化合物是一种含有分子式C11H11NO的混合循环有机化合物,其特点是在五氯丁二烯剑桥的6个位置上替换一个甲氧基组,加强了其作为有机合成中多种媒介的效用,该化合物因其反应性和结构特性而在制药,农用化学品和染料方面所发挥的作用而特别受到重视,其甲氧基组有助于改进溶性和电子效应,促进进一步功能化. 6-甲基丙烯通常用于合成复合分子,包括碱类和其他含氮的乙型循环,使其成为研究和工业应用中有价值的再剂.

结构式图片

相似化合物

6628-28-0 19490-87-0 613-21-8

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号104-94-9 对甲氧基苯胺 | CAS号75-07-0 乙醛 | CAS号123-73-9 2-丁烯醛 | CAS号64-17-5 乙醇 | CAS号856095-00-6 4-溴-6-甲氧基-2-甲基喹啉 | CAS号67-56-1 甲醇 | CAS号92-46-6 6-氯-2-甲基喹啉 | CAS号52271-43-9 N-[4-(4-methoxy... | CAS号91-63-4 2-甲基喹啉 | CAS号75433-99-7 6-甲氧基喹啉-2-羧酸 | CAS号58246-80-3 1-乙酰基-5-甲氧基吲哚 | CAS号613-21-8 6-羟基-2-甲基喹啉 | CAS号89060-22-0 6-甲氧基喹啉-4-羧醛 | CAS号42835-96-1 6-Methoxy-2-met... | CAS号475682-39-4 5-Bromo-6-metho...

合成工艺路线路线简述

    📜对甲氧苯乙烯基甲基酮置于palladium On Activated Charcoal 吡啶,盐酸羟胺,氢气,四氯苯醌,溶剂黄146,三氟乙酸酐体系中,用 乙醇,二氯甲烷 用作溶剂,化学反应 21.0H,反应生成6-甲氧基-2-甲基喹啉
    参考文献:Synthesis Of Quinolines And 2H-Dihydropyrroles By Nucleophilic Substitution At The Nitrogen Atom Of Oxime Derivatives
    标题:Synthesis Of Quinolines And 2H-Dihydropyrroles By Nucleophilic Substitution At The Nitrogen Atom Of Oxime Derivatives
    摘要:详细研究了肟衍生物的异构化,以探索o-取代肟的顺反异构化方法.基于这些发现,开发了从肟的立体异构体中简单制备氮杂环的方法.通过用三氟乙酸酐和四氯苯醌处理β-芳基酮肟,合成了喹啉.γ,δ-不饱和o-甲氧基乙酰肟在甲氧基乙酸的作用下转化为2H-二氢吡咯.
    Doi:10.1055/s-2003-42439

    专利信息


    专利号:US-7439364-B2
    优先权日:2001-05-17
    标 题 :Process for the synthesis of derivatives of halo-[2,3-F] quinoline
    发明人：CHAN ANITA W; CURRAN TIMOTHY T; IERA SILVIO; CHEW WARREN; SELLSTEDT JOHN H; VID GALINA; FEIGELSON GREG; DING ZHIXIAN
    权利人:WYETH CORP
    摘要:Methods of preparing compounds of Formula I n nare provided.

    专利号:US-2002187983-A1
    优先权日:2001-05-17
    标 题:Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline

    专利号:US-2004186123-A1
    优先权日:2001-05-17
    标题 :Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline

    专利号:US-2007123705-A1
    优先权日:2001-05-17
    标题:Process for the Synthesis of Derivatives of 2,3-Dihydro-1,4-Dioxino-[2,3-f] Quinolines

    专利号:CA-2447150-A1
    优先权日:2001-05-17
    标题 :Processes for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline

    专利号:EP-1387845-A2
    优先权日:2001-05-17
    标 题 :PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-(2,3-f) QUINOLINE

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Catalyst-Free Synthesis Of 3-(2-Quinolinemethylene)-Substituted Isoindolinones In Water
    作者:Feng Xu,Youping Tian,Jialin Sun,Kaihua Zhang,Gaoqiang Li |发布日期:2018.6
    摘要:Intramolecular Cyclization In A One-Pot Fashion, Affording The Desired 3-(2-Quinolinemethylene)-Substituted Isoindolinones In High To Excellent Yields. A Facile And Environmentally Benign Approach Toward The Synthesis Of Novel 3-Alkyl-Substituted Isoindolinones By Three-Component Reactions Of 2-Formylbenzoic Acids, Primary Amines And 2-MethylAzaarenes In Water Under Catalyst- And Additive-Free Conditions

    合成参考文献


    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 103.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 87.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 242.
    摘要:Dekeukeleire, S.; D'hooghe, M.; De Kimpe, N., Science of Synthesis Knowledge Updates, (2011) 3, 109.
    摘要:Xu, L.; Wu, X.; Xiao, J., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 274.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知