CAS: 77301-42-9; 1-(6-Methoxynaphthalen-2-yl)Ethanol

上下游产品

naproxen trichlorofluoromethane (2S)-2-(6-methoxy(2-naphthyl))propanoic acid Naprelan6-methoxy-2-acetylnaphthalene (S)-1-[2-(6-methoxynaphthyl)]ethanol (2S)-2-(6-methoxy(2-naphthyl))propanoic acid (R)-2-(6-methoxy-2-naphthyl)propionic acid

📜萘普生置于dipotassium Hydrogenphosphate,氧气,10-甲基-9-均三甲苯基吖啶高氯酸盐,Sodium Tetrahydroborate体系中,用 氯仿,甲醇 作为反应溶剂,化学反应 36.5H,以74%的收率获得产物1-(6-甲氧基-2-萘甲基)乙醇
参考文献:可见光和分子氧驱动下的羧酸的光催化脱羧羟基化反应
标题:可见光和分子氧驱动下的羧酸的光催化脱羧羟基化反应
摘要:该论文公开了羧酸的光催化直接脱羧羟基化的第一个实例.它能够以中等到高收率将各种容易获得的羧酸转化为醇.这种前所未有的方案是在极其温和的反应条件下完成的,使用分子氧(o 2)作为绿色氧化剂,并使用可见光作为驱动力.
DOI:10.1021/acs.Joc.6B01360

专利信息

专利号:US-11639326-B2
优先权日:2017-04-06
标 题 :Continuous flow synthesis of ibuprofen
发明人：COLLINS NATHAN; MALERICH JEREMIAH; SZETO JUDY; KOZOCAS JOSEPH A
权利人:STANFORD RES INST INT
摘要:This disclosure generally relates to methods of making ibuprofen, naproxen, and derivatives thereof. This disclosure also generally relates to compounds made by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:EP-2878592-B1
优先权日:2013-11-27
标题 :Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs as potential pro-drugs
发明人：KÃœCÃœKGÃœZEL ILKAY; KULABAS NECLA; SET IREM
权利人:KUECUEKGUEZEL ILKAY

专利号:US-2021114962-A1
优先权日:2017-04-06
标题 :Continuous flow synthesis of ibuprofen

专利号:EP-2878592-A1
优先权日:2013-11-27
标题 :Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs as potential pro-drugs

专利号:WO-2018187717-A1
优先权日:2017-04-06
标 题:Continuous flow synthesis of ibuprofen

专利号:CN-110903189-B
优先权日:2019-12-10
标 题:Synthesis method of chiral 2-aryl propionate