📜Dl-1,2-己二醇置于sodium Hypochlorite,Ormosil-Entrapped Tempo,碳酸氢钠体系中,用 乙腈 作为反应溶剂,以79%的收率获得产物dl-Alpha-羟基己酸 参考文献:Enhancing Selectivity In Oxidation Catalysis With Sol-gel Nanocomposites 标题:Enhancing Selectivity In Oxidation Catalysis With Sol-gel Nanocomposites 摘要:使用掺入有机催化剂 Tempo 的溶胶疏水纳米结构二氧化硅基质,可以轻松合成δ-羟基酸等有价值的有机化合物,并提高了相关的选择性:这是一种基于材料科学的合成路线,无法通过经典的均相合成实现. DOI:10.1039/b505949F
专利号:US-5817751-A 优先权日:1994-06-23 标 题 :Method for synthesis of diketopiperazine and diketomorpholine derivatives 发明人:SZARDENINGS ANNA KATRIN; CAMPBELL DAVID 权利人:AFFYMAX TECH NV 摘要:The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such methods to create libraries of diverse diketopiperazine derivatives. The present invention has application in the areas of chemical synthesis, the screening for new diketopiperazine derivatives having beneficial medical properties and the use of such screening to provide compositions and methods including diketopiperazine derivatives for treating disease.
专利号:US-6384228-B2 优先权日:1998-05-26 标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof 发明人:NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO 权利人:NIHON MEDIPHYSICS CO LTD 摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.
专利号:US-2024082118-A1 优先权日:2021-05-19 标 题:Topical compositions and methods of preparing the same 发明人:ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION 权利人:LANDA LABS 2012 LTD 摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.
专利号:US-2024254395-A1 优先权日:2021-06-02 标题 :Pyrolysis of polyurethane compound-containing material in order to recover raw materials 发明人:EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; HAHN CHRISTIAN; LODDENKEMPER TIM; JENDRZOK CAROLA 权利人:COVESTRO DEUTSCHLAND AG 摘要:The invention relates to a process according to claim 1 and pyrolysis devices used therein for the pyrolysis of pyrolysis stock comprising polyurethane-containing material, allowing carrying out pyrolysis on an industrial scale. According to the invention, even with higher amounts of pyrolysis stock an amount of pyrolysis product is obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.
专利号:US-2024352216-A1 优先权日:2021-08-20 标 题:Pyrolysis of a polymeric polyurethane compound in order to recover raw materials 发明人:EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; ALBACH ROLF 权利人:COVESTRO DEUTSCHLAND AG 摘要:The invention relates to a method according to claim 1 for the commercial implementation of a pyrolysis, and to pyrolysis devices for the pyrolysis of pyrolysis stock used in this method. The pyrolysis stock contains a polymeric compound having at least one structural polyurethane unit of the formula (I), wherein Q is a hydrocarbon group with 2 to 8 carbon atoms, preferably 3 to 8 carbon atoms, and n represents a number from 2 to 4, most preferably 2, and -* represents a covalent bond to the polymer backbone. The method and the pyrolysis device according to the invention allow, even with higher compounds of pyrolysis stock an amount of pyrolysis product to be obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.
专利号:US-2024308950-A1 优先权日:2022-08-05 标题 :Biorenewable synthesis of hydroxy-hexanoate esters 发明人:HUBER GEORGE; DELL ANNA MARCO NAZARENO 权利人:WISCONSIN ALUMNI RES FOUND 摘要:A method to make mono- or di-hydroxy-hexanoates. Triacetic acid lactone is converted to a δ-hexalactone or a 4-hydroxy-δ-hexalactone intermediate. The intermediate is treated with an acid in the presence of an alcohol to yield a 5-hydroxy-hexanoate or 4,5-dihydroxy-hexanoate.
[参考文献]: Grazyna Adamus, Et Al. Molecular Architecture Of Poly[参考文献]: Jadwiga Lyczko, Et Al. Commercial Formaldehyde Standard For Mass Calibration In Mass Spectrometry. J Mass Spectrom. 2015 Mar;50(3):463-9. [参考文献]: K J Ng, Et Al. Capillary Gas Chromatographic-Mass Spectrometric Profiles Of Trimethylsilyl Derivatives Of Organic Acids From Amniotic Fluids Of Different Gestational Age. J Chromatogr. 1982 Mar 12:228:43-50. [参考文献]: L I Woolf, Et Al. Estimation Of Branched-Chain Alpha-Keto Acids In Blood By Gas Chromatography. J Chromatogr. 1982 Sep 10;231(2):237-45.
合成参考文献
参考文献:10.1007/s00253-014-5805-5 摘要:Guo J, Peng Y, Yang X, Wang Z, Zhu A. Changes in the microbial community structure of filaments and floc formers in response to various carbon sources and feeding patterns. Applied Microbiology and Biotechnology. 2014 May 21;98(17):7633–44. doi: 10.1007/s00253-014-5805-5.