CAS: 6064-63-7; 2-Hydroxyhexanoic Acid

该化合物是一种六碳氢氧化酸,分子式为C6H12O3.它与碳化物组相比,具有α位置的氢氧基组,使其成为甲型氢氧基酸(AHA),由于有机合成,制药和特殊化学应用,由于它具有双功能反应性,该化合物被用于有机合成,制药和专用化学应用,其结构允许其酯化,聚合和切热特性,使其在可生物降解的聚合物和化妆品配方中具有价值.氢氧基和碳化物组的存在,增强了其在极地溶剂中的溶性,便于其在水溶性系统中的使用.2-Hydroxyhexanoic酸还因其在生殖合成和精密化学生产中作为中间体的潜力进行了研究.

结构式图片

相似化合物

6920-22-5 2492-75-3 636-69-1

上下游产品

2-acetoxy-hexanoic acid methyl ester thien-2-yl-DL-glycolic acid 2-amino-hexanoic acid 2-oxohexanoic acid2-hydroxyhexanoic acid ethyl ester pentanal Hexane-1,2-diol valeric acid

合成工艺路线路线简述

    📜Dl-1,2-己二醇置于sodium Hypochlorite,Ormosil-Entrapped Tempo,碳酸氢钠体系中,用 乙腈 作为反应溶剂,以79%的收率获得产物dl-Alpha-羟基己酸
    参考文献:Enhancing Selectivity In Oxidation Catalysis With Sol-gel Nanocomposites
    标题:Enhancing Selectivity In Oxidation Catalysis With Sol-gel Nanocomposites
    摘要:使用掺入有机催化剂 Tempo 的溶胶疏水纳米结构二氧化硅基质,可以轻松合成δ-羟基酸等有价值的有机化合物,并提高了相关的选择性:这是一种基于材料科学的合成路线,无法通过经典的均相合成实现.
    DOI:10.1039/b505949F

    海关参考信息

    专利信息


    专利号:US-5817751-A
    优先权日:1994-06-23
    标 题 :Method for synthesis of diketopiperazine and diketomorpholine derivatives
    发明人:SZARDENINGS ANNA KATRIN; CAMPBELL DAVID
    权利人:AFFYMAX TECH NV
    摘要:The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such methods to create libraries of diverse diketopiperazine derivatives. The present invention has application in the areas of chemical synthesis, the screening for new diketopiperazine derivatives having beneficial medical properties and the use of such screening to provide compositions and methods including diketopiperazine derivatives for treating disease.

    专利号:US-6384228-B2
    优先权日:1998-05-26
    标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof
    发明人:NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO
    权利人:NIHON MEDIPHYSICS CO LTD
    摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.

    专利号:US-2024082118-A1
    优先权日:2021-05-19
    标 题:Topical compositions and methods of preparing the same
    发明人:ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
    权利人:LANDA LABS 2012 LTD
    摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.

    专利号:US-2024254395-A1
    优先权日:2021-06-02
    标题 :Pyrolysis of polyurethane compound-containing material in order to recover raw materials
    发明人:EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; HAHN CHRISTIAN; LODDENKEMPER TIM; JENDRZOK CAROLA
    权利人:COVESTRO DEUTSCHLAND AG
    摘要:The invention relates to a process according to claim 1 and pyrolysis devices used therein for the pyrolysis of pyrolysis stock comprising polyurethane-containing material, allowing carrying out pyrolysis on an industrial scale. According to the invention, even with higher amounts of pyrolysis stock an amount of pyrolysis product is obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.

    专利号:US-2024352216-A1
    优先权日:2021-08-20
    标 题:Pyrolysis of a polymeric polyurethane compound in order to recover raw materials
    发明人:EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; ALBACH ROLF
    权利人:COVESTRO DEUTSCHLAND AG
    摘要:The invention relates to a method according to claim 1 for the commercial implementation of a pyrolysis, and to pyrolysis devices for the pyrolysis of pyrolysis stock used in this method. The pyrolysis stock contains a polymeric compound having at least one structural polyurethane unit of the formula (I), wherein Q is a hydrocarbon group with 2 to 8 carbon atoms, preferably 3 to 8 carbon atoms, and n represents a number from 2 to 4, most preferably 2, and -* represents a covalent bond to the polymer backbone. The method and the pyrolysis device according to the invention allow, even with higher compounds of pyrolysis stock an amount of pyrolysis product to be obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.

    专利号:US-2024308950-A1
    优先权日:2022-08-05
    标题 :Biorenewable synthesis of hydroxy-hexanoate esters
    发明人:HUBER GEORGE; DELL ANNA MARCO NAZARENO
    权利人:WISCONSIN ALUMNI RES FOUND
    摘要:A method to make mono- or di-hydroxy-hexanoates. Triacetic acid lactone is converted to a δ-hexalactone or a 4-hydroxy-δ-hexalactone intermediate. The intermediate is treated with an acid in the presence of an alcohol to yield a 5-hydroxy-hexanoate or 4,5-dihydroxy-hexanoate.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Grazyna Adamus, Et Al. Molecular Architecture Of Poly[参考文献]: Jadwiga Lyczko, Et Al. Commercial Formaldehyde Standard For Mass Calibration In Mass Spectrometry. J Mass Spectrom. 2015 Mar;50(3):463-9.
    [参考文献]: K J Ng, Et Al. Capillary Gas Chromatographic-Mass Spectrometric Profiles Of Trimethylsilyl Derivatives Of Organic Acids From Amniotic Fluids Of Different Gestational Age. J Chromatogr. 1982 Mar 12:228:43-50.
    [参考文献]: L I Woolf, Et Al. Estimation Of Branched-Chain Alpha-Keto Acids In Blood By Gas Chromatography. J Chromatogr. 1982 Sep 10;231(2):237-45.

    合成参考文献


    参考文献:10.1007/s00253-014-5805-5
    摘要:Guo J, Peng Y, Yang X, Wang Z, Zhu A. Changes in the microbial community structure of filaments and floc formers in response to various carbon sources and feeding patterns. Applied Microbiology and Biotechnology. 2014 May 21;98(17):7633–44. doi: 10.1007/s00253-014-5805-5.
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