CAS: 55674-63-0; (R)-2-((Tert-Butoxycarbonyl)Amino)Hexanoic Acid

相似化合物

6404-28-0 133388-96-2 125342-48-5

上下游产品

tert-butyl (R)-(1-hydroxyhexan-2-yl)carbamate tert-butyl dicarbonatedi-tert-butyl dicarbonate (4R, 5S)-4-butyl-5-(1,2-bis(isopropoxycarbonyl)hydrazino)-2-oxazolidinone N-tert-butyloxycarbonyl-L-serine methyl esterD-N-B°C-nor-leucine methyl ester tert-butyl (R)-(1-hydroxyhexan-2-yl)carbamate

📜Boc-L-丝氨酸甲酯置于sodium Tetrahydroborate,Disodium Hydrogenphosphate,重铬酸吡啶,正丁基锂,Sodium Amalgam,4-甲基苯磺酸吡啶,间氯过氧苯甲酸体系中,用 吡啶,甲醇,乙醇,二氯甲烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 89.0H,反应生成 叔丁氧羰酰基d-正亮氨酸
参考文献:从l-丝氨酸合成l和d构型的光学纯非蛋白质α-氨基酸的新方法
标题:从l-丝氨酸合成l和d构型的光学纯非蛋白质α-氨基酸的新方法
摘要:描述了由l-丝氨酸有效合成(2R)-2-Boc-氨基-3-苯基磺酰基-1-丙醇3及其对映异构体9.通过制备n-Boc-L-和d-高苯丙氨酸,-正缬氨酸和-,可以举例说明这些化合物在合成l和d构型的光学纯非蛋白质α-氨基酸的新颖通用方法中的潜力.正亮氨酸.
DOI:10.1016/s0040-4039(00)96866-7

专利信息

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-6664282-B2
优先权日:1999-09-17
标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
发明人：ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
权利人:TORREY PINES INST
摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

专利号:WO-9834113-A1
优先权日:1997-02-04
标题 :Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
发明人：OSTRESH JOHN M; MEYER JEAN-PHILIPPE; DOOLEY COLETTE T; HOUGHTEN RICHARD A; BLONDELLE SYLVIE E; SCHONER CHRISTA C
权利人:TREGA BIOSCIENCES INC
摘要:The invention provides a rapid approach for combinatorial synthesis and screening of combinatorial libraries of bicyclic guanidine compounds. The present invention further provides the compounds made by the combinatorial synthesis and individually as well as methods of using the same.

专利号:US-6359144-B1
优先权日:1997-02-04
标 题 :Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
发明人：OSTRESH JOHN M; MEYER JEAN-PHILIPPE; DOOLEY COLETTE T; BLONDELLE SYLVIE E; SCHONER CHRISTA C; HOUGHTEN RICHARD A
权利人:LION BIOSCIENCE AG
摘要:The invention provides a rapid approach for combinatorial synthesis and screening of combinatorial libraries of bicyclic guanidine compounds. The present invention further provides the compounds made by the combinatorial synthesis and individually as well as methods of using the same.

专利号:WO-9811438-A1
优先权日:1996-09-13
标题 :Synthesis of quinazolinone libraries and derivatives thereof

专利号:EP-1218337-A1
优先权日:1999-09-17
标题 :Synthesis of 3,5,7]-1h-imidazo 1,5-a]imidazol-2(3h)-one compounds