CAS: 23567-23-9; (2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-Dihydroxyphenyl)-[4,8'-Bichromane]-3,3',5,5',7,7'-Hexaol
该化合物是一种类氟化物,具体而言,一种蛋白基丁,是一种在各种植物中发现的多酚化合物,其特征特征是其食用结构,通常由两种特殊类型的粘合物组成.Procyanidin B3以其抗氧化特性而著称,这种特性有助于其潜在的健康惠益,包括心血管保护和防炎效应.它通常见于可可,苹果和浆果等食品中,并经常研究其在促进人类健康方面的作用.该化合物具有一种反映其复杂结构的分子配方,它溶于有机溶剂,但在水中则较少.Procyanidin B3还因其与各种生物系统互动的能力而得到承认,它影响细胞信号路径,并有可能提供保护性影响氧化性压力.它出现在饮食中,它与各种健康惠益有关,因此成为营养和药物研究的一个主题.
- 英文名称(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-Dihydroxyphenyl)-[4,8'-Bichromane]-3,3',5,5',7,7'-Hexaol
- 中文名称原花清素B3
- IUPAC名称(2R,2'R,3S,3'S,4S)-2,2'-bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol
- 其它别名Procyanidol B3S ; (2R,3S,4S)-2-(3,4-Dihydroxyphenyl)-4-[(2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-Chroman-8-Yl]Chromane-3,5,7-Triol ; 2Tc1A0Keaq ; Catechin-(4.Alpha.-->8)Catechin ; (4,8'-Bi-2H-1-Benzopyran)-3,3',5,5',7,7'-Hexol, 2,2'-Bis(3,4-Dihydr
- CAS编号23567-23-9
- MFCD编号:MFCD00166354
- EINECS号:621-754-2
- FDA UNII编号:2TC1A0KEAQ
- 分子式:C30H26O12分子量:578.53
- 产品CID: 1177888
- 产品分类生物化工
物理性质
- 熔点218-219 °C
- 沸点955.3±65.0 °C at 760 mmHg
- 闪点531.6±34.3 °C
- 密度1.7±0.1 g/cm3
- pKa:9.29±0.60(预测)
- PSA:220.76
- LogP:0.3
- 折射率1.803
- 蒸汽压0.0±0.3 mmHg at 25°C
- 溶解性Soluble In Acetone And Acetonitrile
- 外观形态白色粉末
- 储存条件密封干燥,2-8°C
- 产品应用该化合物用作内容确定,识别和药理实验;它作为丙酰转移酶(HAT)的特定抑制剂,有选择地禁止P300介导和受体受体感染,对活性场地以外的第300页上的地点具有约束力;它对HDAC或丙酮甲基转移酶没有影响.
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
CAS号777063-26-0 8-bromo-3,5,7,3... | CAS号20728-73-8 5,7,3',4'-四-O-苄基儿茶素 | CAS号154-23-4 儿茶精； 儿茶素； (2R,3... | CAS号490-46-0 表儿茶素(EC) | CAS号154-23-4 儿茶精； 儿茶素； (2R,3... | CAS号13306-05-3 花青素合成工艺路线路线简述
📜花旗松素置于silver Tetrafluoroborate Sodium Tetrahydroborate,溶剂黄146体系中,用 四氢呋喃,乙醇 用作溶剂,化学反应 13.0H,反应生成原花清素b3
参考文献:Oligomeric Flavanoids. Part 27. Interflavanyl Bond Formation In Procyanidins Under Neutral Conditions
标题:Oligomeric Flavanoids. Part 27. Interflavanyl Bond Formation In Procyanidins Under Neutral Conditions
摘要:Dimethyl(Methylthio)Sulfonium Tetrafluoroborate (Dmtsf) And Silver Tetrafluoroborate (Agbf4) Activate The Ci-S Bond In The Lt-Thioethers Of Flavan-3-Ols Toward Carbon Nucleophiles To Permit Formation Of The Interflavanyl Bond In Procyanidins Under Neutral Conditions. (C) 1998 Published By Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0040-4020(98)00454-2
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Belenichev I, Ryzhenko V, Popazova O, Bukhtiyarova N, Gorchakova N, Oksenych V, Kamyshnyi O. Optimization of the Search for Neuroprotectors among Bioflavonoids. Pharmaceuticals (Basel). 2024 Jul 3;17(7):877. doi: 10.3390/ph17070877.
2: Topi D, Topi A, Guclu G, Selli S, Uzlasir T, Kelebek H. Targeted analysis for the detection of phenolics and authentication of Albanian wines using LC- DAD/ESI-MS/MS combined with chemometric tools. Heliyon. 2024 May 16;10(11):e31127. doi: 10.1016/j.heliyon.2024.e31127.
3: Liu Y, Zhang L, Wang L, Tang X, Wan S, Huang Q, Ran M, Shen H, Yang Y, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J. Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment. Pharmacol Res. 2024 Feb;200:107068. doi: 10.1016/j.phrs.2024.107068. Epub 2024 Jan 15. 16(12):1692. doi: 10.3390/ph16121692.
合成参考文献
参考文献:10.1021/jf981380z
摘要:Déprez S, Mila I, Scalbert A. Carbon-14 biolabeling of (+)-catechin and proanthocyanidin oligomers in willow tree cuttings. J Agric Food Chem. 1999 Oct;47(10):4219–30. doi: 10.1021/jf981380z.
参考文献:10.1021/jf970468u
摘要:de Freitas VA, Glories, Laguerre. Incidence of Molecular Structure in Oxidation of Grape Seed Procyanidins. J Agric Food Chem. 1998 Feb 16;46(2):376–82. doi: 10.1021/jf970468u.
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尽可能描述清楚需求与问题信息
